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Reviewed, UniProtKB/Swiss-Prot Q9LU91 (SKI14_ARATH)

Last modified June 16, 2009. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Web resources · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    F-box protein SKIP14
Alternative name(s):
    SKP1-interacting partner 14
Gene names
Name: SKIP14
Ordered Locus Names: At3g26000
ORF Names: MPE11.17
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidseurosids IIBrassicalesBrassicaceaeArabidopsis

Protein attributes

Sequence length453 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins By similarity.

Pathway

Protein modification; protein ubiquitination.

Subunit structure

Part of a SCF (ASK-cullin-F-box) protein ligase complex By similarity. Interacts with CUL1, SKP1A/ASK1 and SPK1B/ASK2.

Domain

The F-box is necessary for the interaction with ASK proteins By similarity.

Sequence similarities

Contains 1 F-box domain.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionprotein binding Ref.4

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

SKP1AQ392552EBI-604313,EBI-532357
SKP1BQ9FHW72EBI-604313,EBI-604076

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 453453F-box protein SKIP14
PRO_0000375237

Regions

Domain34 – 10471F-box; degenerate
Compositional bias368 – 44477Cys-rich

Experimental info

Sequence conflict4021K → E in AAM98151. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q9LU91-1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: CCD32A1DBA9039C4

FASTA45350,543
        10         20         30         40         50         60 
MALNFSHRPF SSHLSEEPMM IANGNWCSSF DNGRKNTGGD ASSVDILDVL PSDPFGMDIN 

        70         80         90        100        110        120 
NTFTAITGWL EDLEDDYNNQ YGRRRRDDIW IGDGNRQQLF AGLSFFWNNA MQFQSSGYSY 

       130        140        150        160        170        180 
GSESLFGGAF DGSLFSTCKF PESSGENNGF GGALDGDGSC HGAFISASSV DEVLSHENAR 

       190        200        210        220        230        240 
NGEVVGSSDR CNNGEEDAYV HPAIGFCLYH LRGKDLLSVS MVCKSLHTTV CDDTLLWKHI 

       250        260        270        280        290        300 
HICRPLNEKI TEEALLHLTE RAQGTMQCLR IVDCCRITDD CLKRVVARNR QVVKIGVPGC 

       310        320        330        340        350        360 
TRITIDGILS VLRDLKSAGK LQVKHLQLRG LFGVTKDHYD ELIDLLNIDN KVKQTIQKPR 

       370        380        390        400        410        420 
FYHRGEACVS CDDDRALDIE MCPKCQNFKL VYDCPAEDCK GKKKGSEECR ACSLCIQRCY 

       430        440        450 
HCGRCIIDTE YEEMFCLELL CAVCSKPTPK LTL 

« Hide

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
DNA Res. 7:131-135(2000) [PubMed: 10819329] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[3]"Arabidopsis ORF clones."
Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.
Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis."
Risseeuw E.P., Daskalchuk T.E., Banks T.W., Liu E., Cotelesage J., Hellmann H., Estelle M., Somers D.E., Crosby W.L.
Plant J. 34:753-767(2003) [PubMed: 12795696] [Abstract]
Cited for: INTERACTION WITH CUL1; SKP1A/ASK1 AND SPK1B/ASK2.

Web resources

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Cross-references

Sequence databases

AB023041 Genomic DNA. Translation: BAB01063.1.
AY058077 mRNA. Translation: AAL24185.1.
AY140009 mRNA. Translation: AAM98151.1.
BT015945 mRNA. Translation: AAV34775.1.
IPIIPI00529135.
RefSeqNP_566787.1.
UniGeneAt.23470

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActQ9LU91. 7 interactions.

Proteomic databases

PRIDEQ9LU91.

Genome annotation databases

GeneID822197.
KEGGath:AT3G26000.
NMPDRfig|3702.1.peg.14863.

Organism-specific databases

TAIRAt3g26000.

Phylogenomic databases

OMAQ9LU91. SAVRNEP.

Family and domain databases

PROSITEPS50181. FBOX. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSKI14_ARATH
AccessionPrimary (citable) accession number: Q9LU91
Secondary accession number(s): Q8L720
Entry history
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: October 1, 2000
Last modified: June 16, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Web resources · Cross-references · Entry information · Relevant documents