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Protein

ATPase 11, plasma membrane-type

Gene

AHA11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

The plasma membrane H+ ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H+-symport. The resulting external acidification and/or internal alkinization may mediate growth responses (By similarity).By similarity

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei3334-aspartylphosphate intermediateBy similarity1
Metal bindingi592MagnesiumBy similarity1
Metal bindingi596MagnesiumBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Hydrogen ion transport, Ion transport, Transport

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT5G62670-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ATPase 11, plasma membrane-type (EC:3.6.3.6)
Alternative name(s):
Proton pump 11
Gene namesi
Name:AHA11
Ordered Locus Names:At5g62670
ORF Names:MRG21.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G62670.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 65CytoplasmicSequence analysisAdd BLAST65
Transmembranei66 – 85Helical; Name=1Sequence analysisAdd BLAST20
Topological domaini86 – 97ExtracellularSequence analysisAdd BLAST12
Transmembranei98 – 118Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini119 – 247CytoplasmicSequence analysisAdd BLAST129
Transmembranei248 – 268Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini269 – 277ExtracellularSequence analysis9
Transmembranei278 – 295Helical; Name=4Sequence analysisAdd BLAST18
Topological domaini296 – 647CytoplasmicSequence analysisAdd BLAST352
Transmembranei648 – 669Helical; Name=5Sequence analysisAdd BLAST22
Topological domaini670 – 674ExtracellularSequence analysis5
Transmembranei675 – 697Helical; Name=6Sequence analysisAdd BLAST23
Topological domaini698 – 713CytoplasmicSequence analysisAdd BLAST16
Transmembranei714 – 734Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini735 – 759ExtracellularSequence analysisAdd BLAST25
Transmembranei760 – 780Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini781 – 792CytoplasmicSequence analysisAdd BLAST12
Transmembranei793 – 813Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini814 – 821ExtracellularSequence analysis8
Transmembranei822 – 842Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini843 – 956CytoplasmicSequence analysisAdd BLAST114

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • intracellular membrane-bounded organelle Source: GO_Central
  • membrane Source: TAIR
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000462841 – 956ATPase 11, plasma membrane-typeAdd BLAST956

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei889PhosphothreonineCombined sources1
Modified residuei938PhosphoserineBy similarity1
Modified residuei955PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9LV11.
PRIDEiQ9LV11.

PTM databases

iPTMnetiQ9LV11.

Expressioni

Gene expression databases

ExpressionAtlasiQ9LV11. baseline and differential.
GenevisibleiQ9LV11. AT.

Interactioni

Subunit structurei

Binds to 14-3-3 proteins. The binding is induced by phosphorylation of Thr-955. Binding to 14-3-3 proteins activates the H+-ATPase (By similarity).By similarity

Protein-protein interaction databases

BioGridi21631. 1 interactor.
STRINGi3702.AT5G62670.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LV11.
SMRiQ9LV11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni954 – 956Interaction with 14-3-3 proteinsBy similarity3

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0205. Eukaryota.
COG0474. LUCA.
HOGENOMiHOG000160005.
InParanoidiQ9LV11.
KOiK01535.
OMAiHLAHNKP.
OrthoDBiEOG093601UL.
PhylomeDBiQ9LV11.

Family and domain databases

Gene3Di1.20.1110.10. 3 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProiIPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006534. P-type_ATPase_IIIA.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
PRINTSiPR00120. HATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
TIGRFAMsiTIGR01647. ATPase-IIIA_H. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LV11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGDKEEVLEA VLKETVDLEN VPIEEVFESL RCSREGLTTE AADERLALFG
60 70 80 90 100
HNKLEEKKES KFLKFLGFMW NPLSWVMEAA AIMAIALANG GGKPPDWQDF
110 120 130 140 150
VGIITLLVIN STISFIEENN AGNAAAALMA RLAPKAKVLR DGRWGEQDAA
160 170 180 190 200
ILVPGDIISI KLGDIVPADA RLLEGDPLKI DQSSLTGESL PVTKGPGDGV
210 220 230 240 250
YSGSTCKQGE LEAVVIATGV HTFFGKAAHL VDTTNHVGHF QQVLTAIGNF
260 270 280 290 300
CICSIAVGMI IEIVVMYPIQ HRAYRPGIDN LLVLLIGGIP IAMPTVLSVT
310 320 330 340 350
MAIGSHRLSQ QGAITKRMTA IEEMAGMDVL CSDKTGTLTL NKLTVDKNLI
360 370 380 390 400
EVFTKGVDAD TVVLMAAQAS RLENQDAIDA AIVGMLADPK EARAGVREVH
410 420 430 440 450
FLPFNPTDKR TALTYIDSDG KMHRVSKGAP EQILNLAHNR AEIERRVHAV
460 470 480 490 500
IDKFAERGLR SLAVAYQEVP EGTKESAGGP WQFMGLMPLF DPPRHDSAET
510 520 530 540 550
IRRALNLGVN VKMITGDQLA IGKETGRRLG MGTNMYPSSA LLGQHKDESI
560 570 580 590 600
GALPIDDLIE KADGFAGVFP EHKYEIVKRL QARKHICGMT GDGVNDAPAL
610 620 630 640 650
KKADIGIAVA DATDAARSAS DIVLTEPGLS VIISAVLTSR AIFQRMKNYT
660 670 680 690 700
IYAVSITIRI VLGFMLLALI WKFDFPPFMV LIIAILNDGT IMTISKDRVK
710 720 730 740 750
PSPLPDSWKL SEIFATGVVF GSYMAMMTVI FFWAAYKTDF FPRTFGVSTL
760 770 780 790 800
EKTAHDDFRK LASAIYLQVS IISQALIFVT RSRSWSYVER PGMLLVVAFI
810 820 830 840 850
LAQLVATLIA VYANWSFAAI EGIGWGWAGV IWLYNIVFYI PLDIIKFLIR
860 870 880 890 900
YALSGRAWDL VIEQRVAFTR QKDFGKEQRE LQWAHAQRTL HGLQAPDAKM
910 920 930 940 950
FPERTHFNEL SQMAEEAKRR AEIARLRELH TLKGHVESVV RLKGLDIETI

QQAYTV
Length:956
Mass (Da):105,123
Last modified:October 1, 2000 - v1
Checksum:iCA59212B16B9C5BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020751 Genomic DNA. Translation: BAA97214.1.
CP002688 Genomic DNA. Translation: AED97641.1.
AY125493 mRNA. Translation: AAM78085.1.
RefSeqiNP_201073.1. NM_125662.4.
UniGeneiAt.28239.
At.68527.

Genome annotation databases

EnsemblPlantsiAT5G62670.1; AT5G62670.1; AT5G62670.
GeneIDi836388.
GrameneiAT5G62670.1; AT5G62670.1; AT5G62670.
KEGGiath:AT5G62670.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020751 Genomic DNA. Translation: BAA97214.1.
CP002688 Genomic DNA. Translation: AED97641.1.
AY125493 mRNA. Translation: AAM78085.1.
RefSeqiNP_201073.1. NM_125662.4.
UniGeneiAt.28239.
At.68527.

3D structure databases

ProteinModelPortaliQ9LV11.
SMRiQ9LV11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi21631. 1 interactor.
STRINGi3702.AT5G62670.1.

PTM databases

iPTMnetiQ9LV11.

Proteomic databases

PaxDbiQ9LV11.
PRIDEiQ9LV11.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G62670.1; AT5G62670.1; AT5G62670.
GeneIDi836388.
GrameneiAT5G62670.1; AT5G62670.1; AT5G62670.
KEGGiath:AT5G62670.

Organism-specific databases

TAIRiAT5G62670.

Phylogenomic databases

eggNOGiKOG0205. Eukaryota.
COG0474. LUCA.
HOGENOMiHOG000160005.
InParanoidiQ9LV11.
KOiK01535.
OMAiHLAHNKP.
OrthoDBiEOG093601UL.
PhylomeDBiQ9LV11.

Enzyme and pathway databases

BioCyciARA:AT5G62670-MONOMER.

Miscellaneous databases

PROiQ9LV11.

Gene expression databases

ExpressionAtlasiQ9LV11. baseline and differential.
GenevisibleiQ9LV11. AT.

Family and domain databases

Gene3Di1.20.1110.10. 3 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProiIPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006534. P-type_ATPase_IIIA.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
PRINTSiPR00120. HATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
TIGRFAMsiTIGR01647. ATPase-IIIA_H. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPMA11_ARATH
AccessioniPrimary (citable) accession number: Q9LV11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 133 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.