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Q9LVQ8 (P2C80_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 80

Short name=AtPP2C80
EC=3.1.3.16
Gene names
Ordered Locus Names:At5g66720
ORF Names:MSN2.11
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length414 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Sequence caution

The sequence BX833253 differs from that shown. Reason: Sequencing errors.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9LVQ8-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9LVQ8-2)

The sequence of this isoform differs from the canonical sequence as follows:
     167-169: Missing.
Note: May be due to a competing acceptor splice site. No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 414414Probable protein phosphatase 2C 80
PRO_0000367999

Regions

Domain170 – 411242PP2C-like

Sites

Metal binding2041Manganese 1 By similarity
Metal binding2041Manganese 2 By similarity
Metal binding2051Manganese 1; via carbonyl oxygen By similarity
Metal binding3361Manganese 2 By similarity
Metal binding4021Manganese 2 By similarity

Natural variations

Alternative sequence167 – 1693Missing in isoform 2.
VSP_036777

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 795E4D79381D5789

FASTA41443,873
        10         20         30         40         50         60 
MSATALSRLN PVSQFGFQRI VAGKSKSFFS NSGQRRLFSD SSRFRQAMAA SGSLPVFGDA 

        70         80         90        100        110        120 
CLDDLVTTCS NGLDFTKKRS SGGSFTINCP VASMRLGKRG GMMKNRLVCH YSVVDPLEKS 

       130        140        150        160        170        180 
RALFGTLSKS VHTSPMACFS VGPAHELSSL NGGSQESPPT TTTSLKSLRL VSGSCYLPHP 

       190        200        210        220        230        240 
EKEATGGEDA HFICDEEQAI GVADGVGGWA EVGVNAGLFS RELMSYSVSA IQEQHKGSSI 

       250        260        270        280        290        300 
DPLVVLEKAH SQTKAKGSST ACIIVLKDKG LHAINLGDSG FTVVREGTTV FQSPVQQHGF 

       310        320        330        340        350        360 
NFTYQLESGN SADVPSSGQV FTIDVQSGDV IVAGTDGVYD NLYNEEITGV VVSSVRAGLD 

       370        380        390        400        410 
PKGTAQKIAE LARQRAVDKK RQSPFATAAQ EAGYRYYGGK LDDITAVVSY VTSS 

« Hide

Isoform 2 [UniParc].

Checksum: FF894EE7D74F49E3
Show »

FASTA41143,517

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones."
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H., Tabata S.
DNA Res. 7:31-63(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Functional annotation of a full-length Arabidopsis cDNA collection."
Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K.
Science 296:141-145(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Strain: cv. Columbia.
[5]"Whole genome sequence comparisons and 'full-length' cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation."
Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M., Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M., Weissenbach J., Salanoubat M.
Genome Res. 14:406-413(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Strain: cv. Columbia.
[6]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB018119 Genomic DNA. Translation: BAA97278.1.
CP002688 Genomic DNA. Translation: AED98255.1.
CP002688 Genomic DNA. Translation: AED98256.1.
AK117127 mRNA. Translation: BAC41805.1.
AY136405 mRNA. Translation: AAM97071.1.
BT000228 mRNA. Translation: AAN15547.1.
BX833253 mRNA. No translation available.
RefSeqNP_201473.1. NM_126070.3. [Q9LVQ8-1]
NP_975004.1. NM_203275.1. [Q9LVQ8-2]
UniGeneAt.28853.

3D structure databases

ProteinModelPortalQ9LVQ8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid22047. 12 interactions.
IntActQ9LVQ8. 12 interactions.

Proteomic databases

PaxDbQ9LVQ8.
PRIDEQ9LVQ8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G66720.1; AT5G66720.1; AT5G66720. [Q9LVQ8-1]
GeneID836805.
KEGGath:AT5G66720.

Organism-specific databases

TAIRAT5G66720.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000239282.
InParanoidQ9LVQ8.
KOK17508.
OMAGSFTINC.
PhylomeDBQ9LVQ8.

Enzyme and pathway databases

BioCycARA:AT5G66720-MONOMER.
ARA:GQT-848-MONOMER.

Gene expression databases

GenevestigatorQ9LVQ8.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 1 hit.
ProtoNetSearch...

Entry information

Entry nameP2C80_ARATH
AccessionPrimary (citable) accession number: Q9LVQ8
Secondary accession number(s): Q3E849
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names