Reviewed,
UniProtKB/Swiss-Prot Q9LX83 (PPA19_ARATH)
Last modified
October 13, 2009.
Version 43.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Purple acid phosphatase 19 EC=3.1.3.2 | ||||||
| Gene names |
| ||||||
| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 388 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | A phosphate monoester + H2O = an alcohol + phosphate. |
| Cofactor | Binds 1 iron ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity. |
| Subunit structure | Homodimer By similarity. |
| Subcellular location | Secreted By similarity. |
| Tissue specificity | Specifically expressed in flowers. Ref.3 |
| Sequence similarities | Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Secreted |
| Domain | Signal |
| Ligand | Iron Metal-binding Zinc |
| Molecular function | Hydrolase |
| PTM | Glycoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Cellular component | extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | acid phosphatase activity Inferred from electronic annotation. Source: EC iron ion bindingInferred from electronic annotation. Source: UniProtKB-KW zinc ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 24 | 24 | Potential | ||||||
| Chain | 25 – 388 | 364 | Purple acid phosphatase 19 | PRO_0000372822 | |||||
Regions | |||||||||
| Region | 275 – 277 | 3 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Active site | 248 | 1 | Proton donor By similarity | ||||||
| Metal binding | 145 | 1 | Iron By similarity | ||||||
| Metal binding | 145 | 1 | Zinc By similarity | ||||||
| Metal binding | 148 | 1 | Iron By similarity | ||||||
| Metal binding | 182 | 1 | Zinc By similarity | ||||||
| Metal binding | 238 | 1 | Zinc By similarity | ||||||
| Metal binding | 275 | 1 | Zinc By similarity | ||||||
| Metal binding | 277 | 1 | Iron By similarity | ||||||
| Binding site | 182 | 1 | Substrate By similarity | ||||||
Amino acid modifications | |||||||||
| Glycosylation | 97 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 111 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 226 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 291 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 348 | 1 | N-linked (GlcNAc...) Potential | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana." Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.  Tabata S.Nature 408:820-822(2000) [PubMed: 11130713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [2] | "Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation." Li D., Zhu H., Liu K., Liu X., Leggewie G., Udvardi M., Wang D. J. Biol. Chem. 277:27772-27781(2002) [PubMed: 12021284] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE. |
| [3] | "Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower." Zhu H., Qian W., Lu X., Li D., Liu X., Liu K., Wang D. Plant Mol. Biol. 59:581-594(2005) [PubMed: 16244908] [Abstract] Cited for: TISSUE SPECIFICITY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| AL355775 Genomic DNA. Translation: CAB90939.1. | |
| IPI | IPI00545983. |
| PIR | T49253. |
| RefSeq | NP_190198.1. |
| UniGene | At.51222 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1KBP based on UniProtKB P80366. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 823755. |
| GenomeReviews | Gene locus AT3G46120 in contig BA000014_GR. |
| KEGG | ath:AT3G46120. |
| NMPDR | fig|3702.1.peg.15827. |
Organism-specific databases | |
| TAIR | At3g46120. |
Gene expression databases | |
| Genevestigator | Q9LX83. |
Family and domain databases | |
| InterPro | IPR004843. M-pesterase. [Graphical view] |
| Pfam | PF00149. Metallophos. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PPA19_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9LX83 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |
