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Q9LUS8

- P2C40_ARATH

UniProt

Q9LUS8 - P2C40_ARATH

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Protein

Probable protein phosphatase 2C 40

Gene

At3g16560

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi180 – 1801Manganese 1By similarity
Metal bindingi180 – 1801Manganese 2By similarity
Metal bindingi181 – 1811Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi408 – 4081Manganese 2By similarity
Metal bindingi471 – 4711Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT3G16560-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 40 (EC:3.1.3.16)
Short name:
AtPP2C40
Alternative name(s):
Protein phosphatase 2C homolog 1
Gene namesi
Ordered Locus Names:At3g16560
ORF Names:MDC8.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 3

Organism-specific databases

TAIRiAT3G16560.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 493493Probable protein phosphatase 2C 40PRO_0000301257Add
BLAST

Proteomic databases

PRIDEiQ9LUS8.

Expressioni

Gene expression databases

GenevestigatoriQ9LUS8.

Structurei

3D structure databases

ProteinModelPortaliQ9LUS8.
SMRiQ9LUS8. Positions 131-482.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini139 – 452314PP2C-likeAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi80 – 13960Ser-richAdd
BLAST
Compositional biasi465 – 4684Poly-Arg

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000240776.
InParanoidiQ9LUS8.
OMAiENPLEYQ.
PhylomeDBiQ9LUS8.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9LUS8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQEGTDPYGE IEISFGYQCN NKKIGIPEDK IADGREVLGG FRLQKTSSFS
60 70 80 90 100
CLSGAALSGN PTLANTNICN GVIGSEILPS LDSPKSFRKV PSSPALSKLD
110 120 130 140 150
ILSPSLHGSM VSLSCSSSTS PSPPEPESCY LTSMSSPSSV NEGFLLSAME
160 170 180 190 200
VQVAGGAAGE DRVQAVCSEE NGWLFCAIYD GFNGRDAADF LACTLYESIV
210 220 230 240 250
FHLQLLDRQM KQTKSDDDGE KLELLSNISN VDYSSTDLFR QGVLDCLNRA
260 270 280 290 300
LFQAETDFLR MVEQEMEERP DLVSVGSCVL VTLLVGKDLY VLNLGDSRAV
310 320 330 340 350
LATYNGNKKL QAVQLTEDHT VDNEVEEARL LSEHLDDPKI VIGGKIKGKL
360 370 380 390 400
KVTRALGVGY LKKEKLNDAL MGILRVRNLL SPPYVSVEPS MRVHKITESD
410 420 430 440 450
HFVIVASDGL FDFFSNEEAI GLVHSFVSSN PSGDPAKFLL ERLVAKAAAR
460 470 480 490
AGFTLEELTN VPAGRRRRYH DDVTIMVITL GTDQRTSKAS TFV
Length:493
Mass (Da):53,614
Last modified:October 1, 2000 - v1
Checksum:i613ED80B06B8C844
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti372 – 3721G → E in AAM64473. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022217 Genomic DNA. Translation: BAB02747.1.
CP002686 Genomic DNA. Translation: AEE75836.1.
AY136458 mRNA. Translation: AAM97123.1.
BT008864 mRNA. Translation: AAP68303.1.
AY086406 mRNA. Translation: AAM64473.1.
RefSeqiNP_566554.1. NM_112529.2.
UniGeneiAt.38878.

Genome annotation databases

EnsemblPlantsiAT3G16560.1; AT3G16560.1; AT3G16560.
GeneIDi820905.
KEGGiath:AT3G16560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022217 Genomic DNA. Translation: BAB02747.1 .
CP002686 Genomic DNA. Translation: AEE75836.1 .
AY136458 mRNA. Translation: AAM97123.1 .
BT008864 mRNA. Translation: AAP68303.1 .
AY086406 mRNA. Translation: AAM64473.1 .
RefSeqi NP_566554.1. NM_112529.2.
UniGenei At.38878.

3D structure databases

ProteinModelPortali Q9LUS8.
SMRi Q9LUS8. Positions 131-482.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q9LUS8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT3G16560.1 ; AT3G16560.1 ; AT3G16560 .
GeneIDi 820905.
KEGGi ath:AT3G16560.

Organism-specific databases

TAIRi AT3G16560.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000240776.
InParanoidi Q9LUS8.
OMAi ENPLEYQ.
PhylomeDBi Q9LUS8.

Enzyme and pathway databases

BioCyci ARA:AT3G16560-MONOMER.

Miscellaneous databases

PROi Q9LUS8.

Gene expression databases

Genevestigatori Q9LUS8.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 2 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
    Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
    DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C40_ARATH
AccessioniPrimary (citable) accession number: Q9LUS8
Secondary accession number(s): Q8LCU0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 1, 2000
Last modified: November 26, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3