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Q9LV34

- BGL43_ARATH

UniProt

Q9LV34 - BGL43_ARATH

Protein

Beta-glucosidase 43

Gene

BGLU43

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 2 (15 Dec 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei49 – 491SubstrateBy similarity
    Binding sitei150 – 1501SubstrateBy similarity
    Binding sitei193 – 1931SubstrateBy similarity
    Active sitei194 – 1941Proton donorBy similarity
    Binding sitei336 – 3361SubstrateBy similarity
    Active sitei408 – 4081NucleophileBy similarity
    Binding sitei455 – 4551SubstrateBy similarity

    GO - Molecular functioni

    1. beta-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Enzyme and pathway databases

    BioCyciARA:AT3G18070-MONOMER.
    ARA:GQT-414-MONOMER.

    Protein family/group databases

    CAZyiGH1. Glycoside Hydrolase Family 1.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-glucosidase 43 (EC:3.2.1.21)
    Short name:
    AtBGLU43
    Gene namesi
    Name:BGLU43
    Ordered Locus Names:At3g18070
    ORF Names:MRC8.6
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G18070.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1414Sequence AnalysisAdd
    BLAST
    Chaini15 – 501487Beta-glucosidase 43PRO_0000390316Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi77 – 771N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi213 ↔ 220By similarity
    Glycosylationi219 – 2191N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi360 – 3601N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi416 – 4161N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi424 – 4241N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi448 – 4481N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiQ9LV34.
    PRIDEiQ9LV34.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9LV34.
    SMRiQ9LV34. Positions 28-496.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni462 – 4632Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 1 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG2723.
    HOGENOMiHOG000088630.
    InParanoidiQ1PEP7.
    OMAiIDNINEP.
    PhylomeDBiQ9LV34.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR001360. Glyco_hydro_1.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR10353. PTHR10353. 1 hit.
    PfamiPF00232. Glyco_hydro_1. 1 hit.
    [Graphical view]
    PRINTSiPR00131. GLHYDRLASE1.
    SUPFAMiSSF51445. SSF51445. 1 hit.

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9LV34-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MFLFLLLLSA SRSGEESPSG DAVPLATGGL NRKSFPEGFL FGTATSAYQV    50
    EGETHQDGRG PSIWDAFVKI PGKIANNATA EITVDQYHRY KEDVDLMQNL 100
    NIDAYRFSIS WSRIFPEGSG KINSNGVAYY NRLIDYLIEK GITPYANLYH 150
    YDLPLALEQK YQGLLSKQGR FCGLRRVLFQ TFGDRVKNWM TFNEPRVVAA 200
    LGYDNGIFAP GRCSEAFGNC TDGNSATEPY IVAHHLILAH AAAVQRYRQN 250
    YQEKQKGRVG ILLDFVWFEP LTSSQADNDA AQRARDFHVG WFIHPIVYGE 300
    YPNTLQNIVK ERLPKFTEEE VKMVKGSIDF VGINQYTTYF MSDPKISTTP 350
    KDLGYQQDWN VTFNFAKNGT PIGPRAHSEW LYNVPWGMYK ALMYIEERYG 400
    NPTMILSENG MDDPGNITLT QGLNDTTRVK YYRDYLVQLK KAVDDGANLT 450
    GYFAWSLLDN FEWLSGYTSR FGIVYVDYKD LKRYPKMSAL WFKQLLKRDQ 500
    K 501

    Note: Derived from EST data. No experimental confirmation available.

    Length:501
    Mass (Da):57,244
    Last modified:December 15, 2009 - v2
    Checksum:i755B6F26B32B481E
    GO
    Isoform 2 (identifier: Q9LV34-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         92-168: Missing.

    Show »
    Length:424
    Mass (Da):48,313
    Checksum:i552610A1B3A40EF5
    GO

    Sequence cautioni

    The sequence BAB02019.1 differs from that shown. Reason: Erroneous gene model prediction.

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei92 – 16877Missing in isoform 2. 1 PublicationVSP_038500Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB020749 Genomic DNA. Translation: BAB02019.1. Sequence problems.
    CP002686 Genomic DNA. Translation: AEE76042.1.
    CP002686 Genomic DNA. Translation: AEE76043.1.
    DQ446670 mRNA. Translation: ABE65945.1.
    RefSeqiNP_001078176.1. NM_001084707.1. [Q9LV34-2]
    NP_188435.2. NM_112689.2. [Q9LV34-1]
    UniGeneiAt.53364.

    Genome annotation databases

    EnsemblPlantsiAT3G18070.1; AT3G18070.1; AT3G18070. [Q9LV34-1]
    GeneIDi821332.
    KEGGiath:AT3G18070.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB020749 Genomic DNA. Translation: BAB02019.1 . Sequence problems.
    CP002686 Genomic DNA. Translation: AEE76042.1 .
    CP002686 Genomic DNA. Translation: AEE76043.1 .
    DQ446670 mRNA. Translation: ABE65945.1 .
    RefSeqi NP_001078176.1. NM_001084707.1. [Q9LV34-2 ]
    NP_188435.2. NM_112689.2. [Q9LV34-1 ]
    UniGenei At.53364.

    3D structure databases

    ProteinModelPortali Q9LV34.
    SMRi Q9LV34. Positions 28-496.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH1. Glycoside Hydrolase Family 1.

    Proteomic databases

    PaxDbi Q9LV34.
    PRIDEi Q9LV34.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G18070.1 ; AT3G18070.1 ; AT3G18070 . [Q9LV34-1 ]
    GeneIDi 821332.
    KEGGi ath:AT3G18070.

    Organism-specific databases

    TAIRi AT3G18070.

    Phylogenomic databases

    eggNOGi COG2723.
    HOGENOMi HOG000088630.
    InParanoidi Q1PEP7.
    OMAi IDNINEP.
    PhylomeDBi Q9LV34.

    Enzyme and pathway databases

    BioCyci ARA:AT3G18070-MONOMER.
    ARA:GQT-414-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR001360. Glyco_hydro_1.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR10353. PTHR10353. 1 hit.
    Pfami PF00232. Glyco_hydro_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00131. GLHYDRLASE1.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
      Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.
      DNA Res. 7:217-221(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations."
      Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.
      Plant Biotechnol. J. 4:317-324(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Strain: cv. Columbia.
    4. Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiBGL43_ARATH
    AccessioniPrimary (citable) accession number: Q9LV34
    Secondary accession number(s): Q1PEP7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 2009
    Last sequence update: December 15, 2009
    Last modified: October 1, 2014
    This is version 76 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3