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Q9LVQ8

- P2C80_ARATH

UniProt

Q9LVQ8 - P2C80_ARATH

Protein

Probable protein phosphatase 2C 80

Gene

At5g66720

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi204 – 2041Manganese 1By similarity
    Metal bindingi204 – 2041Manganese 2By similarity
    Metal bindingi205 – 2051Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi336 – 3361Manganese 2By similarity
    Metal bindingi402 – 4021Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT5G66720-MONOMER.
    ARA:GQT-848-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 80 (EC:3.1.3.16)
    Short name:
    AtPP2C80
    Gene namesi
    Ordered Locus Names:At5g66720
    ORF Names:MSN2.11
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G66720.

    Subcellular locationi

    GO - Cellular componenti

    1. chloroplast Source: TAIR
    2. chloroplast stroma Source: TAIR

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 414414Probable protein phosphatase 2C 80PRO_0000367999Add
    BLAST

    Proteomic databases

    PaxDbiQ9LVQ8.
    PRIDEiQ9LVQ8.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9LVQ8.

    Interactioni

    Protein-protein interaction databases

    BioGridi22047. 12 interactions.
    IntActiQ9LVQ8. 12 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9LVQ8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini170 – 411242PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000239282.
    InParanoidiQ9LVQ8.
    KOiK17508.
    OMAiGSFTINC.
    PhylomeDBiQ9LVQ8.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9LVQ8-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSATALSRLN PVSQFGFQRI VAGKSKSFFS NSGQRRLFSD SSRFRQAMAA    50
    SGSLPVFGDA CLDDLVTTCS NGLDFTKKRS SGGSFTINCP VASMRLGKRG 100
    GMMKNRLVCH YSVVDPLEKS RALFGTLSKS VHTSPMACFS VGPAHELSSL 150
    NGGSQESPPT TTTSLKSLRL VSGSCYLPHP EKEATGGEDA HFICDEEQAI 200
    GVADGVGGWA EVGVNAGLFS RELMSYSVSA IQEQHKGSSI DPLVVLEKAH 250
    SQTKAKGSST ACIIVLKDKG LHAINLGDSG FTVVREGTTV FQSPVQQHGF 300
    NFTYQLESGN SADVPSSGQV FTIDVQSGDV IVAGTDGVYD NLYNEEITGV 350
    VVSSVRAGLD PKGTAQKIAE LARQRAVDKK RQSPFATAAQ EAGYRYYGGK 400
    LDDITAVVSY VTSS 414
    Length:414
    Mass (Da):43,873
    Last modified:October 1, 2000 - v1
    Checksum:i795E4D79381D5789
    GO
    Isoform 2 (identifier: Q9LVQ8-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         167-169: Missing.

    Note: May be due to a competing acceptor splice site. No experimental confirmation available.

    Show »
    Length:411
    Mass (Da):43,517
    Checksum:iFF894EE7D74F49E3
    GO

    Sequence cautioni

    The sequence BX833253 differs from that shown. Reason: Sequencing errors.

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei167 – 1693Missing in isoform 2. 1 PublicationVSP_036777

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB018119 Genomic DNA. Translation: BAA97278.1.
    CP002688 Genomic DNA. Translation: AED98255.1.
    CP002688 Genomic DNA. Translation: AED98256.1.
    AK117127 mRNA. Translation: BAC41805.1.
    AY136405 mRNA. Translation: AAM97071.1.
    BT000228 mRNA. Translation: AAN15547.1.
    BX833253 mRNA. No translation available.
    RefSeqiNP_201473.1. NM_126070.3. [Q9LVQ8-1]
    NP_975004.1. NM_203275.1. [Q9LVQ8-2]
    UniGeneiAt.28853.

    Genome annotation databases

    EnsemblPlantsiAT5G66720.1; AT5G66720.1; AT5G66720. [Q9LVQ8-1]
    GeneIDi836805.
    KEGGiath:AT5G66720.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB018119 Genomic DNA. Translation: BAA97278.1 .
    CP002688 Genomic DNA. Translation: AED98255.1 .
    CP002688 Genomic DNA. Translation: AED98256.1 .
    AK117127 mRNA. Translation: BAC41805.1 .
    AY136405 mRNA. Translation: AAM97071.1 .
    BT000228 mRNA. Translation: AAN15547.1 .
    BX833253 mRNA. No translation available.
    RefSeqi NP_201473.1. NM_126070.3. [Q9LVQ8-1 ]
    NP_975004.1. NM_203275.1. [Q9LVQ8-2 ]
    UniGenei At.28853.

    3D structure databases

    ProteinModelPortali Q9LVQ8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 22047. 12 interactions.
    IntActi Q9LVQ8. 12 interactions.

    Proteomic databases

    PaxDbi Q9LVQ8.
    PRIDEi Q9LVQ8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G66720.1 ; AT5G66720.1 ; AT5G66720 . [Q9LVQ8-1 ]
    GeneIDi 836805.
    KEGGi ath:AT5G66720.

    Organism-specific databases

    TAIRi AT5G66720.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000239282.
    InParanoidi Q9LVQ8.
    KOi K17508.
    OMAi GSFTINC.
    PhylomeDBi Q9LVQ8.

    Enzyme and pathway databases

    BioCyci ARA:AT5G66720-MONOMER.
    ARA:GQT-848-MONOMER.

    Gene expression databases

    Genevestigatori Q9LVQ8.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones."
      Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H., Tabata S.
      DNA Res. 7:31-63(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Strain: cv. Columbia.
    4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Strain: cv. Columbia.
    5. "Whole genome sequence comparisons and 'full-length' cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation."
      Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M., Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M., Weissenbach J., Salanoubat M.
      Genome Res. 14:406-413(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Strain: cv. Columbia.
    6. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C80_ARATH
    AccessioniPrimary (citable) accession number: Q9LVQ8
    Secondary accession number(s): Q3E849
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3