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Protein

Probable protein phosphatase 2C 43

Gene

At3g17250

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi163Manganese 1By similarity1
Metal bindingi163Manganese 2By similarity1
Metal bindingi164Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi341Manganese 2By similarity1
Metal bindingi384Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 43 (EC:3.1.3.16)
Short name:
AtPP2C43
Gene namesi
Ordered Locus Names:At3g17250
ORF Names:MGD8.13, MGD8.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G17250
TAIRilocus:2089035 AT3G17250

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679671 – 422Probable protein phosphatase 2C 43Add BLAST422

Proteomic databases

PaxDbiQ9LUU7

Expressioni

Gene expression databases

ExpressionAtlasiQ9LUU7 baseline and differential
GenevisibleiQ9LUU7 AT

Interactioni

Protein-protein interaction databases

BioGridi6319, 1 interactor
IntActiQ9LUU7, 1 interactor
MINTiQ9LUU7
STRINGi3702.AT3G17250.1

Structurei

3D structure databases

ProteinModelPortaliQ9LUU7
SMRiQ9LUU7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini117 – 393PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST277

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
HOGENOMiHOG000233896
InParanoidiQ9LUU7
KOiK14803
OMAiIAEIRIH
OrthoDBiEOG09360E05
PhylomeDBiQ9LUU7

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR000222 PP2C_BS
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS01032 PPM_1, 1 hit
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LUU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTSKASVTQ TWLLYTQLCL WKDLIIRYVR QIIRRAKSML FSQNMVADSA
60 70 80 90 100
EISVIDVKSH LSVAKDPSNF QIAEIRIHDS ICIDIPSSEE TPLLESIKSC
110 120 130 140 150
SATTIEEHVT EFVPNISSGS YADKGDYREY MEDEHICIDD LSDHLGSSFY
160 170 180 190 200
RFPVPMAFYG VFDGHGGSDA SQYIKENAMS LFFEDAVFRQ SPSVVDSLFL
210 220 230 240 250
KELETSHREA YRLADLAMED ERIVSSSCGT TALTALVIGR HLMVANVGDC
260 270 280 290 300
RAVLCRKGKA VDMSFDHKST FEPERRRVED LGGYFEGEYL YGDLAVTRAL
310 320 330 340 350
GDWSIKRFSP LGESLSPLIS DPDIQQMILT EEDEFLIMGC DGVWDVMTSQ
360 370 380 390 400
YAVTFVRQGL RRHGDPRRCA MELGREALRL DSSDNVTVVV ICFSSSPAPQ
410 420
RRRIRFCVSD EARARLQTML EG
Length:422
Mass (Da):47,599
Last modified:October 1, 2000 - v1
Checksum:i63B7B3E7DD69FCE4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti303W → S in BAD94223 (Ref. 3) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022216 Genomic DNA Translation: BAB02728.1
CP002686 Genomic DNA Translation: AEE75928.1
AK220861 mRNA Translation: BAD94223.1
AK228860 mRNA Translation: BAF00754.1
RefSeqiNP_188351.2, NM_112603.3
UniGeneiAt.38757

Genome annotation databases

EnsemblPlantsiAT3G17250.1; AT3G17250.1; AT3G17250
GeneIDi820986
GrameneiAT3G17250.1; AT3G17250.1; AT3G17250
KEGGiath:AT3G17250

Similar proteinsi

Entry informationi

Entry nameiP2C43_ARATH
AccessioniPrimary (citable) accession number: Q9LUU7
Secondary accession number(s): Q56ZV0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health