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Protein

Purple acid phosphatase 21

Gene

PAP21

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactori

Protein has several cofactor binding sites:
  • Fe cationBy similarityNote: Binds 1 Fe cation per subunit.By similarity
  • Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi152IronBy similarity1
Metal bindingi179IronBy similarity1
Metal bindingi179ZincBy similarity1
Metal bindingi182IronBy similarity1
Metal bindingi212ZincBy similarity1
Binding sitei212SubstrateBy similarity1
Metal bindingi296ZincBy similarity1
Active sitei306Proton donorBy similarity1
Metal bindingi333ZincBy similarity1
Metal bindingi335IronBy similarity1

GO - Molecular functioni

  • acid phosphatase activity Source: TAIR
  • metal ion binding Source: UniProtKB-KW

Keywordsi

Molecular functionHydrolase
LigandIron, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciARA:AT3G52810-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Purple acid phosphatase 21 (EC:3.1.3.2)
Gene namesi
Name:PAP21
Synonyms:AT5
Ordered Locus Names:At3g52810
ORF Names:F3C22.210
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G52810.
TAIRilocus:2083218. AT3G52810.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000037282426 – 437Purple acid phosphatase 21Add BLAST412

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi30N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9LXI4.

Expressioni

Tissue specificityi

Expressed flowers and siliques.1 Publication

Gene expression databases

GenevisibleiQ9LXI4. AT.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi3702.AT3G52810.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LXI4.
SMRiQ9LXI4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni333 – 335Substrate bindingBy similarity3

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1378. Eukaryota.
COG1409. LUCA.
HOGENOMiHOG000238330.
InParanoidiQ9LXI4.
OMAiFIVSHGR.
OrthoDBiEOG09360ARG.
PhylomeDBiQ9LXI4.

Family and domain databases

Gene3Di2.60.40.380. 1 hit.
3.60.21.10. 1 hit.
InterProiView protein in InterPro
IPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
IPR008963. Purple_acid_Pase-like_N.
IPR015914. Purple_acid_Pase_N.
IPR025733. Purple_acid_PPase_C_dom.
PfamiView protein in Pfam
PF00149. Metallophos. 1 hit.
PF14008. Metallophos_C. 1 hit.
PF16656. Pur_ac_phosph_N. 1 hit.
SUPFAMiSSF49363. SSF49363. 1 hit.
SSF56300. SSF56300. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9LXI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKMKIFGFL ISFSLFFLSP FVCQANYDSN FTRPPPRPLF IVSHGRPKFY
60 70 80 90 100
PQQVHISLAG KDHMRVTYTT DDLNVASMVE YGKHPKKYDK KTAGESTSYT
110 120 130 140 150
YFFYNSGKIH HVKIGPLKPN TKYYYRCGGH GDEFSFKTPP SKFPIEFAVA
160 170 180 190 200
GDLGQTDWTV RTLDQIRKRD FDVFLLPGDL SYADTHQPLW DSFGRLLETL
210 220 230 240 250
ASTRPWMVTE GNHEIESFPT NDHISFKSYN ARWLMPHAES LSHSNLYYSF
260 270 280 290 300
DVAGVHTVML GSYTPYESHS DQYHWLQADL RKVDRKKTPW LVVVMHTPWY
310 320 330 340 350
STNKAHYGEG EKMRSALESL LYRAQVDVVF AGHVHTYERF KPIYNKKADP
360 370 380 390 400
CGPMYITIGD GGNREGLALR FKKPQSPLSE FRESSFGHGR LRIIDHKRAH
410 420 430
WSWHRNNDEM SSIADEVSFE SPRTSSHCHS NRYRGEI
Length:437
Mass (Da):50,641
Last modified:October 1, 2000 - v1
Checksum:iB3416E8248BC5AB1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF492667 mRNA. Translation: AAM15916.1.
AL353912 Genomic DNA. Translation: CAB89242.1.
CP002686 Genomic DNA. Translation: AEE78996.1.
PIRiT49034.
RefSeqiNP_190849.1. NM_115141.3.
UniGeneiAt.35260.

Genome annotation databases

EnsemblPlantsiAT3G52810.1; AT3G52810.1; AT3G52810.
GeneIDi824447.
GrameneiAT3G52810.1; AT3G52810.1; AT3G52810.
KEGGiath:AT3G52810.

Similar proteinsi

Entry informationi

Entry nameiPPA21_ARATH
AccessioniPrimary (citable) accession number: Q9LXI4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: October 1, 2000
Last modified: October 25, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families