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Q9LVQ8

- P2C80_ARATH

UniProt

Q9LVQ8 - P2C80_ARATH

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Protein

Probable protein phosphatase 2C 80

Gene

At5g66720

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi204 – 2041Manganese 1By similarity
Metal bindingi204 – 2041Manganese 2By similarity
Metal bindingi205 – 2051Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi336 – 3361Manganese 2By similarity
Metal bindingi402 – 4021Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT5G66720-MONOMER.
ARA:GQT-848-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 80 (EC:3.1.3.16)
Short name:
AtPP2C80
Gene namesi
Ordered Locus Names:At5g66720
ORF Names:MSN2.11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 5

Organism-specific databases

TAIRiAT5G66720.

Subcellular locationi

GO - Cellular componenti

  1. chloroplast Source: TAIR
  2. chloroplast stroma Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 414414Probable protein phosphatase 2C 80PRO_0000367999Add
BLAST

Proteomic databases

PaxDbiQ9LVQ8.
PRIDEiQ9LVQ8.

Expressioni

Gene expression databases

GenevestigatoriQ9LVQ8.

Interactioni

Protein-protein interaction databases

BioGridi22047. 12 interactions.
IntActiQ9LVQ8. 12 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ9LVQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini170 – 411242PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000239282.
InParanoidiQ9LVQ8.
KOiK17508.
OMAiGSFTINC.
PhylomeDBiQ9LVQ8.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9LVQ8-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSATALSRLN PVSQFGFQRI VAGKSKSFFS NSGQRRLFSD SSRFRQAMAA
60 70 80 90 100
SGSLPVFGDA CLDDLVTTCS NGLDFTKKRS SGGSFTINCP VASMRLGKRG
110 120 130 140 150
GMMKNRLVCH YSVVDPLEKS RALFGTLSKS VHTSPMACFS VGPAHELSSL
160 170 180 190 200
NGGSQESPPT TTTSLKSLRL VSGSCYLPHP EKEATGGEDA HFICDEEQAI
210 220 230 240 250
GVADGVGGWA EVGVNAGLFS RELMSYSVSA IQEQHKGSSI DPLVVLEKAH
260 270 280 290 300
SQTKAKGSST ACIIVLKDKG LHAINLGDSG FTVVREGTTV FQSPVQQHGF
310 320 330 340 350
NFTYQLESGN SADVPSSGQV FTIDVQSGDV IVAGTDGVYD NLYNEEITGV
360 370 380 390 400
VVSSVRAGLD PKGTAQKIAE LARQRAVDKK RQSPFATAAQ EAGYRYYGGK
410
LDDITAVVSY VTSS
Length:414
Mass (Da):43,873
Last modified:October 1, 2000 - v1
Checksum:i795E4D79381D5789
GO
Isoform 2 (identifier: Q9LVQ8-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     167-169: Missing.

Note: May be due to a competing acceptor splice site. No experimental confirmation available.

Show »
Length:411
Mass (Da):43,517
Checksum:iFF894EE7D74F49E3
GO

Sequence cautioni

The sequence BX833253 differs from that shown. Reason: Sequencing errors.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei167 – 1693Missing in isoform 2. 1 PublicationVSP_036777

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB018119 Genomic DNA. Translation: BAA97278.1.
CP002688 Genomic DNA. Translation: AED98255.1.
CP002688 Genomic DNA. Translation: AED98256.1.
AK117127 mRNA. Translation: BAC41805.1.
AY136405 mRNA. Translation: AAM97071.1.
BT000228 mRNA. Translation: AAN15547.1.
BX833253 mRNA. No translation available.
RefSeqiNP_201473.1. NM_126070.3. [Q9LVQ8-1]
NP_975004.1. NM_203275.1. [Q9LVQ8-2]
UniGeneiAt.28853.

Genome annotation databases

EnsemblPlantsiAT5G66720.1; AT5G66720.1; AT5G66720. [Q9LVQ8-1]
GeneIDi836805.
KEGGiath:AT5G66720.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB018119 Genomic DNA. Translation: BAA97278.1 .
CP002688 Genomic DNA. Translation: AED98255.1 .
CP002688 Genomic DNA. Translation: AED98256.1 .
AK117127 mRNA. Translation: BAC41805.1 .
AY136405 mRNA. Translation: AAM97071.1 .
BT000228 mRNA. Translation: AAN15547.1 .
BX833253 mRNA. No translation available.
RefSeqi NP_201473.1. NM_126070.3. [Q9LVQ8-1 ]
NP_975004.1. NM_203275.1. [Q9LVQ8-2 ]
UniGenei At.28853.

3D structure databases

ProteinModelPortali Q9LVQ8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 22047. 12 interactions.
IntActi Q9LVQ8. 12 interactions.

Proteomic databases

PaxDbi Q9LVQ8.
PRIDEi Q9LVQ8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT5G66720.1 ; AT5G66720.1 ; AT5G66720 . [Q9LVQ8-1 ]
GeneIDi 836805.
KEGGi ath:AT5G66720.

Organism-specific databases

TAIRi AT5G66720.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000239282.
InParanoidi Q9LVQ8.
KOi K17508.
OMAi GSFTINC.
PhylomeDBi Q9LVQ8.

Enzyme and pathway databases

BioCyci ARA:AT5G66720-MONOMER.
ARA:GQT-848-MONOMER.

Gene expression databases

Genevestigatori Q9LVQ8.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones."
    Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H., Tabata S.
    DNA Res. 7:31-63(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: cv. Columbia.
  5. "Whole genome sequence comparisons and 'full-length' cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation."
    Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M., Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M., Weissenbach J., Salanoubat M.
    Genome Res. 14:406-413(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Strain: cv. Columbia.
  6. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C80_ARATH
AccessioniPrimary (citable) accession number: Q9LVQ8
Secondary accession number(s): Q3E849
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: October 1, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3