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Q9LV37

- MPK9_ARATH

UniProt

Q9LV37 - MPK9_ARATH

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Protein

Mitogen-activated protein kinase 9

Gene
MPK9, At3g18040, MRC8.2, MRC8.4
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulationi

Activated by threonine and tyrosine phosphorylation By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei52 – 521ATP By similarity
Active sitei149 – 1491Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi29 – 379ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. MAP kinase activity Source: TAIR

GO - Biological processi

  1. abscisic acid-activated signaling pathway Source: TAIR
  2. MAPK cascade Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT3G18040-MONOMER.
ARA:GQT-1685-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinase 9 (EC:2.7.11.24)
Short name:
AtMPK9
Short name:
MAP kinase 9
Gene namesi
Name:MPK9
Ordered Locus Names:At3g18040
ORF Names:MRC8.2, MRC8.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 3

Organism-specific databases

TAIRiAT3G18040.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: TAIR
  2. mitochondrion Source: TAIR
  3. nucleus Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 510510Mitogen-activated protein kinase 9PRO_0000245809Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei185 – 1851Phosphothreonine By similarity
Modified residuei187 – 1871Phosphotyrosine By similarity
Modified residuei190 – 1901Phosphothreonine By similarity

Post-translational modificationi

Dually phosphorylated on Thr-185 and Tyr-187, which activates the enzyme By similarity.

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9LV37.
PRIDEiQ9LV37.

Expressioni

Gene expression databases

ArrayExpressiQ9LV37.
GenevestigatoriQ9LV37.

Interactioni

Protein-protein interaction databases

MINTiMINT-8060599.
STRINGi3702.AT3G18040.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9LV37.
SMRiQ9LV37. Positions 23-360.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 314292Protein kinaseAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi185 – 1873TXY

Domaini

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
InParanoidiQ9LV37.
OMAiKENGSHN.
PhylomeDBiQ9LV37.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. Align

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q9LV37-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MDPHKKVALE TEFFTEYGEA SRYQIQEVIG KGSYGVVASA IDTHSGEKVA    50
IKKINDVFEH VSDATRILRE IKLLRLLRHP DIVEIKHVML PPSRREFRDI 100
YVVFELMESD LHQVIKANDD LTPEHYQFFL YQLLRGLKFI HTANVFHRDL 150
KPKNILANSD CKLKICDFGL ARVSFNDAPS AIFWTDYVAT RWYRAPELCG 200
SFFSKYTPAI DIWSIGCIFA EMLTGKPLFP GKNVVHQLDI MTDLLGTPPP 250
EAIARIRNEK ARRYLGNMRR KPPVPFTHKF PHVDPLALRL LHRLLAFDPK 300
DRPSAEEALA DPYFYGLANV DREPSTQPIP KLEFEFERRK ITKEDVRELI 350
YREILEYHPQ MLQEYLRGGE QTSFMYPSGV DRFKRQFAHL EENYGKGEKG 400
SPLQRQHASL PRERVPAPKK ENGSHNHDIE NRSIASLVTT LESPPTSQHE 450
GSDYRNGTSQ TGYSARSLLK SASISASKCI GMKPRNKSEY GESNNDTVDA 500
LSQKVAALHT 510
Length:510
Mass (Da):58,395
Last modified:July 11, 2006 - v2
Checksum:i6E41FB646C3C7F12
GO

Sequence cautioni

The sequence BAB02016.1 differs from that shown. Reason: Erroneous initiation.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti46 – 461G → C in BAA92223. 1 Publication
Sequence conflicti54 – 541I → S in BAA92223. 1 Publication
Sequence conflicti96 – 961E → D in BAA92223. 1 Publication
Sequence conflicti190 – 1901T → N in BAA92223. 1 Publication
Sequence conflicti341 – 3411I → L in BAA92223. 1 Publication
Sequence conflicti461 – 4611T → Q in BAA92223. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB038694 mRNA. Translation: BAA92223.1.
AB020749 Genomic DNA. Translation: BAB02016.1. Different initiation.
CP002686 Genomic DNA. Translation: AEE76038.1.
RefSeqiNP_566595.1. NM_112686.4. [Q9LV37-1]
UniGeneiAt.471.

Genome annotation databases

EnsemblPlantsiAT3G18040.1; AT3G18040.1; AT3G18040. [Q9LV37-1]
GeneIDi821329.
KEGGiath:AT3G18040.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB038694 mRNA. Translation: BAA92223.1 .
AB020749 Genomic DNA. Translation: BAB02016.1 . Different initiation.
CP002686 Genomic DNA. Translation: AEE76038.1 .
RefSeqi NP_566595.1. NM_112686.4. [Q9LV37-1 ]
UniGenei At.471.

3D structure databases

ProteinModelPortali Q9LV37.
SMRi Q9LV37. Positions 23-360.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-8060599.
STRINGi 3702.AT3G18040.1-P.

Proteomic databases

PaxDbi Q9LV37.
PRIDEi Q9LV37.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT3G18040.1 ; AT3G18040.1 ; AT3G18040 . [Q9LV37-1 ]
GeneIDi 821329.
KEGGi ath:AT3G18040.

Organism-specific databases

GeneFarmi 865. 89.
TAIRi AT3G18040.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000233024.
InParanoidi Q9LV37.
OMAi KENGSHN.
PhylomeDBi Q9LV37.

Enzyme and pathway databases

BioCyci ARA:AT3G18040-MONOMER.
ARA:GQT-1685-MONOMER.

Gene expression databases

ArrayExpressi Q9LV37.
Genevestigatori Q9LV37.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Arabidopsis thaliana mRNA for MAP kinase."
    Mizoguchi T., Ichimura K., Shinozaki K.
    Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Columbia.
  2. "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
    Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.
    DNA Res. 7:217-221(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Mitogen-activated protein kinase cascades in plants: a new nomenclature."
    MAPK group
    Trends Plant Sci. 7:301-308(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.
  5. Cited for: GENE FAMILY.

Entry informationi

Entry nameiMPK9_ARATH
AccessioniPrimary (citable) accession number: Q9LV37
Secondary accession number(s): Q9MB22
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: July 11, 2006
Last modified: June 11, 2014
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi