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Q9LV37 (MPK9_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mitogen-activated protein kinase 9

Short name=AtMPK9
Short name=MAP kinase 9
EC=2.7.11.24
Gene names
Name:MPK9
Ordered Locus Names:At3g18040
ORF Names:MRC8.2, MRC8.4
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length510 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulation

Activated by threonine and tyrosine phosphorylation By similarity.

Domain

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Post-translational modification

Dually phosphorylated on Thr-185 and Tyr-187, which activates the enzyme By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

Contains 1 protein kinase domain.

Sequence caution

The sequence BAB02016.1 differs from that shown. Reason: Erroneous initiation.

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q9LV37-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 510510Mitogen-activated protein kinase 9
PRO_0000245809

Regions

Domain23 – 314292Protein kinase
Nucleotide binding29 – 379ATP By similarity
Motif185 – 1873TXY

Sites

Active site1491Proton acceptor By similarity
Binding site521ATP By similarity

Amino acid modifications

Modified residue1851Phosphothreonine By similarity
Modified residue1871Phosphotyrosine By similarity
Modified residue1901Phosphothreonine By similarity

Experimental info

Sequence conflict461G → C in BAA92223. Ref.1
Sequence conflict541I → S in BAA92223. Ref.1
Sequence conflict961E → D in BAA92223. Ref.1
Sequence conflict1901T → N in BAA92223. Ref.1
Sequence conflict3411I → L in BAA92223. Ref.1
Sequence conflict4611T → Q in BAA92223. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified July 11, 2006. Version 2.
Checksum: 6E41FB646C3C7F12

FASTA51058,395
        10         20         30         40         50         60 
MDPHKKVALE TEFFTEYGEA SRYQIQEVIG KGSYGVVASA IDTHSGEKVA IKKINDVFEH 

        70         80         90        100        110        120 
VSDATRILRE IKLLRLLRHP DIVEIKHVML PPSRREFRDI YVVFELMESD LHQVIKANDD 

       130        140        150        160        170        180 
LTPEHYQFFL YQLLRGLKFI HTANVFHRDL KPKNILANSD CKLKICDFGL ARVSFNDAPS 

       190        200        210        220        230        240 
AIFWTDYVAT RWYRAPELCG SFFSKYTPAI DIWSIGCIFA EMLTGKPLFP GKNVVHQLDI 

       250        260        270        280        290        300 
MTDLLGTPPP EAIARIRNEK ARRYLGNMRR KPPVPFTHKF PHVDPLALRL LHRLLAFDPK 

       310        320        330        340        350        360 
DRPSAEEALA DPYFYGLANV DREPSTQPIP KLEFEFERRK ITKEDVRELI YREILEYHPQ 

       370        380        390        400        410        420 
MLQEYLRGGE QTSFMYPSGV DRFKRQFAHL EENYGKGEKG SPLQRQHASL PRERVPAPKK 

       430        440        450        460        470        480 
ENGSHNHDIE NRSIASLVTT LESPPTSQHE GSDYRNGTSQ TGYSARSLLK SASISASKCI 

       490        500        510 
GMKPRNKSEY GESNNDTVDA LSQKVAALHT 

« Hide

References

« Hide 'large scale' references
[1]"Arabidopsis thaliana mRNA for MAP kinase."
Mizoguchi T., Ichimura K., Shinozaki K.
Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
[2]"Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.
DNA Res. 7:217-221(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Mitogen-activated protein kinase cascades in plants: a new nomenclature."
MAPK group
Trends Plant Sci. 7:301-308(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[5]"Ancient signals: comparative genomics of plant MAPK and MAPKK gene families."
Hamel L.P., Nicole M.C., Sritubtim S., Morency M.J., Ellis M., Ehlting J., Beaudoin N., Barbazuk B., Klessig D., Lee J., Martin G., Mundy J., Ohashi Y., Scheel D., Sheen J., Xing T., Zhang S., Seguin A., Ellis B.E.
Trends Plant Sci. 11:192-198(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB038694 mRNA. Translation: BAA92223.1.
AB020749 Genomic DNA. Translation: BAB02016.1. Different initiation.
CP002686 Genomic DNA. Translation: AEE76038.1.
RefSeqNP_566595.1. NM_112686.4. [Q9LV37-1]
UniGeneAt.471.

3D structure databases

ProteinModelPortalQ9LV37.
SMRQ9LV37. Positions 23-360.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-8060599.
STRING3702.AT3G18040.1-P.

Proteomic databases

PaxDbQ9LV37.
PRIDEQ9LV37.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G18040.1; AT3G18040.1; AT3G18040. [Q9LV37-1]
GeneID821329.
KEGGath:AT3G18040.

Organism-specific databases

GeneFarm865. 89.
TAIRAT3G18040.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000233024.
InParanoidQ9LV37.
OMAKENGSHN.
PhylomeDBQ9LV37.

Enzyme and pathway databases

BioCycARA:AT3G18040-MONOMER.
ARA:GQT-1685-MONOMER.

Gene expression databases

ArrayExpressQ9LV37.
GenevestigatorQ9LV37.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMPK9_ARATH
AccessionPrimary (citable) accession number: Q9LV37
Secondary accession number(s): Q9MB22
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: July 11, 2006
Last modified: June 11, 2014
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names