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Q9LUU7

- P2C43_ARATH

UniProt

Q9LUU7 - P2C43_ARATH

Protein

Probable protein phosphatase 2C 43

Gene

At3g17250

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi163 – 1631Manganese 1By similarity
    Metal bindingi163 – 1631Manganese 2By similarity
    Metal bindingi164 – 1641Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi341 – 3411Manganese 2By similarity
    Metal bindingi384 – 3841Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT3G17250-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 43 (EC:3.1.3.16)
    Short name:
    AtPP2C43
    Gene namesi
    Ordered Locus Names:At3g17250
    ORF Names:MGD8.13, MGD8.8
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G17250.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 422422Probable protein phosphatase 2C 43PRO_0000367967Add
    BLAST

    Proteomic databases

    PaxDbiQ9LUU7.
    PRIDEiQ9LUU7.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9LUU7.

    Interactioni

    Protein-protein interaction databases

    BioGridi6319. 1 interaction.
    IntActiQ9LUU7. 1 interaction.
    MINTiMINT-8390632.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9LUU7.
    SMRiQ9LUU7. Positions 116-393.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini117 – 386270PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233896.
    InParanoidiQ9LUU7.
    KOiK14803.
    OMAiRHLMVAN.
    PhylomeDBiQ9LUU7.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9LUU7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRTSKASVTQ TWLLYTQLCL WKDLIIRYVR QIIRRAKSML FSQNMVADSA    50
    EISVIDVKSH LSVAKDPSNF QIAEIRIHDS ICIDIPSSEE TPLLESIKSC 100
    SATTIEEHVT EFVPNISSGS YADKGDYREY MEDEHICIDD LSDHLGSSFY 150
    RFPVPMAFYG VFDGHGGSDA SQYIKENAMS LFFEDAVFRQ SPSVVDSLFL 200
    KELETSHREA YRLADLAMED ERIVSSSCGT TALTALVIGR HLMVANVGDC 250
    RAVLCRKGKA VDMSFDHKST FEPERRRVED LGGYFEGEYL YGDLAVTRAL 300
    GDWSIKRFSP LGESLSPLIS DPDIQQMILT EEDEFLIMGC DGVWDVMTSQ 350
    YAVTFVRQGL RRHGDPRRCA MELGREALRL DSSDNVTVVV ICFSSSPAPQ 400
    RRRIRFCVSD EARARLQTML EG 422
    Length:422
    Mass (Da):47,599
    Last modified:October 1, 2000 - v1
    Checksum:i63B7B3E7DD69FCE4
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti303 – 3031W → S in BAD94223. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB022216 Genomic DNA. Translation: BAB02728.1.
    CP002686 Genomic DNA. Translation: AEE75928.1.
    AK220861 mRNA. Translation: BAD94223.1.
    AK228860 mRNA. Translation: BAF00754.1.
    RefSeqiNP_188351.2. NM_112603.2.
    UniGeneiAt.38757.

    Genome annotation databases

    EnsemblPlantsiAT3G17250.1; AT3G17250.1; AT3G17250.
    GeneIDi820986.
    KEGGiath:AT3G17250.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB022216 Genomic DNA. Translation: BAB02728.1 .
    CP002686 Genomic DNA. Translation: AEE75928.1 .
    AK220861 mRNA. Translation: BAD94223.1 .
    AK228860 mRNA. Translation: BAF00754.1 .
    RefSeqi NP_188351.2. NM_112603.2.
    UniGenei At.38757.

    3D structure databases

    ProteinModelPortali Q9LUU7.
    SMRi Q9LUU7. Positions 116-393.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 6319. 1 interaction.
    IntActi Q9LUU7. 1 interaction.
    MINTi MINT-8390632.

    Proteomic databases

    PaxDbi Q9LUU7.
    PRIDEi Q9LUU7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G17250.1 ; AT3G17250.1 ; AT3G17250 .
    GeneIDi 820986.
    KEGGi ath:AT3G17250.

    Organism-specific databases

    TAIRi AT3G17250.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233896.
    InParanoidi Q9LUU7.
    KOi K14803.
    OMAi RHLMVAN.
    PhylomeDBi Q9LUU7.

    Enzyme and pathway databases

    BioCyci ARA:AT3G17250-MONOMER.

    Gene expression databases

    Genevestigatori Q9LUU7.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
      Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
      DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
      Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
      , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
      Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C43_ARATH
    AccessioniPrimary (citable) accession number: Q9LUU7
    Secondary accession number(s): Q56ZV0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3