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Q9LSU3 (PSA6_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proteasome subunit alpha type-6

EC=3.4.25.1
Alternative name(s):
20S proteasome alpha subunit A
20S proteasome subunit alpha-1
Gene names
Name:PAA1
Ordered Locus Names:Os03g0180400, LOC_Os03g08280
ORF Names:OSJNBa0050H14.19, OSJNBb0076N15.5
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length246 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity By similarity.

Catalytic activity

Cleavage of peptide bonds with very broad specificity.

Subunit structure

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel By similarity.

Subcellular location

Cytoplasm By similarity. Nucleus By similarity.

Sequence similarities

Belongs to the peptidase T1A family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 246246Proteasome subunit alpha type-6
PRO_0000124137

Sequences

Sequence LengthMass (Da)Tools
Q9LSU3 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: B4D9158DEA8FEDD1

FASTA24627,573
        10         20         30         40         50         60 
MSRGTGAGYD RHITIFSPEG RLYQVEYAFK AVKSAGVTSI GVRGKDSVCV VTQKKVPDKL 

        70         80         90        100        110        120 
LDHTSVTHLF PITKYIGLLA TGLTADARSL VYQARNEAAE FRFKWGYEMP VDVLAKWIAD 

       130        140        150        160        170        180 
KAQVYTQHAY MRPLGVVAMV LGYDEEKNAQ LFKCDPAGHF FGHKATSAGL KEQEAINFLE 

       190        200        210        220        230        240 
KKMKDDPQFS YEETVQIAIS ALQSVLQEDF KATEIEVGVV RKDDRVFRAL TTEEIDQHLT 


AISERD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB026558 mRNA. Translation: BAA96829.1.
AC125472 Genomic DNA. Translation: AAO13479.1.
AC126223 Genomic DNA. Translation: AAN65435.1.
RefSeqNP_001049162.1. NM_001055697.1.
UniGeneOs.3704.

3D structure databases

ProteinModelPortalQ9LSU3.
SMRQ9LSU3. Positions 2-245.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPST01.971.

Proteomic databases

PaxDbQ9LSU3.
PRIDEQ9LSU3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS03T0180400-01; OS03T0180400-01; OS03G0180400.
GeneID4331828.
KEGGosa:4331828.

Organism-specific databases

GrameneQ9LSU3.

Phylogenomic databases

eggNOGCOG0638.
HOGENOMHOG000091084.
KOK02730.

Family and domain databases

Gene3D3.60.20.10. 1 hit.
InterProIPR029055. Ntn_hydrolases_N.
IPR000426. Proteasome_asu_N.
IPR023332. Proteasome_suA-type.
IPR001353. Proteasome_sua/b.
[Graphical view]
PfamPF00227. Proteasome. 1 hit.
PF10584. Proteasome_A_N. 1 hit.
[Graphical view]
SMARTSM00948. Proteasome_A_N. 1 hit.
[Graphical view]
SUPFAMSSF56235. SSF56235. 1 hit.
PROSITEPS00388. PROTEASOME_ALPHA_1. 1 hit.
PS51475. PROTEASOME_ALPHA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePSA6_ORYSJ
AccessionPrimary (citable) accession number: Q9LSU3
Secondary accession number(s): Q7G665
Entry history
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

Peptidase families

Classification of peptidase families and list of entries