Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

ABC transporter B family member 16

Gene

ABCB16

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi381 – 388ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1016 – 1023ATP 2PROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT3G28360-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter B family member 16
Short name:
ABC transporter ABCB.16
Short name:
AtABCB16
Alternative name(s):
Multidrug resistance protein 18
P-glycoprotein 16
Gene namesi
Name:ABCB16
Synonyms:MDR18, PGP16
Ordered Locus Names:At3g28360
ORF Names:MFJ20.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G28360.

Subcellular locationi

  • Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 42HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei69 – 89HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei145 – 167HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei171 – 193HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei251 – 271HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei283 – 303HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei667 – 687HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei700 – 720HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei781 – 801HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei805 – 825HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei881 – 901HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei920 – 940HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002279291 – 1228ABC transporter B family member 16Add BLAST1228

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi529N-linked (GlcNAc...)Sequence analysis1
Glycosylationi593N-linked (GlcNAc...)Sequence analysis1
Glycosylationi628N-linked (GlcNAc...)Sequence analysis1
Glycosylationi755N-linked (GlcNAc...)Sequence analysis1
Glycosylationi827N-linked (GlcNAc...)Sequence analysis1
Glycosylationi1001N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9LSJ8.
PRIDEiQ9LSJ8.

Expressioni

Gene expression databases

GenevisibleiQ9LSJ8. AT.

Interactioni

Protein-protein interaction databases

BioGridi7794. 7 interactors.
MINTiMINT-8069481.
STRINGi3702.AT3G28360.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LSJ8.
SMRiQ9LSJ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 311ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST290
Domaini346 – 582ABC transporter 1PROSITE-ProRule annotationAdd BLAST237
Domaini658 – 946ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST289
Domaini981 – 1219ABC transporter 2PROSITE-ProRule annotationAdd BLAST239

Sequence similaritiesi

Contains 2 ABC transmembrane type-1 domains.PROSITE-ProRule annotation
Contains 2 ABC transporter domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
InParanoidiQ9LSJ8.
KOiK05658.
OMAiEVNARRI.
OrthoDBiEOG093600PV.
PhylomeDBiQ9LSJ8.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LSJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTWGSMRSI FMHADGVDWM LMGLGLIGAV GDGFITPILF FITAMLLNDF
60 70 80 90 100
GSFSFNDETF MQPISKNALA MLYVACASWV ICFLEGYCWT RTGERQAAKM
110 120 130 140 150
RERYLRAVLR QDVGYFDLHV TSTSDIITSV SSDSLVIQDF LSEKLPNILM
160 170 180 190 200
NASAFVGSYI VGFMLLWRLT IVGFPFIILL LIPGLMYGRA LIGISRKIRE
210 220 230 240 250
EYNEAGSIAE QAISSVRTVY AFVSEKKMIE KFSDALQGSV KLGLRQGLAK
260 270 280 290 300
GIAIGSNGIV YAIWGFLTWY GSRMVMNYGY KGGTVSTVTV CVTFGGTALG
310 320 330 340 350
QALSNLKYFS EAFVAGERIQ KMIKRVPDID SDNLNGHILE TIRGEVEFNN
360 370 380 390 400
VKCKYPSRPE TLIFDDLCLK IPSGKTVALV GGSGSGKSTV ISLLQRFYDP
410 420 430 440 450
NEGDILIDSV SINNMQVKWL RSQMGMVSQE PSLFATSIKE NILFGKEDAS
460 470 480 490 500
FDEVVEAAKA SNAHNFISQF PHGYQTQVGE RGVHMSGGQK QRIAIARALI
510 520 530 540 550
KSPIILLLDE ATSALDLESE RVVQEALDNA SVGRTTIVIA HRLSTIRNAD
560 570 580 590 600
IICVLHNGCI VETGSHDKLM EIDGKYTSLV RLQQMKNEES CDNTSVGVKE
610 620 630 640 650
GRVSSLRNDL DYNPRDLAHS MSSSIVTNLS DSIPQDKKPL VPSFKRLMAM
660 670 680 690 700
NRPEWKHALC GCLSASLGGA VQPIYAYSSG LMISVFFLTN HEQIKENTRI
710 720 730 740 750
YVLLFFGLAL FTFFTSISQQ YSFSYMGEYL TKRIREQMLS KILTFEVNWF
760 770 780 790 800
DEEENSSGAI CSRLAKDANV VRSLVGERMS LLVQTISTVM VACTIGLVIA
810 820 830 840 850
WRFTIVMISV QPVIIVCYYI QRVLLKNMSK KAIIAQDESS KLAAEAVSNI
860 870 880 890 900
RTITTFSSQE RIMKLLERVQ EGPRRESARQ SWLAGIMLGT TQSLITCTSA
910 920 930 940 950
LNFWYGGKLI ADGKMVSKAF FELFLIFKTT GRAIAEAGTM TTDLAKGSNS
960 970 980 990 1000
VDSVFTVLDR RTTIEPENPD GYILEKIKGQ ITFLNVDFAY PTRPNMVIFN
1010 1020 1030 1040 1050
NFSIEIHEGK STAIVGPSRS GKSTVIGLIE RFYDPLQGIV KIDGRDIRSY
1060 1070 1080 1090 1100
HLRSLRQHMS LVSQEPTLFA GTIRENIMYG RASNKIDESE IIEAGKTANA
1110 1120 1130 1140 1150
HEFITSLSDG YDTYCGDRGV QLSGGQKQRI AIARTILKNP SILLLDEATS
1160 1170 1180 1190 1200
ALDSQSERVV QDALEHVMVG KTSVVIAHRL STIQNCDTIA VLDKGKVVES
1210 1220
GTHASLLAKG PTGSYFSLVS LQRKVRYV
Length:1,228
Mass (Da):135,916
Last modified:October 1, 2000 - v1
Checksum:iB1FE531C4DF920CB
GO

Sequence cautioni

The sequence AAL91219 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026644 Genomic DNA. Translation: BAB02852.1.
CP002686 Genomic DNA. Translation: AEE77437.1.
AY081330 mRNA. Translation: AAL91219.1. Different initiation.
BT008368 mRNA. Translation: AAP37727.1.
RefSeqiNP_189477.4. NM_113756.5.
UniGeneiAt.42811.

Genome annotation databases

EnsemblPlantsiAT3G28360.1; AT3G28360.1; AT3G28360.
GeneIDi822465.
GrameneiAT3G28360.1; AT3G28360.1; AT3G28360.
KEGGiath:AT3G28360.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026644 Genomic DNA. Translation: BAB02852.1.
CP002686 Genomic DNA. Translation: AEE77437.1.
AY081330 mRNA. Translation: AAL91219.1. Different initiation.
BT008368 mRNA. Translation: AAP37727.1.
RefSeqiNP_189477.4. NM_113756.5.
UniGeneiAt.42811.

3D structure databases

ProteinModelPortaliQ9LSJ8.
SMRiQ9LSJ8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi7794. 7 interactors.
MINTiMINT-8069481.
STRINGi3702.AT3G28360.1.

Proteomic databases

PaxDbiQ9LSJ8.
PRIDEiQ9LSJ8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G28360.1; AT3G28360.1; AT3G28360.
GeneIDi822465.
GrameneiAT3G28360.1; AT3G28360.1; AT3G28360.
KEGGiath:AT3G28360.

Organism-specific databases

TAIRiAT3G28360.

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
InParanoidiQ9LSJ8.
KOiK05658.
OMAiEVNARRI.
OrthoDBiEOG093600PV.
PhylomeDBiQ9LSJ8.

Enzyme and pathway databases

BioCyciARA:AT3G28360-MONOMER.

Miscellaneous databases

PROiQ9LSJ8.

Gene expression databases

GenevisibleiQ9LSJ8. AT.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAB16B_ARATH
AccessioniPrimary (citable) accession number: Q9LSJ8
Secondary accession number(s): Q8RXD2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: October 1, 2000
Last modified: November 2, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.