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Q9LUU7

- P2C43_ARATH

UniProt

Q9LUU7 - P2C43_ARATH

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Protein

Probable protein phosphatase 2C 43

Gene

At3g17250

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi163 – 1631Manganese 1By similarity
Metal bindingi163 – 1631Manganese 2By similarity
Metal bindingi164 – 1641Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi341 – 3411Manganese 2By similarity
Metal bindingi384 – 3841Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT3G17250-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 43 (EC:3.1.3.16)
Short name:
AtPP2C43
Gene namesi
Ordered Locus Names:At3g17250
ORF Names:MGD8.13, MGD8.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 3

Organism-specific databases

TAIRiAT3G17250.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 422422Probable protein phosphatase 2C 43PRO_0000367967Add
BLAST

Proteomic databases

PaxDbiQ9LUU7.
PRIDEiQ9LUU7.

Expressioni

Gene expression databases

GenevestigatoriQ9LUU7.

Interactioni

Protein-protein interaction databases

BioGridi6319. 1 interaction.
IntActiQ9LUU7. 1 interaction.
MINTiMINT-8390632.

Structurei

3D structure databases

ProteinModelPortaliQ9LUU7.
SMRiQ9LUU7. Positions 95-393.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini117 – 386270PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ9LUU7.
KOiK14803.
OMAiRHLMVAN.
PhylomeDBiQ9LUU7.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LUU7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRTSKASVTQ TWLLYTQLCL WKDLIIRYVR QIIRRAKSML FSQNMVADSA
60 70 80 90 100
EISVIDVKSH LSVAKDPSNF QIAEIRIHDS ICIDIPSSEE TPLLESIKSC
110 120 130 140 150
SATTIEEHVT EFVPNISSGS YADKGDYREY MEDEHICIDD LSDHLGSSFY
160 170 180 190 200
RFPVPMAFYG VFDGHGGSDA SQYIKENAMS LFFEDAVFRQ SPSVVDSLFL
210 220 230 240 250
KELETSHREA YRLADLAMED ERIVSSSCGT TALTALVIGR HLMVANVGDC
260 270 280 290 300
RAVLCRKGKA VDMSFDHKST FEPERRRVED LGGYFEGEYL YGDLAVTRAL
310 320 330 340 350
GDWSIKRFSP LGESLSPLIS DPDIQQMILT EEDEFLIMGC DGVWDVMTSQ
360 370 380 390 400
YAVTFVRQGL RRHGDPRRCA MELGREALRL DSSDNVTVVV ICFSSSPAPQ
410 420
RRRIRFCVSD EARARLQTML EG
Length:422
Mass (Da):47,599
Last modified:October 1, 2000 - v1
Checksum:i63B7B3E7DD69FCE4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti303 – 3031W → S in BAD94223. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB022216 Genomic DNA. Translation: BAB02728.1.
CP002686 Genomic DNA. Translation: AEE75928.1.
AK220861 mRNA. Translation: BAD94223.1.
AK228860 mRNA. Translation: BAF00754.1.
RefSeqiNP_188351.2. NM_112603.2.
UniGeneiAt.38757.

Genome annotation databases

EnsemblPlantsiAT3G17250.1; AT3G17250.1; AT3G17250.
GeneIDi820986.
KEGGiath:AT3G17250.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB022216 Genomic DNA. Translation: BAB02728.1 .
CP002686 Genomic DNA. Translation: AEE75928.1 .
AK220861 mRNA. Translation: BAD94223.1 .
AK228860 mRNA. Translation: BAF00754.1 .
RefSeqi NP_188351.2. NM_112603.2.
UniGenei At.38757.

3D structure databases

ProteinModelPortali Q9LUU7.
SMRi Q9LUU7. Positions 95-393.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 6319. 1 interaction.
IntActi Q9LUU7. 1 interaction.
MINTi MINT-8390632.

Proteomic databases

PaxDbi Q9LUU7.
PRIDEi Q9LUU7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT3G17250.1 ; AT3G17250.1 ; AT3G17250 .
GeneIDi 820986.
KEGGi ath:AT3G17250.

Organism-specific databases

TAIRi AT3G17250.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000233896.
InParanoidi Q9LUU7.
KOi K14803.
OMAi RHLMVAN.
PhylomeDBi Q9LUU7.

Enzyme and pathway databases

BioCyci ARA:AT3G17250-MONOMER.

Gene expression databases

Genevestigatori Q9LUU7.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
    Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
    DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C43_ARATH
AccessioniPrimary (citable) accession number: Q9LUU7
Secondary accession number(s): Q56ZV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: October 29, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3