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Protein

Purple acid phosphatase 19

Gene

PAP19

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactori

Protein has several cofactor binding sites:
  • Fe cationBy similarityNote: Binds 1 Fe cation per subunit.By similarity
  • Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi145IronBy similarity1
Metal bindingi145ZincBy similarity1
Metal bindingi148IronBy similarity1
Metal bindingi182ZincBy similarity1
Binding sitei182SubstrateBy similarity1
Metal bindingi238ZincBy similarity1
Active sitei248Proton donorBy similarity1
Metal bindingi275ZincBy similarity1
Metal bindingi277IronBy similarity1

GO - Molecular functioni

  • acid phosphatase activity Source: TAIR
  • metal ion binding Source: UniProtKB-KW

Keywordsi

Molecular functionHydrolase
LigandIron, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciARA:AT3G46120-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Purple acid phosphatase 19 (EC:3.1.3.2)
Gene namesi
Name:PAP19
Ordered Locus Names:At3g46120
ORF Names:F12M12.90
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G46120
TAIRilocus:2075341 AT3G46120

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000037282225 – 388Purple acid phosphatase 19Add BLAST364

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi97N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi111N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi226N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi291N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi348N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9LX83
PRIDEiQ9LX83

Expressioni

Tissue specificityi

Specifically expressed in flowers.1 Publication

Gene expression databases

ExpressionAtlasiQ9LX83 differential
GenevisibleiQ9LX83 AT

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi3702.AT3G46120.1

Structurei

3D structure databases

ProteinModelPortaliQ9LX83
SMRiQ9LX83
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni275 – 277Substrate bindingBy similarity3

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1378 Eukaryota
COG1409 LUCA
HOGENOMiHOG000238330
InParanoidiQ9LX83
KOiK22390
OMAiASAYIII
OrthoDBiEOG093706NJ
PhylomeDBiQ9LX83

Family and domain databases

Gene3Di3.60.21.101 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR008963 Purple_acid_Pase-like_N
IPR015914 Purple_acid_Pase_N
IPR025733 Purple_acid_PPase_C_dom
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PF14008 Metallophos_C, 1 hit
PF16656 Pur_ac_phosph_N, 1 hit
SUPFAMiSSF49363 SSF49363, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9LX83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLNHLTLVC SAIALLSIFV VSQAGVTSTH VRVSEPSEEM PLETFPPPAC
60 70 80 90 100
YNAPEQVHIT QGDHAGRGMI ISWVTPLNED GSNVVTYWIA NSDGSDNKSA
110 120 130 140 150
LATTSSYRYF NYTSGYLYHA TIKGLETLYN YMSNPKGQAV LFAGDLSYAD
160 170 180 190 200
DHPNHDQRKW DSYGRFVEPS AAYQPWIWAA GNHEIDYAES IPHKVHLHFG
210 220 230 240 250
TKSNELQLTS SYSPLTQLMD ELKKVNRSET PWLIVLVHAP WYNSNNYHYM
260 270 280 290 300
EGESMRVTFE PWFVENKVDI VFAGHVHAYE RSERISNIQY NITDGMSTPV
310 320 330 340 350
KDQNAPVYIT IGDGGNIEGI ANNFIDPQPS YSAFREASFG HAILEIKNRT
360 370 380
HAHYTWHRNK EDEFIPEAVI ADSIWLKNRY YLREEETS
Length:388
Mass (Da):44,053
Last modified:October 1, 2000 - v1
Checksum:i8F253A1F649CCDB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL355775 Genomic DNA Translation: CAB90939.1
CP002686 Genomic DNA Translation: AEE78116.1
PIRiT49253
RefSeqiNP_190198.1, NM_114481.1
UniGeneiAt.51222

Genome annotation databases

EnsemblPlantsiAT3G46120.1; AT3G46120.1; AT3G46120
GeneIDi823755
GrameneiAT3G46120.1; AT3G46120.1; AT3G46120
KEGGiath:AT3G46120

Similar proteinsi

Entry informationi

Entry nameiPPA19_ARATH
AccessioniPrimary (citable) accession number: Q9LX83
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome