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Protein

Probable protein phosphatase 2C 43

Gene

At3g17250

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi163Manganese 1By similarity1
Metal bindingi163Manganese 2By similarity1
Metal bindingi164Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi341Manganese 2By similarity1
Metal bindingi384Manganese 2By similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

ReactomeiR-ATH-70895. Branched-chain amino acid catabolism.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 43 (EC:3.1.3.16)
Short name:
AtPP2C43
Gene namesi
Ordered Locus Names:At3g17250
ORF Names:MGD8.13, MGD8.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G17250.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679671 – 422Probable protein phosphatase 2C 43Add BLAST422

Proteomic databases

PaxDbiQ9LUU7.

Expressioni

Gene expression databases

GenevisibleiQ9LUU7. AT.

Interactioni

Protein-protein interaction databases

BioGridi6319. 1 interactor.
IntActiQ9LUU7. 1 interactor.
MINTiMINT-8390632.
STRINGi3702.AT3G17250.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LUU7.
SMRiQ9LUU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini117 – 393PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST277

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000233896.
InParanoidiQ9LUU7.
KOiK14803.
OMAiRIHDSIC.
OrthoDBiEOG09360E05.
PhylomeDBiQ9LUU7.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LUU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTSKASVTQ TWLLYTQLCL WKDLIIRYVR QIIRRAKSML FSQNMVADSA
60 70 80 90 100
EISVIDVKSH LSVAKDPSNF QIAEIRIHDS ICIDIPSSEE TPLLESIKSC
110 120 130 140 150
SATTIEEHVT EFVPNISSGS YADKGDYREY MEDEHICIDD LSDHLGSSFY
160 170 180 190 200
RFPVPMAFYG VFDGHGGSDA SQYIKENAMS LFFEDAVFRQ SPSVVDSLFL
210 220 230 240 250
KELETSHREA YRLADLAMED ERIVSSSCGT TALTALVIGR HLMVANVGDC
260 270 280 290 300
RAVLCRKGKA VDMSFDHKST FEPERRRVED LGGYFEGEYL YGDLAVTRAL
310 320 330 340 350
GDWSIKRFSP LGESLSPLIS DPDIQQMILT EEDEFLIMGC DGVWDVMTSQ
360 370 380 390 400
YAVTFVRQGL RRHGDPRRCA MELGREALRL DSSDNVTVVV ICFSSSPAPQ
410 420
RRRIRFCVSD EARARLQTML EG
Length:422
Mass (Da):47,599
Last modified:October 1, 2000 - v1
Checksum:i63B7B3E7DD69FCE4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti303W → S in BAD94223 (Ref. 3) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022216 Genomic DNA. Translation: BAB02728.1.
CP002686 Genomic DNA. Translation: AEE75928.1.
AK220861 mRNA. Translation: BAD94223.1.
AK228860 mRNA. Translation: BAF00754.1.
RefSeqiNP_188351.2. NM_112603.3.
UniGeneiAt.38757.

Genome annotation databases

EnsemblPlantsiAT3G17250.1; AT3G17250.1; AT3G17250.
GeneIDi820986.
GrameneiAT3G17250.1; AT3G17250.1; AT3G17250.
KEGGiath:AT3G17250.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022216 Genomic DNA. Translation: BAB02728.1.
CP002686 Genomic DNA. Translation: AEE75928.1.
AK220861 mRNA. Translation: BAD94223.1.
AK228860 mRNA. Translation: BAF00754.1.
RefSeqiNP_188351.2. NM_112603.3.
UniGeneiAt.38757.

3D structure databases

ProteinModelPortaliQ9LUU7.
SMRiQ9LUU7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi6319. 1 interactor.
IntActiQ9LUU7. 1 interactor.
MINTiMINT-8390632.
STRINGi3702.AT3G17250.1.

Proteomic databases

PaxDbiQ9LUU7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G17250.1; AT3G17250.1; AT3G17250.
GeneIDi820986.
GrameneiAT3G17250.1; AT3G17250.1; AT3G17250.
KEGGiath:AT3G17250.

Organism-specific databases

TAIRiAT3G17250.

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000233896.
InParanoidiQ9LUU7.
KOiK14803.
OMAiRIHDSIC.
OrthoDBiEOG09360E05.
PhylomeDBiQ9LUU7.

Enzyme and pathway databases

ReactomeiR-ATH-70895. Branched-chain amino acid catabolism.

Miscellaneous databases

PROiQ9LUU7.

Gene expression databases

GenevisibleiQ9LUU7. AT.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP2C43_ARATH
AccessioniPrimary (citable) accession number: Q9LUU7
Secondary accession number(s): Q56ZV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.