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Protein

Cell division protein FtsZ homolog 2-2, chloroplastic

Gene

FTSZ2-2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Exhibits GTPase activity (By similarity). Component of the plastid division machinery that forms a contractile ring at the division site.By similarity2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei244GTPBy similarity1
Binding sitei248GTPBy similarity1
Binding sitei292GTPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi124 – 128GTPBy similarity5
Nucleotide bindingi213 – 215GTPBy similarity3

GO - Molecular functioni

  • GTPase activity Source: UniProtKB
  • GTP binding Source: UniProtKB
  • identical protein binding Source: IntAct
  • protein self-association Source: UniProtKB

GO - Biological processi

  • chloroplast fission Source: UniProtKB
  • chloroplast organization Source: TAIR

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZ homolog 2-2, chloroplastic
Short name:
AtFtsZ2-2
Alternative name(s):
Plastid division protein FTSZ2-2
Gene namesi
Name:FTSZ2-2
Ordered Locus Names:At3g52750
ORF Names:F3C22.150
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G52750
TAIRilocus:2083258 AT3G52750

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid, Thylakoid

Pathology & Biotechi

Disruption phenotypei

Slightly reduced number of large chloroplasts due to impaired plastid division.2 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000406891? – 473Cell division protein FtsZ homolog 2-2, chloroplastic
Transit peptidei1 – ?ChloroplastSequence analysis

Proteomic databases

PaxDbiQ9LXJ0
PRIDEiQ9LXJ0

Expressioni

Gene expression databases

ExpressionAtlasiQ9LXJ0 baseline and differential
GenevisibleiQ9LXJ0 AT

Interactioni

Subunit structurei

Aggregates to form a contractile ring-like structure. Self-interacts and binds to FTSZ1 in heteropolymers to form two morphologically distinct types of filaments, termed type-I (smooth filaments) and -II (rough filaments), in a GTP-dependent manner. Part of a complex made of ARC3, ARC6, FTSZ1 and FTSZ2. Interacts (via C-terminus) with ARC6.2 Publications

Binary interactionsi

Show more details

GO - Molecular functioni

  • identical protein binding Source: IntAct
  • protein self-association Source: UniProtKB

Protein-protein interaction databases

BioGridi9758, 5 interactors
IntActiQ9LXJ0, 4 interactors
STRINGi3702.AT3G52750.1

Structurei

3D structure databases

ProteinModelPortaliQ9LXJ0
SMRiQ9LXJ0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FtsZ family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410IEJ4 Eukaryota
COG0206 LUCA
HOGENOMiHOG000049094
InParanoidiQ9LXJ0
KOiK03531
OMAiGDNSRSH
OrthoDBiEOG093604MZ
PhylomeDBiQ9LXJ0

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9LXJ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAYVSPCLT PPDSRVLTVL RKSVLPDHHL GTRVGCLRMS EGTTKRYRVV
60 70 80 90 100
ASHKYESSSI RNSLNSHSTS HFQSQDSFLN LHPEISMLNP RKETSSVPIT
110 120 130 140 150
EDLDELSTPN TYNEARIKVI GVGGGGSNAV NRMIESEMIG VEFWIVNTDI
160 170 180 190 200
QAMRISPVFP DNRLQIGKEL TRGLGAGGNP EIGMNAATES KEAIQEALYG
210 220 230 240 250
SDMVFVTAGM GGGTGTGGAP IIAGVAKAMG ILTVGIVTTP FSFEGRRRAL
260 270 280 290 300
QAQEGIAALR DNVDTLIVIP NDKLLAAVSQ STPVTEAFNL ADDILRQGVR
310 320 330 340 350
GISDIITIPG LVNVDFADVR AIMANAGSSL MGIGTATGKT RARDAALNAI
360 370 380 390 400
QSPLLDIGIE RATGIVWNIT GGSDLTLFEV NAAAEVIYDL VDPTANLIFG
410 420 430 440 450
AVVDPSYSGQ ISITLIATGF KRQEEGEGRP LQATQADASM GATRRPSSSF
460 470
TEGSSIEIPE FLKKKGRSRY PRL
Length:473
Mass (Da):50,317
Last modified:October 1, 2000 - v1
Checksum:i96A32AC96CFCEDB3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti269I → N in AAL07180 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF384167 mRNA Translation: AAK63846.1
AL353912 Genomic DNA Translation: CAB89236.1
CP002686 Genomic DNA Translation: AEE78989.1
CP002686 Genomic DNA Translation: ANM65557.1
CP002686 Genomic DNA Translation: ANM65558.1
AY056331 mRNA Translation: AAL07180.1
AY150504 mRNA Translation: AAN13020.1
PIRiT49028
RefSeqiNP_001327516.1, NM_001339587.1
NP_001327517.1, NM_001339586.1
NP_190843.1, NM_115135.3
UniGeneiAt.1742

Genome annotation databases

EnsemblPlantsiAT3G52750.1; AT3G52750.1; AT3G52750
AT3G52750.2; AT3G52750.2; AT3G52750
AT3G52750.3; AT3G52750.3; AT3G52750
GeneIDi824441
GrameneiAT3G52750.1; AT3G52750.1; AT3G52750
AT3G52750.2; AT3G52750.2; AT3G52750
AT3G52750.3; AT3G52750.3; AT3G52750
KEGGiath:AT3G52750

Similar proteinsi

Entry informationi

Entry nameiFTZ22_ARATH
AccessioniPrimary (citable) accession number: Q9LXJ0
Secondary accession number(s): Q93ZQ7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health