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Protein

Heat stress transcription factor A-6b

Gene

HSFA6b

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi59 – 153By similarityAdd BLAST95

GO - Molecular functioni

  • DNA binding transcription factor activity Source: TAIR
  • sequence-specific DNA binding Source: InterPro

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processStress response, Transcription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-ATH-3371453 Regulation of HSF1-mediated heat shock response
R-ATH-3371511 HSF1 activation
R-ATH-3371568 Attenuation phase
R-ATH-3371571 HSF1-dependent transactivation

Names & Taxonomyi

Protein namesi
Recommended name:
Heat stress transcription factor A-6b
Short name:
AtHsfA6b
Alternative name(s):
AtHsf-07
Gene namesi
Name:HSFA6b
Synonyms:HSF07
Ordered Locus Names:At3g22830
ORF Names:MWI23.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G22830
TAIRilocus:2094339 AT3G22830

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002708081 – 406Heat stress transcription factor A-6bAdd BLAST406

Post-translational modificationi

Exhibits temperature-dependent phosphorylation.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9LUH8

Expressioni

Gene expression databases

ExpressionAtlasiQ9LUH8 baseline and differential
GenevisibleiQ9LUH8 AT

Interactioni

Subunit structurei

Homotrimer.By similarity

Protein-protein interaction databases

STRINGi3702.AT3G22830.1

Structurei

3D structure databases

ProteinModelPortaliQ9LUH8
SMRiQ9LUH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni174 – 240Hydrophobic repeat HR-A/BAdd BLAST67

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi253 – 269Bipartite nuclear localization signalSequence analysisAdd BLAST17
Motifi367 – 376AHA10
Motifi392 – 399Nuclear export signalSequence analysis8

Domaini

The hydrophobic-rich region (HR-A/B) corresponds to the oligomerization domain. AHA motif is a transcriptional activator element.1 Publication

Sequence similaritiesi

Belongs to the HSF family. Class A subfamily.Curated

Phylogenomic databases

eggNOGiKOG0627 Eukaryota
COG5169 LUCA
HOGENOMiHOG000237979
InParanoidiQ9LUH8
KOiK09419
OMAiRQNQANG
OrthoDBiEOG09360BUI
PhylomeDBiQ9LUH8

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000232 HSF_DNA-bd
IPR027725 HSF_fam
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR10015 PTHR10015, 1 hit
PfamiView protein in Pfam
PF00447 HSF_DNA-bind, 1 hit
PRINTSiPR00056 HSFDOMAIN
SMARTiView protein in SMART
SM00415 HSF, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00434 HSF_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LUH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPSFRFIKE EFPAGFSDSP SPPSSSSYLY SSSMAEAAIN DPTTLSYPQP
60 70 80 90 100
LEGLHESGPP PFLTKTYDLV EDSRTNHVVS WSKSNNSFIV WDPQAFSVTL
110 120 130 140 150
LPRFFKHNNF SSFVRQLNTY GFRKVNPDRW EFANEGFLRG QKHLLKNIRR
160 170 180 190 200
RKTSNNSNQM QQPQSSEQQS LDNFCIEVGR YGLDGEMDSL RRDKQVLMME
210 220 230 240 250
LVRLRQQQQS TKMYLTLIEE KLKKTESKQK QMMSFLARAM QNPDFIQQLV
260 270 280 290 300
EQKEKRKEIE EAISKKRQRP IDQGKRNVED YGDESGYGND VAASSSALIG
310 320 330 340 350
MSQEYTYGNM SEFEMSELDK LAMHIQGLGD NSSAREEVLN VEKGNDEEEV
360 370 380 390 400
EDQQQGYHKE NNEIYGEGFW EDLLNEGQNF DFEGDQENVD VLIQQLGYLG

SSSHTN
Length:406
Mass (Da):46,736
Last modified:October 1, 2000 - v1
Checksum:iF2DEE3A82536B698
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022223 Genomic DNA Translation: BAB01258.1
CP002686 Genomic DNA Translation: AEE76681.1
AY045974 mRNA Translation: AAK76648.1
AY079374 mRNA Translation: AAL85105.1
RefSeqiNP_188922.1, NM_113182.2
UniGeneiAt.6312
At.67265

Genome annotation databases

EnsemblPlantsiAT3G22830.1; AT3G22830.1; AT3G22830
GeneIDi821854
GrameneiAT3G22830.1; AT3G22830.1; AT3G22830
KEGGiath:AT3G22830

Similar proteinsi

Entry informationi

Entry nameiHFA6B_ARATH
AccessioniPrimary (citable) accession number: Q9LUH8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health