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Protein

ABC transporter B family member 17

Gene

ABCB17

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi394 – 401ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1030 – 1037ATP 2PROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT3G28380-MONOMER
ReactomeiR-ATH-159418 Recycling of bile acids and salts
R-ATH-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
R-ATH-382556 ABC-family proteins mediated transport

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter B family member 17
Short name:
ABC transporter ABCB.17
Short name:
AtABCB17
Alternative name(s):
P-glycoprotein 17
Putative multidrug resistance protein 19
Gene namesi
Name:ABCB17
Synonyms:MDR19, PGP17
Ordered Locus Names:At3g28380
ORF Names:MFJ20.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G28380
TAIRilocus:2088927 AT3G28380

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 56HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei81 – 101HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei158 – 180HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei184 – 206HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei264 – 284HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei296 – 316HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei681 – 701HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei714 – 734HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei793 – 815HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei817 – 839HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei896 – 919HelicalPROSITE-ProRule annotationAdd BLAST24
Transmembranei923 – 943HelicalPROSITE-ProRule annotationAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002279301 – 1240ABC transporter B family member 17Add BLAST1240

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi70N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi542N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi609N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi642N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi769N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1015N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9LSJ6
PRIDEiQ9LSJ6

Expressioni

Gene expression databases

ExpressionAtlasiQ9LSJ6 differential
GenevisibleiQ9LSJ6 AT

Interactioni

Protein-protein interaction databases

BioGridi7796, 1 interactor
STRINGi3702.AT3G28380.1

Structurei

3D structure databases

ProteinModelPortaliQ9LSJ6
SMRiQ9LSJ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 324ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST290
Domaini359 – 595ABC transporter 1PROSITE-ProRule annotationAdd BLAST237
Domaini672 – 960ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST289
Domaini995 – 1233ABC transporter 2PROSITE-ProRule annotationAdd BLAST239

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0055 Eukaryota
COG1132 LUCA
InParanoidiQ9LSJ6
KOiK05658
OMAiVAWERIL
OrthoDBiEOG093600PV
PhylomeDBiQ9LSJ6

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequencei

Sequence statusi: Complete.

Q9LSJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKEDEKESG RDKMKSFGSI RSIFMHADGV DWILMALGLI GAVGDGFITP
60 70 80 90 100
VVVFIFNTLL NNLGTSSSNN KTFMQTISKN VVALLYVACG SWVICFLEGY
110 120 130 140 150
CWTRTGERQA ARMREKYLRA VLRQDVGYFD LHVTSTSDVI TSISSDSLVI
160 170 180 190 200
QDFLSEKLPN FLMNASAFVA SYIVSFILMW RLTIVGFPFI ILLLVPGLMY
210 220 230 240 250
GRALVSISRK IHEQYNEAGS IAEQAISSVR TVYAFGSENK MIGKFSTALR
260 270 280 290 300
GSVKLGLRQG LAKGITIGSN GVTHAIWAFL TWYGSRLVMN HGSKGGTVFV
310 320 330 340 350
VISCITYGGV SLGQSLSNLK YFSEAFVAWE RILEVIKRVP DIDSNKKEGQ
360 370 380 390 400
ILERMKGEVE FNHVKFTYLS RPETTIFDDL CLKIPAGKTV ALVGGSGSGK
410 420 430 440 450
STVISLLQRF YDPIAGEILI DGVSIDKLQV NWLRSQMGLV SQEPVLFATS
460 470 480 490 500
ITENILFGKE DASLDEVVEA AKASNAHTFI SQFPLGYKTQ VGERGVQMSG
510 520 530 540 550
GQKQRIAIAR AIIKSPKILL LDEATSALDS ESERVVQESL DNASIGRTTI
560 570 580 590 600
VIAHRLSTIR NADVICVIHN GQIVETGSHE ELLKRIDGQY TSLVSLQQME
610 620 630 640 650
NEESNVNINV SVTKDQVMSL SKDFKYSQHN SIGSTSSSIV TNVSDLIPND
660 670 680 690 700
NQPLVPSFTR LMVMNRPEWK HALYGCLSAA LVGVLQPVSA YSAGSVISVF
710 720 730 740 750
FLTSHDQIKE KTRIYVLLFV GLAIFSFLVN ISQHYGFAYM GEYLTKRIRE
760 770 780 790 800
QMLSKILTFE VNWFDIDDNS SGAICSRLAK DANVVRSMVG DRMSLLVQTI
810 820 830 840 850
SAVIIACIIG LVIAWRLAIV MISVQPLIVV CFYTQRVLLK SLSEKASKAQ
860 870 880 890 900
DESSKLAAEA VSNIRTITAF SSQERIIKLL KKVQEGPRRE SVHRSWLAGI
910 920 930 940 950
VLGTSRSLIT CTSALNFWYG GRLIADGKIV SKAFFEIFLI FVTTGRVIAD
960 970 980 990 1000
AGTMTTDLAR GLDAVGSVFA VLDRCTTIEP KNPDGYVAEK IKGQITFLNV
1010 1020 1030 1040 1050
DFAYPTRPDV VIFENFSIEI DEGKSTAIVG TSGSGKSTII GLIERFYDPL
1060 1070 1080 1090 1100
KGTVKIDGRD IRSYHLRSLR KYISLVSQEP MLFAGTIREN IMYGGTSDKI
1110 1120 1130 1140 1150
DESEIIEAAK AANAHDFITS LSNGYDTNCG DKGVQLSGGQ KQRIAIARAV
1160 1170 1180 1190 1200
LKNPSVLLLD EATSALDSKS ERVVQDALER VMVGRTSIMI AHRLSTIQNC
1210 1220 1230 1240
DMIVVLGKGK IVESGTHSSL LEKGPTGTYF SLAGIQRTLC
Length:1,240
Mass (Da):136,062
Last modified:October 1, 2000 - v1
Checksum:iB063D89077179AB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026644 Genomic DNA Translation: BAB02854.1
CP002686 Genomic DNA Translation: AEE77439.1
RefSeqiNP_189479.1, NM_113758.2

Genome annotation databases

EnsemblPlantsiAT3G28380.1; AT3G28380.1; AT3G28380
GeneIDi822467
GrameneiAT3G28380.1; AT3G28380.1; AT3G28380
KEGGiath:AT3G28380

Similar proteinsi

Entry informationi

Entry nameiAB17B_ARATH
AccessioniPrimary (citable) accession number: Q9LSJ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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