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Protein

ABC transporter B family member 17

Gene

ABCB17

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi394 – 4018ATP 1PROSITE-ProRule annotation
Nucleotide bindingi1030 – 10378ATP 2PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT3G28380-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter B family member 17
Short name:
ABC transporter ABCB.17
Short name:
AtABCB17
Alternative name(s):
P-glycoprotein 17
Putative multidrug resistance protein 19
Gene namesi
Name:ABCB17
Synonyms:MDR19, PGP17
Ordered Locus Names:At3g28380
ORF Names:MFJ20.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G28380.

Subcellular locationi

  • Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei36 – 5621HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei81 – 10121HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei158 – 18023HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei184 – 20623HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei264 – 28421HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei296 – 31621HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei681 – 70121HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei714 – 73421HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei793 – 81523HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei817 – 83923HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei896 – 91924HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei923 – 94321HelicalPROSITE-ProRule annotationAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: TAIR
  • plasmodesma Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12401240ABC transporter B family member 17PRO_0000227930Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi70 – 701N-linked (GlcNAc...)Sequence analysis
Glycosylationi542 – 5421N-linked (GlcNAc...)Sequence analysis
Glycosylationi609 – 6091N-linked (GlcNAc...)Sequence analysis
Glycosylationi642 – 6421N-linked (GlcNAc...)Sequence analysis
Glycosylationi769 – 7691N-linked (GlcNAc...)Sequence analysis
Glycosylationi1015 – 10151N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9LSJ6.
PRIDEiQ9LSJ6.

Expressioni

Gene expression databases

GenevisibleiQ9LSJ6. AT.

Interactioni

Protein-protein interaction databases

BioGridi7796. 1 interaction.
MINTiMINT-8069518.
STRINGi3702.AT3G28380.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LSJ6.
SMRiQ9LSJ6. Positions 19-598, 656-1238.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini35 – 324290ABC transmembrane type-1 1PROSITE-ProRule annotationAdd
BLAST
Domaini359 – 595237ABC transporter 1PROSITE-ProRule annotationAdd
BLAST
Domaini672 – 960289ABC transmembrane type-1 2PROSITE-ProRule annotationAdd
BLAST
Domaini995 – 1233239ABC transporter 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 ABC transmembrane type-1 domains.PROSITE-ProRule annotation
Contains 2 ABC transporter domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
InParanoidiQ9LSJ6.
KOiK05658.
OMAiVAWERIL.
OrthoDBiEOG093600PV.
PhylomeDBiQ9LSJ6.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LSJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKEDEKESG RDKMKSFGSI RSIFMHADGV DWILMALGLI GAVGDGFITP
60 70 80 90 100
VVVFIFNTLL NNLGTSSSNN KTFMQTISKN VVALLYVACG SWVICFLEGY
110 120 130 140 150
CWTRTGERQA ARMREKYLRA VLRQDVGYFD LHVTSTSDVI TSISSDSLVI
160 170 180 190 200
QDFLSEKLPN FLMNASAFVA SYIVSFILMW RLTIVGFPFI ILLLVPGLMY
210 220 230 240 250
GRALVSISRK IHEQYNEAGS IAEQAISSVR TVYAFGSENK MIGKFSTALR
260 270 280 290 300
GSVKLGLRQG LAKGITIGSN GVTHAIWAFL TWYGSRLVMN HGSKGGTVFV
310 320 330 340 350
VISCITYGGV SLGQSLSNLK YFSEAFVAWE RILEVIKRVP DIDSNKKEGQ
360 370 380 390 400
ILERMKGEVE FNHVKFTYLS RPETTIFDDL CLKIPAGKTV ALVGGSGSGK
410 420 430 440 450
STVISLLQRF YDPIAGEILI DGVSIDKLQV NWLRSQMGLV SQEPVLFATS
460 470 480 490 500
ITENILFGKE DASLDEVVEA AKASNAHTFI SQFPLGYKTQ VGERGVQMSG
510 520 530 540 550
GQKQRIAIAR AIIKSPKILL LDEATSALDS ESERVVQESL DNASIGRTTI
560 570 580 590 600
VIAHRLSTIR NADVICVIHN GQIVETGSHE ELLKRIDGQY TSLVSLQQME
610 620 630 640 650
NEESNVNINV SVTKDQVMSL SKDFKYSQHN SIGSTSSSIV TNVSDLIPND
660 670 680 690 700
NQPLVPSFTR LMVMNRPEWK HALYGCLSAA LVGVLQPVSA YSAGSVISVF
710 720 730 740 750
FLTSHDQIKE KTRIYVLLFV GLAIFSFLVN ISQHYGFAYM GEYLTKRIRE
760 770 780 790 800
QMLSKILTFE VNWFDIDDNS SGAICSRLAK DANVVRSMVG DRMSLLVQTI
810 820 830 840 850
SAVIIACIIG LVIAWRLAIV MISVQPLIVV CFYTQRVLLK SLSEKASKAQ
860 870 880 890 900
DESSKLAAEA VSNIRTITAF SSQERIIKLL KKVQEGPRRE SVHRSWLAGI
910 920 930 940 950
VLGTSRSLIT CTSALNFWYG GRLIADGKIV SKAFFEIFLI FVTTGRVIAD
960 970 980 990 1000
AGTMTTDLAR GLDAVGSVFA VLDRCTTIEP KNPDGYVAEK IKGQITFLNV
1010 1020 1030 1040 1050
DFAYPTRPDV VIFENFSIEI DEGKSTAIVG TSGSGKSTII GLIERFYDPL
1060 1070 1080 1090 1100
KGTVKIDGRD IRSYHLRSLR KYISLVSQEP MLFAGTIREN IMYGGTSDKI
1110 1120 1130 1140 1150
DESEIIEAAK AANAHDFITS LSNGYDTNCG DKGVQLSGGQ KQRIAIARAV
1160 1170 1180 1190 1200
LKNPSVLLLD EATSALDSKS ERVVQDALER VMVGRTSIMI AHRLSTIQNC
1210 1220 1230 1240
DMIVVLGKGK IVESGTHSSL LEKGPTGTYF SLAGIQRTLC
Length:1,240
Mass (Da):136,062
Last modified:October 1, 2000 - v1
Checksum:iB063D89077179AB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026644 Genomic DNA. Translation: BAB02854.1.
CP002686 Genomic DNA. Translation: AEE77439.1.
RefSeqiNP_189479.1. NM_113758.1.
UniGeneiAt.53537.

Genome annotation databases

EnsemblPlantsiAT3G28380.1; AT3G28380.1; AT3G28380.
GeneIDi822467.
GrameneiAT3G28380.1; AT3G28380.1; AT3G28380.
KEGGiath:AT3G28380.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026644 Genomic DNA. Translation: BAB02854.1.
CP002686 Genomic DNA. Translation: AEE77439.1.
RefSeqiNP_189479.1. NM_113758.1.
UniGeneiAt.53537.

3D structure databases

ProteinModelPortaliQ9LSJ6.
SMRiQ9LSJ6. Positions 19-598, 656-1238.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi7796. 1 interaction.
MINTiMINT-8069518.
STRINGi3702.AT3G28380.1.

Proteomic databases

PaxDbiQ9LSJ6.
PRIDEiQ9LSJ6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G28380.1; AT3G28380.1; AT3G28380.
GeneIDi822467.
GrameneiAT3G28380.1; AT3G28380.1; AT3G28380.
KEGGiath:AT3G28380.

Organism-specific databases

TAIRiAT3G28380.

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
InParanoidiQ9LSJ6.
KOiK05658.
OMAiVAWERIL.
OrthoDBiEOG093600PV.
PhylomeDBiQ9LSJ6.

Enzyme and pathway databases

BioCyciARA:AT3G28380-MONOMER.

Miscellaneous databases

PROiQ9LSJ6.

Gene expression databases

GenevisibleiQ9LSJ6. AT.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAB17B_ARATH
AccessioniPrimary (citable) accession number: Q9LSJ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: October 1, 2000
Last modified: September 7, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.