Q9LSC2 (Y3589_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
PTI1-like tyrosine-protein kinase At3g15890
EC=2.7.10.2

Gene names

Ordered Locus Names:	At3g15890
ORF Names:	MVC8.1

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	361 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Sequence similarities	Belongs to the protein kinase superfamily. Tyr protein kinase family. Contains 1 protein kinase domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase Tyrosine-protein kinase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	plasma membrane Inferred from direct assay Ref.4. Source: TAIR
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW non-membrane spanning protein tyrosine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 361	361	PTI1-like tyrosine-protein kinase At3g15890		PRO_0000403326
Regions
	Domain	39 – 328	290	Protein kinase
	Nucleotide binding	45 – 53	9	ATP By similarity
Sites
	Active site	165	1	Proton acceptor By similarity
	Binding site	67	1	ATP By similarity
Experimental info
	Sequence conflict	4	1	L → F in AAM65900. Ref.3
	Sequence conflict	144	1	I → M in AAM65900. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q9LSC2 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 2211DC8959934CF2	FASTA	361	40,955
	10 20 30 40 50 60 MQLLNSCCGK GFDGKKKEKE EPSWRVFSLK ELHAATNSFN YDNKLGEGRF GSVYWGQLWD 70 80 90 100 110 120 GSQIAVKRLK EWSNREEIDF AVEVEILARI RHKNLLSVRG YCAEGQERLL VYEYMQNLSL 130 140 150 160 170 180 VSHLHGQHSA ECLLDWTKRM KIAISSAQAI AYLHDHATPH IVHGDVRASN VLLDSEFEAR 190 200 210 220 230 240 VTDFGYGKLM PDDDTGDGAT KAKSNNGYIS PECDASGKES ETSDVYSFGI LLMVLVSGKR 250 260 270 280 290 300 PLERLNPTTT RCITEWVLPL VYERNFGEIV DKRLSEEHVA EKLKKVVLVG LMCAQTDPDK 310 320 330 340 350 360 RPTMSEVVEM LVNESKEKIS ELEANPLFKN PYSSNENNRE HVAEESSDVI LEDKDHQQQQ E

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones." Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S. DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[4]	"A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome." Marmagne A., Ferro M., Meinnel T., Bruley C., Kuhn L., Garin J., Barbier-Brygoo H., Ephritikhine G. Mol. Cell. Proteomics 6:1980-1996(2007) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Web resources

PlantP kinase Classification PPC

Arabidopsis protein tyrosine kinases

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB026653 Genomic DNA. Translation: BAB02873.1. CP002686 Genomic DNA. Translation: AEE75743.1. AY088361 mRNA. Translation: AAM65900.1.
IPI	IPI00527679.
RefSeq	NP_566530.1. NM_112459.1.
UniGene	At.38974. At.66462.
3D structure databases
ProteinModelPortal	Q9LSC2.
SMR	Q9LSC2. Positions 10-354.
ModBase	Search...
Proteomic databases
PaxDb	Q9LSC2.
PRIDE	Q9LSC2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT3G15890.1; AT3G15890.1; AT3G15890.
GeneID	820832.
KEGG	ath:AT3G15890.
Organism-specific databases
GeneFarm	2719.
TAIR	At3g15890.
Phylogenomic databases
eggNOG	COG0515.
HOGENOM	HOG000116550.
InParanoid	Q9LSC2.
OMA	QHSAECL.
PhylomeDB	Q9LSC2.
ProtClustDB	CLSN2688425.
Gene expression databases
Genevestigator	Q9LSC2.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. IPR008266. Tyr_kinase_AS. [Graphical view]
Pfam	PF07714. Pkinase_Tyr. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00109. PROTEIN_KINASE_TYR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y3589_ARATH

Accession

Primary (citable) accession number: Q9LSC2
Secondary accession number(s): Q8L9L7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 11, 2011
Last sequence update:	October 1, 2000
Last modified:	May 1, 2013
This is version 99 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program