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Q9LUS8 (P2C40_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 40

Short name=AtPP2C40
EC=3.1.3.16
Alternative name(s):
Protein phosphatase 2C homolog 1
Gene names
Ordered Locus Names:At3g16560
ORF Names:MDC8.3
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length493 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 493493Probable protein phosphatase 2C 40
PRO_0000301257

Regions

Domain139 – 452314PP2C-like
Compositional bias80 – 13960Ser-rich
Compositional bias465 – 4684Poly-Arg

Sites

Metal binding1801Manganese 1 By similarity
Metal binding1801Manganese 2 By similarity
Metal binding1811Manganese 1; via carbonyl oxygen By similarity
Metal binding4081Manganese 2 By similarity
Metal binding4711Manganese 2 By similarity

Experimental info

Sequence conflict3721G → E in AAM64473. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q9LUS8 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 613ED80B06B8C844

FASTA49353,614
        10         20         30         40         50         60 
MQEGTDPYGE IEISFGYQCN NKKIGIPEDK IADGREVLGG FRLQKTSSFS CLSGAALSGN 

        70         80         90        100        110        120 
PTLANTNICN GVIGSEILPS LDSPKSFRKV PSSPALSKLD ILSPSLHGSM VSLSCSSSTS 

       130        140        150        160        170        180 
PSPPEPESCY LTSMSSPSSV NEGFLLSAME VQVAGGAAGE DRVQAVCSEE NGWLFCAIYD 

       190        200        210        220        230        240 
GFNGRDAADF LACTLYESIV FHLQLLDRQM KQTKSDDDGE KLELLSNISN VDYSSTDLFR 

       250        260        270        280        290        300 
QGVLDCLNRA LFQAETDFLR MVEQEMEERP DLVSVGSCVL VTLLVGKDLY VLNLGDSRAV 

       310        320        330        340        350        360 
LATYNGNKKL QAVQLTEDHT VDNEVEEARL LSEHLDDPKI VIGGKIKGKL KVTRALGVGY 

       370        380        390        400        410        420 
LKKEKLNDAL MGILRVRNLL SPPYVSVEPS MRVHKITESD HFVIVASDGL FDFFSNEEAI 

       430        440        450        460        470        480 
GLVHSFVSSN PSGDPAKFLL ERLVAKAAAR AGFTLEELTN VPAGRRRRYH DDVTIMVITL 

       490 
GTDQRTSKAS TFV 

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB022217 Genomic DNA. Translation: BAB02747.1.
CP002686 Genomic DNA. Translation: AEE75836.1.
AY136458 mRNA. Translation: AAM97123.1.
BT008864 mRNA. Translation: AAP68303.1.
AY086406 mRNA. Translation: AAM64473.1.
RefSeqNP_566554.1. NM_112529.2.
UniGeneAt.38878.

3D structure databases

ProteinModelPortalQ9LUS8.
SMRQ9LUS8. Positions 131-482.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ9LUS8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G16560.1; AT3G16560.1; AT3G16560.
GeneID820905.
KEGGath:AT3G16560.

Organism-specific databases

TAIRAT3G16560.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000240776.
InParanoidQ9LUS8.
OMAENPLEYQ.
PhylomeDBQ9LUS8.
ProtClustDBCLSN2688452.

Enzyme and pathway databases

BioCycARA:AT3G16560-MONOMER.

Gene expression databases

GenevestigatorQ9LUS8.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 2 hits.
ProtoNetSearch...

Other

PROQ9LUS8.

Entry information

Entry nameP2C40_ARATH
AccessionPrimary (citable) accession number: Q9LUS8
Secondary accession number(s): Q8LCU0
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names