UniProtKB - Q9LUB7 (OBE2_ARATH)
(max 400 entries)x
Your basket is currently empty. i
Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)
Protein
Protein OBERON 2
Gene
OBE2
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Together with OBE1, required for the maintenance and/or establishment of both the shoot and root meristems, probably by controlling the expression of the meristem genes such as WUS, PLT1 and PLT2 and of genes required for auxin responses. Promotes cell meristematic activity via the WUSCHEL-CLAVATA pathway. Involved in the development of the basal pole and in auxin-mediated root and vascular development in the embryo. Confers sensitivity to turnip mosaic virus (TuMV) probably by promoting viral movement and multiplication via interaction with TuMV VPg.2 Publications
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 226 – 291 | PHD-typeAdd BLAST | 66 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- protein heterodimerization activity Source: UniProtKB
- protein homodimerization activity Source: UniProtKB
GO - Biological processi
- embryo development ending in seed dormancy Source: TAIR
- maintenance of root meristem identity Source: TAIR
- maintenance of shoot apical meristem identity Source: TAIR
- primary root development Source: TAIR
- regulation of gene expression Source: TAIR
- root meristem specification Source: TAIR
- transport of virus in host, cell to cell Source: UniProtKB
Keywordsi
Molecular function | Developmental protein |
Biological process | Host-virus interaction |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Protein OBERON 2Alternative name(s): Potyvirus VPg-interacting protein 1 |
Gene namesi | Name:OBE2 Synonyms:PVIP1 Ordered Locus Names:At5g48160 ORF Names:MIF21.5 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G48160. |
TAIRi | locus:2164713. AT5G48160. |
Pathology & Biotechi
Disruption phenotypei
No visible phenotype. When associated with OBE1 disruption, plants exhibit premature termination of the shoot meristem and impaired root apical meristem establishment, leading to a diminutive phenotype characterized by an absence of roots and defective development of the vasculature.2 Publications
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000399747 | 1 – 574 | Protein OBERON 2Add BLAST | 574 |
Proteomic databases
PaxDbi | Q9LUB7. |
PTM databases
iPTMneti | Q9LUB7. |
Expressioni
Tissue specificityi
Expressed in roots, seedlings, stems, leaves, flowers and siliques, especially in the vasculature.2 Publications
Developmental stagei
First observed in the embryo proper at the four-cell stage. Later expressed throughout the embryo from the eight-cell to the bent-cotyledon stages. Until the torpedo stage of development, mostly concentrated at the root pole. Hardly detected in the suspensor. Present in seedling roots. In mature and fully differentiated young roots, restricted to root tips.2 Publications
Inductioni
By auxin in the root elongation zone.1 Publication
Gene expression databases
ExpressionAtlasi | Q9LUB7. baseline and differential. |
Interactioni
Subunit structurei
Self-interacts. Interacts with OBE1, OBE3 and OBE4. Binds to VPg of pea seed borne mosaic virus (PSbMV), turnip mosaic virus (TuMV) and lettuce mosaic virus (LMV), but not with VPg of tobacco etch virus (TEV), cowpea mosaic virus (CPMV), tomato black ring virus (TBRV) and grapevine fan leaf virus (GFLV).2 Publications
GO - Molecular functioni
- protein heterodimerization activity Source: UniProtKB
- protein homodimerization activity Source: UniProtKB
Protein-protein interaction databases
BioGridi | 20115. 5 interactors. |
STRINGi | 3702.AT5G48160.1. |
Structurei
3D structure databases
ProteinModelPortali | Q9LUB7. |
SMRi | Q9LUB7. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 416 – 524 | Sequence analysisAdd BLAST | 109 |
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 226 – 291 | PHD-typeAdd BLAST | 66 |
Keywords - Domaini
Coiled coil, Zinc-fingerPhylogenomic databases
eggNOGi | ENOG410IGMY. Eukaryota. ENOG4110PA9. LUCA. |
HOGENOMi | HOG000029805. |
InParanoidi | Q9LUB7. |
OMAi | TWPAEPN. |
OrthoDBi | EOG093606AT. |
PhylomeDBi | Q9LUB7. |
Family and domain databases
InterProi | View protein in InterPro IPR004082. OBERON. IPR032535. Oberon_cc. IPR032881. Oberon_PHD. IPR001965. Znf_PHD. |
Pfami | View protein in Pfam PF16312. Oberon_cc. 1 hit. PF07227. PHD_Oberon. 1 hit. |
PIRSFi | PIRSF025218. DUF1423_pln. 1 hit. |
PRINTSi | PR01544. ARATH130DUF. |
SMARTi | View protein in SMART SM00249. PHD. 1 hit. |
PROSITEi | View protein in PROSITE PS01359. ZF_PHD_1. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q9LUB7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGTSSGSNHP HQMLPPRQQQ RSGGGLETAL SLVSSDQEPR RESPAESASS
60 70 80 90 100
QETWPLGDTV AGKKSMSQKT EPDSMEQTVN VMHHVSNADK VSVRDIARER
110 120 130 140 150
VELVAERMHR LPDEFLDELK NGLKSILEGN VAQSVDEFMF LQKVVQSRTD
160 170 180 190 200
LSSVTLVRAH RVQLEILVAI NTGIQAFLHP NISLSQPSLI EIFVYKRCRN
210 220 230 240 250
IACQNQLPAD DCYCDICTNR KGFCNLCMCT ICNKFDFSVN TCRWIGCDLC
260 270 280 290 300
SHWTHTDCAI RDGQITTGSS AKNNTSGPGE IVFKCRACNR TSELLGWVKD
310 320 330 340 350
VFQHCAPNWD RESLMKELDF VSRIFRGSED QRGRKLFWKC EELIDKIKGG
360 370 380 390 400
LAEATAAKLI LMFFQEIESD SAKSFENGEG GRLMAPQDAC NRIAEVVQET
410 420 430 440 450
LRKMEIVAEE KMRMFKKARM ALETCDRELE DKAKEVSELK AERQKKKLQI
460 470 480 490 500
DELERIVRLK QAEADMFQLK ANEAKREADR LQRIVLAKMD KSEEEYASNY
510 520 530 540 550
LKQRLSEAEA EKQYLFEKIK LQENSRVASQ SSGGGGDPSQ VMMYSKIRDL
560 570
LQGYNLSPKV DPQLNERNPF RSNP
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 136 | D → G in BAE99299 (Ref. 4) Curated | 1 | |
Sequence conflicti | 361 | L → F in BAH20018 (PubMed:19423640).Curated | 1 | |
Sequence conflicti | 493 | E → G in BAE99299 (Ref. 4) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB023039 Genomic DNA. Translation: BAA96996.1. CP002688 Genomic DNA. Translation: AED95626.1. CP002688 Genomic DNA. Translation: AED95627.1. AK317346 mRNA. Translation: BAH20018.1. AK317672 mRNA. Translation: BAH20332.1. AK220595 mRNA. Translation: BAD94916.1. AK227275 mRNA. Translation: BAE99299.1. |
RefSeqi | NP_001032031.1. NM_001036954.1. NP_199627.1. NM_124190.4. |
UniGenei | At.28240. |
Genome annotation databases
EnsemblPlantsi | AT5G48160.1; AT5G48160.1; AT5G48160. AT5G48160.2; AT5G48160.2; AT5G48160. |
GeneIDi | 834868. |
Gramenei | AT5G48160.1; AT5G48160.1; AT5G48160. AT5G48160.2; AT5G48160.2; AT5G48160. |
KEGGi | ath:AT5G48160. |
Similar proteinsi
Entry informationi
Entry namei | OBE2_ARATH | |
Accessioni | Q9LUB7Primary (citable) accession number: Q9LUB7 Secondary accession number(s): B9DH01, Q0WU99, Q570W2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 5, 2010 |
Last sequence update: | October 1, 2000 | |
Last modified: | December 20, 2017 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |