Probable cation-transporting ATPase - Arabidopsis thaliana (Mouse-ear cress)

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Q9LT02 (ATY1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 86. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Probable cation-transporting ATPase
EC=3.6.3.-

Gene names

Ordered Locus Names:	At5g23630
ORF Names:	MQM1.11

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	1179 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Involved in transport of cations Potential.
Catalytic activity	ATP + H₂O = ADP + phosphate.
Subcellular location	Membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. [View classification]
Sequence caution	The sequence BX831910 differs from that shown. Reason: Frameshift at position 1100.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Magnesium Metal-binding Nucleotide-binding
Molecular function	Hydrolase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular metal ion homeostasis Inferred from mutant phenotype. Source: TAIR cellular response to phosphate starvation Inferred from mutant phenotype. Source: TAIR meristem maintenance Inferred from mutant phenotype. Source: TAIR pollen germination Inferred from mutant phenotype. Source: TAIR pollen maturation Inferred from mutant phenotype. Source: TAIR stem cell fate determination Inferred from mutant phenotype. Source: TAIR
Cellular component	endoplasmic reticulum Inferred from direct assay. Source: TAIR integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from direct assay. Source: TAIR
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism Inferred from electronic annotation. Source: InterPro cation-transporting ATPase activity Inferred from genetic interaction. Source: TAIR metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 1179

1179

Probable cation-transporting ATPase

PRO_0000046420

Regions

Topological domain

1 – 20

Cytoplasmic Potential

Transmembrane

21 – 42

Helical; Potential

Topological domain

43 – 50

Extracellular Potential

Transmembrane

51 – 71

Helical; Potential

Topological domain

72 – 192

121

Cytoplasmic Potential

Transmembrane

193 – 215

Helical; Potential

Topological domain

216 – 218

Extracellular Potential

Transmembrane

219 – 238

Helical; Potential

Topological domain

239 – 402

164

Cytoplasmic Potential

Transmembrane

403 – 422

Helical; Potential

Topological domain

423 – 435

Extracellular Potential

Transmembrane

436 – 453

Helical; Potential

Topological domain

454 – 947

494

Cytoplasmic Potential

Transmembrane

948 – 967

Helical; Potential

Topological domain

968 – 979

Extracellular Potential

Transmembrane

980 – 997

Helical; Potential

Topological domain

998 – 1013

Cytoplasmic Potential

Transmembrane

1014 – 1034

Helical; Potential

Topological domain

1035 – 1059

Extracellular Potential

Transmembrane

1060 – 1079

Helical; Potential

Topological domain

1080 – 1092

Cytoplasmic Potential

Transmembrane

1093 – 1110

Helical; Potential

Topological domain

1111 – 1128

Extracellular Potential

Transmembrane

1129 – 1148

Helical; Potential

Topological domain

1149 – 1179

Cytoplasmic Potential

Compositional bias

1175 – 1178

Poly-Lys

Sites

Active site

491

4-aspartylphosphate intermediate By similarity

Metal binding

812

Magnesium By similarity

Metal binding

816

Magnesium By similarity

Experimental info

Sequence conflict

935

D → N in BX831910. Ref.3

Sequence conflict

995

S → F in BX831910. Ref.3

Sequences

Sequence

Length

Mass (Da)

Tools

Q9LT02 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 4A3E82D2222A4D78
Show »

FASTA

1,179

131,115

        10         20         30         40         50         60 
MSSFRVGGKV VEKVDLCRKK QLVWRLDVWP FAILYTVWLT TIVPSIDFSD ACIALGGLSA 

        70         80         90        100        110        120 
FHILVLLFTT WSVDFKCFVQ FSKVNSIDQA DACKVTPAKF SGSKEVVPLH FRSQMTDSAS 

       130        140        150        160        170        180 
SGDMEEIFFD FRKQRFIYSK ELGAFSKLPY PTKETFGHYL KCTGHGTEAK IATATEKWGR 

       190        200        210        220        230        240 
NVFDYPQPTF QKLMKENCME PFFVFQVFCV GLWCLDEFWY YSVFTLFMLF MFESTMAKSR 

       250        260        270        280        290        300 
LKTLTDLRSV RVDSQTVMVY RSGKWVKLLG TDLLPGDVVS IGRPSTQTGG EDKTVPADML 

       310        320        330        340        350        360 
LLVGSAIVNE AILTGESTPQ WKVPIVGQRS DEKLSIKRNK NHVLFGGTKI LQHSPDKSFS 

       370        380        390        400        410        420 
LKTPDGGCLA VVLRTGFETS QGKLMRTILF STERVTANSW ESGLFILFLV VFAVIAAGYV 

       430        440        450        460        470        480 
LVKGLEDPTR SKYKLLLGCS LIITSVIPPE LPMELSIAVN TSLLALVRRG IFCTEPFRIP 

       490        500        510        520        530        540 
FAGKVDLCCF DKTGTLTSDD MEFRGVGGLS NCEEAETDMS KVPVRTLEIL ASCHALVFVE 

       550        560        570        580        590        600 
NKLVGDPLEK AALKGIDWSY KADEKALPRR GNGNSVQIMQ RYHFASHLKR MSVIVRIQEE 

       610        620        630        640        650        660 
YLAFVKGAPE TIQERLVDVP AQYIETYKRY TRQGSRVLAL AYKRLPDMMV SEARDMDRDA 

       670        680        690        700        710        720 
VESDLTFAGF AVFNCPIRPD SAPVLLELKN SSHDLVMITG DQALTACHVA GQVHIVSNPV 

       730        740        750        760        770        780 
LILGRSGSGN EYKWVSPDEK EIIPYSEKEI ETLAETHDLC IGGDSIEMLQ ATSAVLRVIP 

       790        800        810        820        830        840 
FVKVFARVAP QQKELILTTF KAVGRGTLMC GDGTNDVGAL KQAHVGVALL NNKLPLSPSD 

       850        860        870        880        890        900 
SSKDDKSKSK KSKLPLEPAS KTITQNGEGS SKGKIPPQNR HLTAAELQRQ KLKKIMDDLN 

       910        920        930        940        950        960 
NDEGDGRSAP LVKLGDASMA SPFTAKHASV APVTDIIRQG RSTLVTTLQM FKILGLNCLA 

       970        980        990       1000       1010       1020 
TAYVLSVMYL DGVKLGDVQA TISGVLTAAF FLFISHARPL QTLSAERPHP SVFSVYLFLS 

      1030       1040       1050       1060       1070       1080 
LIGQFAVHLT FLVYSVKEAE KHMPEECIEP DASFHPNLVN TVSYMVSMML QVATFAVNYM 

      1090       1100       1110       1120       1130       1140 
GHPFNQSIRE NKPFFYALIA GAGFFTVIAS DLFRDLNDSL KLVPLPQGLR DKLLIWASLM 

      1150       1160       1170 
FIICYSWERL LRWAFPGKIS SWKHKQRAVT ANLEKKKKV

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H., Tabata S. DNA Res. 7:31-63(2000) [PubMed: 10718197] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Whole genome sequence comparisons and 'full-length' cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation." Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M., Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M., Weissenbach J., Salanoubat M. Genome Res. 14:406-413(2004) [PubMed: 14993207] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 702-1179. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB025633 Genomic DNA. Translation: BAA97238.1. CP002688 Genomic DNA. Translation: AED93192.1. BX831910 mRNA. No translation available.
IPI	IPI00519654.
RefSeq	NP_197752.1. NM_122268.4.
UniGene	At.25308.
3D structure databases
ProteinModelPortal	Q9LT02.
SMR	Q9LT02. Positions 544-675, 785-833.
ModBase	Search...
Proteomic databases
PRIDE	Q9LT02.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT5G23630.1; AT5G23630.1; AT5G23630.
GeneID	832428.
GenomeReviews	Gene locus AT5G23630 in contig BA000015_GR.
KEGG	ath:AT5G23630.
NMPDR	fig\|3702.1.peg.24540.
Organism-specific databases
TAIR	At5g23630.
Phylogenomic databases
eggNOG	KOG0209.
GeneTree	EPGT00050000008539.
HOGENOM	HBG316596.
InParanoid	Q9LT02.
OMA	VISCPLK.
PhylomeDB	Q9LT02.
ProtClustDB	CLSN2686295.
Gene expression databases
ArrayExpress	Q9LT02.
Genevestigator	Q9LT02.
GermOnline	AT5G23630. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR006544. ATPase_P-typ_unknown-pump-sp. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 1 hit. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 1 hit. G3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
KO	K14950.
Pfam	PF00122. E1-E2_ATPase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01494. ATPase_P-type. 2 hits. TIGR01657. P-ATPase-V. 1 hit.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATY1_ARATH

Accession

Primary (citable) accession number: Q9LT02

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 11, 2001
Last sequence update:	October 1, 2000
Last modified:	December 14, 2011
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sites

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents