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Q9LSU0

- PSA3_ORYSJ

UniProt

Q9LSU0 - PSA3_ORYSJ

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Protein

Proteasome subunit alpha type-3

Gene
PAG1, Os01g0811100, LOC_Os01g59600, P0425G02.8, P0468B07.45
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.

GO - Molecular functioni

  1. threonine-type endopeptidase activity Source: UniProtKB-KW

GO - Biological processi

  1. response to cadmium ion Source: EnsemblPlants/Gramene
  2. response to cold Source: EnsemblPlants/Gramene
  3. ubiquitin-dependent protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Threonine protease

Enzyme and pathway databases

ReactomeiREACT_205610. Cross-presentation of soluble exogenous antigens (endosomes).
REACT_205939. Autodegradation of the E3 ubiquitin ligase COP1.
REACT_207219. APC/C:Cdc20 mediated degradation of Securin.
REACT_212204. Separation of Sister Chromatids.
REACT_214064. ER-Phagosome pathway.
REACT_219834. AUF1 (hnRNP D0) destabilizes mRNA.
REACT_223172. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome subunit alpha type-3 (EC:3.4.25.1)
Alternative name(s):
20S proteasome alpha subunit G
20S proteasome subunit alpha-7
Gene namesi
Name:PAG1
Ordered Locus Names:Os01g0811100, LOC_Os01g59600
ORF Names:P0425G02.8, P0468B07.45
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 1

Organism-specific databases

GrameneiQ9LSU0.

Subcellular locationi

Cytoplasm By similarity. Nucleus By similarity

GO - Cellular componenti

  1. apoplast Source: EnsemblPlants/Gramene
  2. cytosol Source: EnsemblPlants/Gramene
  3. nucleus Source: UniProtKB-SubCell
  4. proteasome core complex, alpha-subunit complex Source: InterPro
  5. vacuolar membrane Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus, Proteasome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 249249Proteasome subunit alpha type-3PRO_0000124099Add
BLAST

Proteomic databases

PaxDbiQ9LSU0.

Interactioni

Subunit structurei

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ9LSU0.
SMRiQ9LSU0. Positions 2-245.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase T1A family.

Phylogenomic databases

eggNOGiCOG0638.
HOGENOMiHOG000091086.
KOiK02727.
OMAiCRQGVIE.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
InterProiIPR029055. Ntn_hydrolases_N.
IPR000426. Proteasome_asu_N.
IPR023332. Proteasome_suA-type.
IPR001353. Proteasome_sua/b.
[Graphical view]
PfamiPF00227. Proteasome. 1 hit.
PF10584. Proteasome_A_N. 1 hit.
[Graphical view]
SMARTiSM00948. Proteasome_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
PROSITEiPS00388. PROTEASOME_ALPHA_1. 1 hit.
PS51475. PROTEASOME_ALPHA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LSU0-1 [UniParc]FASTAAdd to Basket

« Hide

MSSIGTGYDL SVTTFSPDGR VFQVEYATKA VDNSGTVVGI KCKDGIVLGV    50
EKLVTSKMML EGSNRRIHSV HWHSGLAVAG LAADGRQIVS RAKSEAASYE 100
KVYGEPISVK ELADRVASYV HLCTLYWWLR PFGCGVILGG YDRDGPQLYM 150
IEPSGVSYKY FGAALGKGRQ AAKTEIEKLK LSELTCREGI VEVAKIIYGV 200
HDEAKDKAFE LELSWICDES NRQHQKVPAD LLEQAKVAAQ AALEEMDAD 249
Length:249
Mass (Da):27,238
Last modified:October 1, 2000 - v1
Checksum:iE6D37062AC03E31E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB026562 mRNA. Translation: BAA96833.1.
AP003247 Genomic DNA. Translation: BAD68202.1.
AP003260 Genomic DNA. Translation: BAD68244.1.
RefSeqiNP_001044588.1. NM_001051123.1.
UniGeneiOs.3706.

Genome annotation databases

EnsemblPlantsiOS01T0811100-01; OS01T0811100-01; OS01G0811100.
OS01T0811100-02; OS01T0811100-02; OS01G0811100.
GeneIDi4327357.
KEGGiosa:4327357.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB026562 mRNA. Translation: BAA96833.1 .
AP003247 Genomic DNA. Translation: BAD68202.1 .
AP003260 Genomic DNA. Translation: BAD68244.1 .
RefSeqi NP_001044588.1. NM_001051123.1.
UniGenei Os.3706.

3D structure databases

ProteinModelPortali Q9LSU0.
SMRi Q9LSU0. Positions 2-245.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q9LSU0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS01T0811100-01 ; OS01T0811100-01 ; OS01G0811100 .
OS01T0811100-02 ; OS01T0811100-02 ; OS01G0811100 .
GeneIDi 4327357.
KEGGi osa:4327357.

Organism-specific databases

Gramenei Q9LSU0.

Phylogenomic databases

eggNOGi COG0638.
HOGENOMi HOG000091086.
KOi K02727.
OMAi CRQGVIE.

Enzyme and pathway databases

Reactomei REACT_205610. Cross-presentation of soluble exogenous antigens (endosomes).
REACT_205939. Autodegradation of the E3 ubiquitin ligase COP1.
REACT_207219. APC/C:Cdc20 mediated degradation of Securin.
REACT_212204. Separation of Sister Chromatids.
REACT_214064. ER-Phagosome pathway.
REACT_219834. AUF1 (hnRNP D0) destabilizes mRNA.
REACT_223172. Antigen processing: Ubiquitination & Proteasome degradation.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
InterProi IPR029055. Ntn_hydrolases_N.
IPR000426. Proteasome_asu_N.
IPR023332. Proteasome_suA-type.
IPR001353. Proteasome_sua/b.
[Graphical view ]
Pfami PF00227. Proteasome. 1 hit.
PF10584. Proteasome_A_N. 1 hit.
[Graphical view ]
SMARTi SM00948. Proteasome_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
PROSITEi PS00388. PROTEASOME_ALPHA_1. 1 hit.
PS51475. PROTEASOME_ALPHA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Primary structural features of the 20S proteasome subunits of rice (Oryza sativa)."
    Sassa H., Oguchi S., Inoue T., Hirano H.
    Gene 250:61-66(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Nipponbare.
  2. "The genome sequence and structure of rice chromosome 1."
    Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.
    , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
    Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiPSA3_ORYSJ
AccessioniPrimary (citable) accession number: Q9LSU0
Secondary accession number(s): Q5VQP2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: October 1, 2000
Last modified: September 3, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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