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Q9LSC2

- Y3589_ARATH

UniProt

Q9LSC2 - Y3589_ARATH

Protein

PTI1-like tyrosine-protein kinase At3g15890

Gene

At3g15890

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 110 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.PROSITE-ProRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei67 – 671ATPPROSITE-ProRule annotation
    Active sitei165 – 1651Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi45 – 539ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. non-membrane spanning protein tyrosine kinase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Kinase, Transferase, Tyrosine-protein kinase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT3G15890-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    PTI1-like tyrosine-protein kinase At3g15890 (EC:2.7.10.2)
    Gene namesi
    Ordered Locus Names:At3g15890
    ORF Names:MVC8.1
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G15890.

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: TAIR

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 361361PTI1-like tyrosine-protein kinase At3g15890PRO_0000403326Add
    BLAST

    Proteomic databases

    PaxDbiQ9LSC2.
    PRIDEiQ9LSC2.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9LSC2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9LSC2.
    SMRiQ9LSC2. Positions 10-354.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini39 – 328290Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Tyr protein kinase family.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000116550.
    InParanoidiQ9LSC2.
    OMAiQHSAECL.
    PhylomeDBiQ9LSC2.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
    IPR008266. Tyr_kinase_AS.
    [Graphical view]
    PfamiPF07714. Pkinase_Tyr. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00109. PROTEIN_KINASE_TYR. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9LSC2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQLLNSCCGK GFDGKKKEKE EPSWRVFSLK ELHAATNSFN YDNKLGEGRF    50
    GSVYWGQLWD GSQIAVKRLK EWSNREEIDF AVEVEILARI RHKNLLSVRG 100
    YCAEGQERLL VYEYMQNLSL VSHLHGQHSA ECLLDWTKRM KIAISSAQAI 150
    AYLHDHATPH IVHGDVRASN VLLDSEFEAR VTDFGYGKLM PDDDTGDGAT 200
    KAKSNNGYIS PECDASGKES ETSDVYSFGI LLMVLVSGKR PLERLNPTTT 250
    RCITEWVLPL VYERNFGEIV DKRLSEEHVA EKLKKVVLVG LMCAQTDPDK 300
    RPTMSEVVEM LVNESKEKIS ELEANPLFKN PYSSNENNRE HVAEESSDVI 350
    LEDKDHQQQQ E 361
    Length:361
    Mass (Da):40,955
    Last modified:October 1, 2000 - v1
    Checksum:i2211DC8959934CF2
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti4 – 41L → F in AAM65900. 1 PublicationCurated
    Sequence conflicti144 – 1441I → M in AAM65900. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB026653 Genomic DNA. Translation: BAB02873.1.
    CP002686 Genomic DNA. Translation: AEE75743.1.
    AY088361 mRNA. Translation: AAM65900.1.
    RefSeqiNP_566530.1. NM_112459.1.
    UniGeneiAt.38974.
    At.66462.

    Genome annotation databases

    EnsemblPlantsiAT3G15890.1; AT3G15890.1; AT3G15890.
    GeneIDi820832.
    KEGGiath:AT3G15890.

    Cross-referencesi

    Web resourcesi

    PlantP kinase Classification PPC
    Arabidopsis protein tyrosine kinases

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB026653 Genomic DNA. Translation: BAB02873.1 .
    CP002686 Genomic DNA. Translation: AEE75743.1 .
    AY088361 mRNA. Translation: AAM65900.1 .
    RefSeqi NP_566530.1. NM_112459.1.
    UniGenei At.38974.
    At.66462.

    3D structure databases

    ProteinModelPortali Q9LSC2.
    SMRi Q9LSC2. Positions 10-354.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q9LSC2.
    PRIDEi Q9LSC2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G15890.1 ; AT3G15890.1 ; AT3G15890 .
    GeneIDi 820832.
    KEGGi ath:AT3G15890.

    Organism-specific databases

    GeneFarmi 2719.
    TAIRi AT3G15890.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000116550.
    InParanoidi Q9LSC2.
    OMAi QHSAECL.
    PhylomeDBi Q9LSC2.

    Enzyme and pathway databases

    BioCyci ARA:AT3G15890-MONOMER.

    Gene expression databases

    Genevestigatori Q9LSC2.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
    IPR008266. Tyr_kinase_AS.
    [Graphical view ]
    Pfami PF07714. Pkinase_Tyr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00109. PROTEIN_KINASE_TYR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
      Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
      DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Full-length cDNA from Arabidopsis thaliana."
      Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
      Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiY3589_ARATH
    AccessioniPrimary (citable) accession number: Q9LSC2
    Secondary accession number(s): Q8L9L7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 11, 2011
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 110 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3