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Protein

CRC domain-containing protein TSO1

Gene

TSO1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable floral-specific cell division component, required for proper organ formation in flowers. Regulates the floral meristem cell division and the inflorescence meristem organization. Plays a role in development of both male and female reproductive tissues.4 Publications

GO - Molecular functioni

  • DNA binding transcription factor activity Source: TAIR
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

  • floral organ morphogenesis Source: UniProtKB
  • regulation of cell division Source: UniProtKB
  • regulation of meristem structural organization Source: TAIR

Keywordsi

Molecular functionDevelopmental protein
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
CRC domain-containing protein TSO1
Gene namesi
Name:TSO1
Ordered Locus Names:At3g22780
ORF Names:MWI23.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G22780
TAIRilocus:2094369 AT3G22780

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Despite a wild-type flower phenotype, the null mutant presents defects in pollen, carpel and ovule development, including a failure in megasporogenesis. Small siliques.3 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi403C → Y: Abnormalities in floral meristems and sepals including increased cell size, decreased cell number, disorganized layer structure, increased DNA content per cell, and partially formed cell walls. Resulting phenotype is callus-like tissues in place of floral organs. 1 Publication1
Mutagenesisi501C → Y: Abnormalities in floral meristems and sepals including increased cell size, decreased cell number, disorganized layer structure, increased DNA content per cell, and partially formed cell walls. Resulting phenotype is callus-like tissues in place of floral organs. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004181661 – 695CRC domain-containing protein TSO1Add BLAST695

Proteomic databases

PaxDbiQ9LUI3
PRIDEiQ9LUI3

PTM databases

iPTMnetiQ9LUI3

Expressioni

Tissue specificityi

Ubiquitous but expressed mostly in flowers with highest levels in developing ovules and microspores.3 Publications

Developmental stagei

Expressed at the first stage of pollen development in uninucleate microspores and bicellular pollen but not in tricellular and mature pollen.1 Publication

Gene expression databases

ExpressionAtlasiQ9LUI3 baseline and differential
GenevisibleiQ9LUI3 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G22780.1

Structurei

3D structure databases

ProteinModelPortaliQ9LUI3
SMRiQ9LUI3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini399 – 524CRCPROSITE-ProRule annotationAdd BLAST126

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi269 – 283Nuclear localization signalSequence analysisAdd BLAST15

Domaini

The cysteine-rich domain CRC binds zinc in vitro.

Sequence similaritiesi

Belongs to the lin-54 family.Curated

Phylogenomic databases

eggNOGiKOG1171 Eukaryota
ENOG4110UR5 LUCA
HOGENOMiHOG000084455
InParanoidiQ9LUI3
OMAiEAFRCLV
OrthoDBiEOG093602OU
PhylomeDBiQ9LUI3

Family and domain databases

InterProiView protein in InterPro
IPR005172 CRC
IPR028307 Lin-54_fam
IPR033467 Tesmin/TSO1-like_CXC
PANTHERiPTHR12446 PTHR12446, 2 hits
PfamiView protein in Pfam
PF03638 TCR, 2 hits
SMARTiView protein in SMART
SM01114 CXC, 2 hits
PROSITEiView protein in PROSITE
PS51634 CRC, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LUI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKSQKNPTS QIGTSTPKSK FEDSPVFNYI SNLSPIESVK SISTAQTFSS
60 70 80 90 100
LSFTSPPPVF TSPHVISHRE SRFFRCHNSV DRSKHLESLD GSAVKGEVVV
110 120 130 140 150
PLVEDLNKEA SLEDEEETSV ETSSELPQIM KFDSQTSEHS DSPCTEDVVI
160 170 180 190 200
EASSDPPRGD NGSSSEDVTM GLQNMLVVRE GNDTPGCGRL ISDATELLVF
210 220 230 240 250
RSPNDSEAFR CLVDKISSSE RRFCAGVKST KRPDINKDIP ANGSSNENQP
260 270 280 290 300
LAVLPTNESV FNLHRGGMRR RCLDFEMPGK RKKDIVDDQQ SVCDNNVAGE
310 320 330 340 350
SSSSCVVPGI GLHLNAVAMS AKDSNISVIH GYSISGEIQK SFSGSTTPIQ
360 370 380 390 400
SQDTVQETSD QAENEPVEEV PKALVFPELN LGSLKKKMRK SEQAGEGESC
410 420 430 440 450
KRCNCKKSKC LKLYCECFAA GVYCIEPCSC IDCFNKPIHE ETVLATRKQI
460 470 480 490 500
ESRNPLAFAP KVIRNADSIM EASDDASKTP ASARHKRGCN CKKSNCMKKY
510 520 530 540 550
CECYQGGVGC SMNCRCEGCT NVFGRKDGSL LVIMESKLEE NQETYEKRIA
560 570 580 590 600
KIQHNVEVSK EVEQNPSSDQ PSTPLPPYRH LVVHQPFLSK NRLPPTQFFL
610 620 630 640 650
GTGSSSFRKP NSDLAQSQNE KKPLETVTED KTEIMPEILL NSPIANIKAI
660 670 680 690
SPNSKRVSPP QPGSSESGSI LRRRGNGRKL ILRSIPAFPS LNPNQ
Length:695
Mass (Da):76,277
Last modified:October 1, 2000 - v1
Checksum:i34BBA0E450F6BCE1
GO

Sequence cautioni

The sequence AAK76693 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti130M → L in AAF27433 (PubMed:10769244).Curated1
Sequence conflicti130M → L in AAF69124 (PubMed:10769245).Curated1
Sequence conflicti375V → M in AAK76693 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF206324 mRNA Translation: AAF27433.1
AF204059 mRNA Translation: AAF69124.1
AB022223 Genomic DNA Translation: BAB01253.1
CP002686 Genomic DNA Translation: AEE76676.1
AY046019 mRNA Translation: AAK76693.1 Different initiation.
AY142642 mRNA Translation: AAN13100.1
RefSeqiNP_566718.2, NM_113177.4
UniGeneiAt.24953
At.68193

Genome annotation databases

EnsemblPlantsiAT3G22780.1; AT3G22780.1; AT3G22780
GeneIDi821849
GrameneiAT3G22780.1; AT3G22780.1; AT3G22780
KEGGiath:AT3G22780

Similar proteinsi

Entry informationi

Entry nameiTSO1_ARATH
AccessioniPrimary (citable) accession number: Q9LUI3
Secondary accession number(s): Q8H1Q0, Q94AI2, Q9LE32
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2012
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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