Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9LX83 (PPA19_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purple acid phosphatase 19

EC=3.1.3.2
Gene names
Name:PAP19
Ordered Locus Names:At3g46120
ORF Names:F12M12.90
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length388 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactor

Binds 1 iron ion per subunit By similarity.

Binds 1 zinc ion per subunit By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Secreted By similarity.

Tissue specificity

Specifically expressed in flowers. Ref.4

Sequence similarities

Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   LigandIron
Metal-binding
Zinc
   Molecular functionHydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processdephosphorylation

Inferred from sequence or structural similarity Ref.4. Source: GOC

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacid phosphatase activity

Inferred from sequence or structural similarity Ref.4. Source: TAIR

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 388364Purple acid phosphatase 19
PRO_0000372822

Regions

Region275 – 2773Substrate binding By similarity

Sites

Active site2481Proton donor By similarity
Metal binding1451Iron By similarity
Metal binding1451Zinc By similarity
Metal binding1481Iron By similarity
Metal binding1821Zinc By similarity
Metal binding2381Zinc By similarity
Metal binding2751Zinc By similarity
Metal binding2771Iron By similarity
Binding site1821Substrate By similarity

Amino acid modifications

Glycosylation971N-linked (GlcNAc...) Potential
Glycosylation1111N-linked (GlcNAc...) Potential
Glycosylation2261N-linked (GlcNAc...) Potential
Glycosylation2911N-linked (GlcNAc...) Potential
Glycosylation3481N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9LX83 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 8F253A1F649CCDB0

FASTA38844,053
        10         20         30         40         50         60 
MGLNHLTLVC SAIALLSIFV VSQAGVTSTH VRVSEPSEEM PLETFPPPAC YNAPEQVHIT 

        70         80         90        100        110        120 
QGDHAGRGMI ISWVTPLNED GSNVVTYWIA NSDGSDNKSA LATTSSYRYF NYTSGYLYHA 

       130        140        150        160        170        180 
TIKGLETLYN YMSNPKGQAV LFAGDLSYAD DHPNHDQRKW DSYGRFVEPS AAYQPWIWAA 

       190        200        210        220        230        240 
GNHEIDYAES IPHKVHLHFG TKSNELQLTS SYSPLTQLMD ELKKVNRSET PWLIVLVHAP 

       250        260        270        280        290        300 
WYNSNNYHYM EGESMRVTFE PWFVENKVDI VFAGHVHAYE RSERISNIQY NITDGMSTPV 

       310        320        330        340        350        360 
KDQNAPVYIT IGDGGNIEGI ANNFIDPQPS YSAFREASFG HAILEIKNRT HAHYTWHRNK 

       370        380 
EDEFIPEAVI ADSIWLKNRY YLREEETS 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation."
Li D., Zhu H., Liu K., Liu X., Leggewie G., Udvardi M., Wang D.
J. Biol. Chem. 277:27772-27781(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[4]"Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower."
Zhu H., Qian W., Lu X., Li D., Liu X., Liu K., Wang D.
Plant Mol. Biol. 59:581-594(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL355775 Genomic DNA. Translation: CAB90939.1.
CP002686 Genomic DNA. Translation: AEE78116.1.
PIRT49253.
RefSeqNP_190198.1. NM_114481.1.
UniGeneAt.51222.

3D structure databases

ProteinModelPortalQ9LX83.
SMRQ9LX83. Positions 39-381.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT3G46120.1-P.

Proteomic databases

PaxDbQ9LX83.
PRIDEQ9LX83.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G46120.1; AT3G46120.1; AT3G46120.
GeneID823755.
KEGGath:AT3G46120.

Organism-specific databases

TAIRAT3G46120.

Phylogenomic databases

eggNOGNOG239147.
HOGENOMHOG000238330.
InParanoidQ9LX83.
PhylomeDBQ9LX83.

Enzyme and pathway databases

BioCycARA:AT3G46120-MONOMER.

Gene expression databases

GenevestigatorQ9LX83.

Family and domain databases

Gene3D2.60.40.380. 1 hit.
InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR008963. Purple_acid_Pase-like_N.
IPR015914. Purple_acid_Pase_N.
IPR025733. Purple_acid_PPase_C_dom.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
PF14008. Metallophos_C. 1 hit.
[Graphical view]
SUPFAMSSF49363. SSF49363. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPA19_ARATH
AccessionPrimary (citable) accession number: Q9LX83
Entry history
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names