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Protein

Gibberellin receptor GID1B

Gene

GID1B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active gibberellin GA4, but has no affinity for the biologically inactive GAs. In response to GA, interacts with specific DELLA proteins, known as repressors of GA-induced growth, and targets them for degradation via proteasome. Seems to be required for GA signaling that controls root growth, seed germination and flower development. May function as a dominant GA receptor at low GA concentrations in germination. Partially redundant with GID1A and GID1C.3 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei127GibberellinBy similarity1
Active sitei191PROSITE-ProRule annotationBy similarity1
Binding sitei191GibberellinBy similarity1
Active sitei289PROSITE-ProRule annotationBy similarity1
Binding sitei320Gibberellin; via amide nitrogenBy similarity1

GO - Molecular functioni

GO - Biological processi

  • catabolic process Source: GO_Central
  • floral organ morphogenesis Source: TAIR
  • fruit morphogenesis Source: CAFA
  • gibberellin mediated signaling pathway Source: TAIR
  • negative regulation of gene expression Source: CAFA
  • positive regulation of fertilization Source: CAFA
  • positive regulation of gibberellic acid mediated signaling pathway Source: TAIR
  • response to gibberellin Source: TAIR

Keywordsi

Molecular functionHydrolase, Receptor
Biological processGibberellin signaling pathway

Enzyme and pathway databases

BioCyciARA:AT3G63010-MONOMER

Protein family/group databases

ESTHERiarath-GID1B Plant_carboxylesterase

Names & Taxonomyi

Protein namesi
Recommended name:
Gibberellin receptor GID1B (EC:3.-.-.-)
Alternative name(s):
AtCXE14
Carboxylesterase 14
GID1-like protein 2
Protein GA INSENSITIVE DWARF 1B
Short name:
AtGID1B
Gene namesi
Name:GID1B
Synonyms:CXE14, GID1L2
Ordered Locus Names:At3g63010
ORF Names:T20O10.110
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G63010
TAIRilocus:2099152 AT3G63010

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

No visible phenotype under normal growth condition.2 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000715592 – 358Gibberellin receptor GID1BAdd BLAST357

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ9LYC1

Expressioni

Tissue specificityi

Widely expressed.1 Publication

Gene expression databases

ExpressionAtlasiQ9LYC1 baseline and differential
GenevisibleiQ9LYC1 AT

Interactioni

Subunit structurei

Interacts with the DELLA proteins GAI, RGA, RGL1, RGL2 and RGL3 in a GA-dependent manner.3 Publications

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi10790, 4 interactors
DIPiDIP-37662N
IntActiQ9LYC1, 6 interactors
STRINGi3702.AT3G63010.1

Structurei

3D structure databases

ProteinModelPortaliQ9LYC1
SMRiQ9LYC1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni115 – 116Gibberellin bindingBy similarity2

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi113 – 115Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion holeBy similarity3

Sequence similaritiesi

Belongs to the 'GDXG' lipolytic enzyme family.Curated

Phylogenomic databases

eggNOGiKOG1515 Eukaryota
COG0657 LUCA
HOGENOMiHOG000152323
InParanoidiQ9LYC1
KOiK14493
OMAiTMAGGNE
OrthoDBiEOG09360EOQ
PhylomeDBiQ9LYC1

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR013094 AB_hydrolase_3
IPR002168 Lipase_GDXG_HIS_AS
IPR033140 Lipase_GDXG_put_SER_AS
PfamiView protein in Pfam
PF07859 Abhydrolase_3, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit
PROSITEiView protein in PROSITE
PS01173 LIPASE_GDXG_HIS, 1 hit
PS01174 LIPASE_GDXG_SER, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9LYC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGGNEVNLN ECKRIVPLNT WVLISNFKLA YKVLRRPDGS FNRDLAEFLD
60 70 80 90 100
RKVPANSFPL DGVFSFDHVD STTNLLTRIY QPASLLHQTR HGTLELTKPL
110 120 130 140 150
STTEIVPVLI FFHGGSFTHS SANSAIYDTF CRRLVTICGV VVVSVDYRRS
160 170 180 190 200
PEHRYPCAYD DGWNALNWVK SRVWLQSGKD SNVYVYLAGD SSGGNIAHNV
210 220 230 240 250
AVRATNEGVK VLGNILLHPM FGGQERTQSE KTLDGKYFVT IQDRDWYWRA
260 270 280 290 300
YLPEGEDRDH PACNPFGPRG QSLKGVNFPK SLVVVAGLDL VQDWQLAYVD
310 320 330 340 350
GLKKTGLEVN LLYLKQATIG FYFLPNNDHF HCLMEELNKF VHSIEDSQSK

SSPVLLTP
Length:358
Mass (Da):40,300
Last modified:October 1, 2000 - v1
Checksum:i8D24F47BC40CE4D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL163816 Genomic DNA Translation: CAB87746.1
CP002686 Genomic DNA Translation: AEE80423.1
AK228182 mRNA Translation: BAF00137.1
BT028997 mRNA Translation: ABI93906.1
PIRiT48090
RefSeqiNP_191860.1, NM_116166.5
UniGeneiAt.47986

Genome annotation databases

EnsemblPlantsiAT3G63010.1; AT3G63010.1; AT3G63010
GeneIDi825476
GrameneiAT3G63010.1; AT3G63010.1; AT3G63010
KEGGiath:AT3G63010

Similar proteinsi

Entry informationi

Entry nameiGID1B_ARATH
AccessioniPrimary (citable) accession number: Q9LYC1
Secondary accession number(s): Q0WRW2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health