Q9LYB4 (GPX5_ARATH) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 77.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable glutathione peroxidase 5 EC=1.11.1.9 | ||||||
| Gene names |
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| Organism | Arabidopsis thaliana (Mouse-ear cress) | ||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Protein attributes
| Sequence length | 173 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | May constitute a glutathione peroxidase-like protective system against oxidative stresses By similarity. |
| Catalytic activity | 2 glutathione + H2O2 = glutathione disulfide + 2 H2O. |
| Tissue specificity | Ubiquitous. Ref.5 |
| Induction | By salt stress, osmotic stress and metals. Down-regulated by abscisic acid (ABA). Ref.5 |
| Sequence similarities | Belongs to the glutathione peroxidase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Stress response |
| Molecular function | Oxidoreductase Peroxidase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | embryo development ending in seed dormancy Inferred from mutant phenotype. Source: TAIR response to oxidative stressInferred from electronic annotation. Source: InterPro |
| Cellular component | plasma membrane Inferred from direct assay. Source: TAIR |
| Molecular function | glutathione peroxidase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana." Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. Tabata S.Nature 408:820-822(2000) [PubMed: 11130713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [2] | The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia. |
| [3] | "Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. Ecker J.R.Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia. |
| [4] | "Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
| [5] | "Glutathione peroxidase genes in Arabidopsis are ubiquitous and regulated by abiotic stresses through diverse signaling pathways." Rodriguez Milla M.A., Maurer A., Rodriguez Huete A., Gustafson J.P. Plant J. 36:602-615(2003) [PubMed: 14617062] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE, TISSUE SPECIFICITY, INDUCTION. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AL163816 Genomic DNA. Translation: CAB87753.1. CP002686 Genomic DNA. Translation: AEE80432.1. BT003821 mRNA. Translation: AAO41874.1. BT005137 mRNA. Translation: AAO50670.1. AY085116 mRNA. Translation: AAM61670.1. |
| IPI | IPI00530140. |
| PIR | T48097. |
| RefSeq | NP_191867.1. NM_116173.3. |
| UniGene | At.34000. At.43439. |
3D structure databases | |
| ProteinModelPortal | Q9LYB4. |
| SMR | Q9LYB4. Positions 8-170. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | Q9LYB4. 1 interaction. |
| STRING | Q9LYB4. |
Protein family/group databases | |
| PeroxiBase | 2475. AtGPx05. |
Proteomic databases | |
| PRIDE | Q9LYB4. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblPlants | AT3G63080.1; AT3G63080.1; AT3G63080. |
| GeneID | 825483. |
| GenomeReviews | Gene locus AT3G63080 in contig BA000014_GR. |
| KEGG | ath:AT3G63080. |
| NMPDR | fig|3702.1.peg.17696. |
Organism-specific databases | |
| GeneFarm | 2054. 163. |
| TAIR | At3g63080. |
Phylogenomic databases | |
| eggNOG | KOG1651. |
| GeneTree | EPGT00050000008661. |
| HOGENOM | HBG648990. |
| InParanoid | Q9LYB4. |
| OMA | CGFTESN. |
| PhylomeDB | Q9LYB4. |
| ProtClustDB | CLSN2684302. |
Gene expression databases | |
| ArrayExpress | Q9LYB4. |
| Genevestigator | Q9LYB4. |
| GermOnline | AT3G63080. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR000889. Glutathione_peroxidase. IPR012336. Thioredoxin-like_fold. [Graphical view] |
| Gene3D | G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. |
| KO | K00432. |
| PANTHER | PTHR11592. Glut_peroxidase. 1 hit. |
| Pfam | PF00255. GSHPx. 1 hit. [Graphical view] |
| PIRSF | PIRSF000303. Glutathion_perox. 1 hit. |
| PRINTS | PR01011. GLUTPROXDASE. |
| SUPFAM | SSF52833. Thiordxn-like_fd. 1 hit. |
| PROSITE | PS00460. GLUTATHIONE_PEROXID_1. 1 hit. PS00763. GLUTATHIONE_PEROXID_2. 1 hit. PS51355. GLUTATHIONE_PEROXID_3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GPX5_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9LYB4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with