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Protein

Probable protein phosphatase 2C 40

Gene

At3g16560

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi180Manganese 1By similarity1
Metal bindingi180Manganese 2By similarity1
Metal bindingi181Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi408Manganese 2By similarity1
Metal bindingi471Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 40 (EC:3.1.3.16)
Short name:
AtPP2C40
Alternative name(s):
Protein phosphatase 2C homolog 1
Gene namesi
Ordered Locus Names:At3g16560
ORF Names:MDC8.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G16560
TAIRilocus:2089293 AT3G16560

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003012571 – 493Probable protein phosphatase 2C 40Add BLAST493

Proteomic databases

PaxDbiQ9LUS8
PRIDEiQ9LUS8

PTM databases

iPTMnetiQ9LUS8

Expressioni

Gene expression databases

ExpressionAtlasiQ9LUS8 baseline and differential
GenevisibleiQ9LUS8 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G16560.1

Structurei

3D structure databases

ProteinModelPortaliQ9LUS8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini145 – 480PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST336

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi80 – 139Ser-richAdd BLAST60
Compositional biasi465 – 468Poly-Arg4

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0700 Eukaryota
COG0631 LUCA
HOGENOMiHOG000240776
InParanoidiQ9LUS8
OMAiGYQCNNK
OrthoDBiEOG09360EX3
PhylomeDBiQ9LUS8

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 2 hits
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LUS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQEGTDPYGE IEISFGYQCN NKKIGIPEDK IADGREVLGG FRLQKTSSFS
60 70 80 90 100
CLSGAALSGN PTLANTNICN GVIGSEILPS LDSPKSFRKV PSSPALSKLD
110 120 130 140 150
ILSPSLHGSM VSLSCSSSTS PSPPEPESCY LTSMSSPSSV NEGFLLSAME
160 170 180 190 200
VQVAGGAAGE DRVQAVCSEE NGWLFCAIYD GFNGRDAADF LACTLYESIV
210 220 230 240 250
FHLQLLDRQM KQTKSDDDGE KLELLSNISN VDYSSTDLFR QGVLDCLNRA
260 270 280 290 300
LFQAETDFLR MVEQEMEERP DLVSVGSCVL VTLLVGKDLY VLNLGDSRAV
310 320 330 340 350
LATYNGNKKL QAVQLTEDHT VDNEVEEARL LSEHLDDPKI VIGGKIKGKL
360 370 380 390 400
KVTRALGVGY LKKEKLNDAL MGILRVRNLL SPPYVSVEPS MRVHKITESD
410 420 430 440 450
HFVIVASDGL FDFFSNEEAI GLVHSFVSSN PSGDPAKFLL ERLVAKAAAR
460 470 480 490
AGFTLEELTN VPAGRRRRYH DDVTIMVITL GTDQRTSKAS TFV
Length:493
Mass (Da):53,614
Last modified:October 1, 2000 - v1
Checksum:i613ED80B06B8C844
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti372G → E in AAM64473 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022217 Genomic DNA Translation: BAB02747.1
CP002686 Genomic DNA Translation: AEE75836.1
CP002686 Genomic DNA Translation: ANM63918.1
CP002686 Genomic DNA Translation: ANM63920.1
AY136458 mRNA Translation: AAM97123.1
BT008864 mRNA Translation: AAP68303.1
AY086406 mRNA Translation: AAM64473.1
RefSeqiNP_001325978.1, NM_001338238.1
NP_001325980.1, NM_001338240.1
NP_566554.1, NM_112529.3
UniGeneiAt.38878

Genome annotation databases

EnsemblPlantsiAT3G16560.1; AT3G16560.1; AT3G16560
AT3G16560.2; AT3G16560.2; AT3G16560
AT3G16560.4; AT3G16560.4; AT3G16560
GeneIDi820905
GrameneiAT3G16560.1; AT3G16560.1; AT3G16560
AT3G16560.2; AT3G16560.2; AT3G16560
AT3G16560.4; AT3G16560.4; AT3G16560
KEGGiath:AT3G16560

Similar proteinsi

Entry informationi

Entry nameiP2C40_ARATH
AccessioniPrimary (citable) accession number: Q9LUS8
Secondary accession number(s): Q8LCU0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health