Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9LUI3

- TSO1_ARATH

UniProt

Q9LUI3 - TSO1_ARATH

Protein

CRC domain-containing protein TSO1

Gene

TSO1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Probable floral-specific cell division component, required for proper organ formation in flowers. Regulates the floral meristem cell division and the inflorescence meristem organization. Plays a role in development of both male and female reproductive tissues.4 Publications

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. sequence-specific DNA binding transcription factor activity Source: TAIR

    GO - Biological processi

    1. floral organ morphogenesis Source: UniProtKB
    2. regulation of cell division Source: UniProtKB
    3. regulation of meristem structural organization Source: TAIR

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    CRC domain-containing protein TSO1
    Gene namesi
    Name:TSO1
    Ordered Locus Names:At3g22780
    ORF Names:MWI23.15
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G22780.

    Subcellular locationi

    Nucleus 2 Publications

    GO - Cellular componenti

    1. nucleus Source: UniProtKB

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Disruption phenotypei

    Despite a wild-type flower phenotype, the null mutant presents defects in pollen, carpel and ovule development, including a failure in megasporogenesis. Small siliques.3 Publications

    Mutagenesis

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Mutagenesisi403 – 4031C → Y: Abnormalities in floral meristems and sepals including increased cell size, decreased cell number, disorganized layer structure, increased DNA content per cell, and partially formed cell walls. Resulting phenotype is callus-like tissues in place of floral organs. 1 Publication
    Mutagenesisi501 – 5011C → Y: Abnormalities in floral meristems and sepals including increased cell size, decreased cell number, disorganized layer structure, increased DNA content per cell, and partially formed cell walls. Resulting phenotype is callus-like tissues in place of floral organs. 1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 695695CRC domain-containing protein TSO1PRO_0000418166Add
    BLAST

    Proteomic databases

    PRIDEiQ9LUI3.

    Expressioni

    Tissue specificityi

    Ubiquitous but expressed mostly in flowers with highest levels in developing ovules and microspores.3 Publications

    Developmental stagei

    Expressed at the first stage of pollen development in uninucleate microspores and bicellular pollen but not in tricellular and mature pollen.1 Publication

    Gene expression databases

    GenevestigatoriQ9LUI3.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT3G22780.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9LUI3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini399 – 524126CRCPROSITE-ProRule annotationAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi269 – 28315Nuclear localization signalSequence AnalysisAdd
    BLAST

    Domaini

    The cysteine-rich domain CRC binds zinc in vitro.

    Sequence similaritiesi

    Belongs to the lin-54 family.Curated
    Contains 1 CRC domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG258818.
    HOGENOMiHOG000084455.
    InParanoidiQ9LUI3.
    OMAiLVIMESK.
    PhylomeDBiQ9LUI3.

    Family and domain databases

    InterProiIPR005172. CRC.
    IPR028307. Lin-54_fam.
    [Graphical view]
    PANTHERiPTHR12446. PTHR12446. 1 hit.
    PfamiPF03638. TCR. 2 hits.
    [Graphical view]
    PROSITEiPS51634. CRC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9LUI3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDKSQKNPTS QIGTSTPKSK FEDSPVFNYI SNLSPIESVK SISTAQTFSS    50
    LSFTSPPPVF TSPHVISHRE SRFFRCHNSV DRSKHLESLD GSAVKGEVVV 100
    PLVEDLNKEA SLEDEEETSV ETSSELPQIM KFDSQTSEHS DSPCTEDVVI 150
    EASSDPPRGD NGSSSEDVTM GLQNMLVVRE GNDTPGCGRL ISDATELLVF 200
    RSPNDSEAFR CLVDKISSSE RRFCAGVKST KRPDINKDIP ANGSSNENQP 250
    LAVLPTNESV FNLHRGGMRR RCLDFEMPGK RKKDIVDDQQ SVCDNNVAGE 300
    SSSSCVVPGI GLHLNAVAMS AKDSNISVIH GYSISGEIQK SFSGSTTPIQ 350
    SQDTVQETSD QAENEPVEEV PKALVFPELN LGSLKKKMRK SEQAGEGESC 400
    KRCNCKKSKC LKLYCECFAA GVYCIEPCSC IDCFNKPIHE ETVLATRKQI 450
    ESRNPLAFAP KVIRNADSIM EASDDASKTP ASARHKRGCN CKKSNCMKKY 500
    CECYQGGVGC SMNCRCEGCT NVFGRKDGSL LVIMESKLEE NQETYEKRIA 550
    KIQHNVEVSK EVEQNPSSDQ PSTPLPPYRH LVVHQPFLSK NRLPPTQFFL 600
    GTGSSSFRKP NSDLAQSQNE KKPLETVTED KTEIMPEILL NSPIANIKAI 650
    SPNSKRVSPP QPGSSESGSI LRRRGNGRKL ILRSIPAFPS LNPNQ 695
    Length:695
    Mass (Da):76,277
    Last modified:October 1, 2000 - v1
    Checksum:i34BBA0E450F6BCE1
    GO

    Sequence cautioni

    The sequence AAK76693.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti130 – 1301M → L in AAF27433. (PubMed:10769244)Curated
    Sequence conflicti130 – 1301M → L in AAF69124. (PubMed:10769245)Curated
    Sequence conflicti375 – 3751V → M in AAK76693. (PubMed:14593172)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF206324 mRNA. Translation: AAF27433.1.
    AF204059 mRNA. Translation: AAF69124.1.
    AB022223 Genomic DNA. Translation: BAB01253.1.
    CP002686 Genomic DNA. Translation: AEE76676.1.
    AY046019 mRNA. Translation: AAK76693.1. Different initiation.
    AY142642 mRNA. Translation: AAN13100.1.
    RefSeqiNP_566718.2. NM_113177.3.
    UniGeneiAt.24953.
    At.68193.

    Genome annotation databases

    EnsemblPlantsiAT3G22780.1; AT3G22780.1; AT3G22780.
    GeneIDi821849.
    KEGGiath:AT3G22780.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF206324 mRNA. Translation: AAF27433.1 .
    AF204059 mRNA. Translation: AAF69124.1 .
    AB022223 Genomic DNA. Translation: BAB01253.1 .
    CP002686 Genomic DNA. Translation: AEE76676.1 .
    AY046019 mRNA. Translation: AAK76693.1 . Different initiation.
    AY142642 mRNA. Translation: AAN13100.1 .
    RefSeqi NP_566718.2. NM_113177.3.
    UniGenei At.24953.
    At.68193.

    3D structure databases

    ProteinModelPortali Q9LUI3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT3G22780.1-P.

    Proteomic databases

    PRIDEi Q9LUI3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G22780.1 ; AT3G22780.1 ; AT3G22780 .
    GeneIDi 821849.
    KEGGi ath:AT3G22780.

    Organism-specific databases

    TAIRi AT3G22780.

    Phylogenomic databases

    eggNOGi NOG258818.
    HOGENOMi HOG000084455.
    InParanoidi Q9LUI3.
    OMAi LVIMESK.
    PhylomeDBi Q9LUI3.

    Gene expression databases

    Genevestigatori Q9LUI3.

    Family and domain databases

    InterProi IPR005172. CRC.
    IPR028307. Lin-54_fam.
    [Graphical view ]
    PANTHERi PTHR12446. PTHR12446. 1 hit.
    Pfami PF03638. TCR. 2 hits.
    [Graphical view ]
    PROSITEi PS51634. CRC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Regulation of meristem organization and cell division by TSO1, an Arabidopsis gene with cysteine-rich repeats."
      Song J.Y., Leung T., Ehler L.K., Wang C., Liu Z.
      Development 127:2207-2217(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, MUTAGENESIS OF CYS-403, SUBCELLULAR LOCATION.
      Strain: cv. Landsberg erecta.
      Tissue: Flower.
    2. "TSO1 is a novel protein that modulates cytokinesis and cell expansion in Arabidopsis."
      Hauser B.A., He J.Q., Park S.O., Gasser C.S.
      Development 127:2219-2226(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, MUTAGENESIS OF CYS-501, SUBCELLULAR LOCATION.
      Strain: cv. Landsberg erecta.
    3. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
      Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
      DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    4. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    5. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 160-695.
      Strain: cv. Columbia.
    6. "TSO1 functions in cell division during Arabidopsis flower development."
      Liu Z., Running M.P., Meyerowitz E.M.
      Development 124:665-672(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    7. "Arabidopsis TSO1 regulates directional processes in cells during floral organogenesis."
      Hauser B.A., Villanueva J.M., Gasser C.S.
      Genetics 150:411-423(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE.
    8. "The conserved cysteine-rich domain of a tesmin/TSO1-like protein binds zinc in vitro and TSO1 is required for both male and female fertility in Arabidopsis thaliana."
      Andersen S.U., Algreen-Petersen R.G., Hoedl M., Jurkiewicz A., Cvitanich C., Braunschweig U., Schauser L., Oh S.A., Twell D., Jensen E.O.
      J. Exp. Bot. 58:3657-3670(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE, ZINC-BINDING, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
    9. "Recessive antimorphic alleles overcome functionally redundant loci to reveal TSO1 function in Arabidopsis flowers and meristems."
      Sijacic P., Wang W., Liu Z.
      PLoS Genet. 7:E1002352-E1002352(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: DISRUPTION PHENOTYPE.

    Entry informationi

    Entry nameiTSO1_ARATH
    AccessioniPrimary (citable) accession number: Q9LUI3
    Secondary accession number(s): Q8H1Q0, Q94AI2, Q9LE32
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 11, 2012
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3