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Protein

PTI1-like tyrosine-protein kinase At3g15890

Gene

At3g15890

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei67 – 671ATPPROSITE-ProRule annotation
Active sitei165 – 1651Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi45 – 539ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. non-membrane spanning protein tyrosine kinase activity Source: UniProtKB-EC
  3. peptide receptor activity Source: GO_Central
  4. transmembrane receptor protein serine/threonine kinase activity Source: GO_Central
  5. ubiquitin protein ligase binding Source: GO_Central

GO - Biological processi

  1. hormone-mediated signaling pathway Source: GO_Central
  2. protein autophosphorylation Source: GO_Central
  3. transmembrane receptor protein serine/threonine kinase signaling pathway Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase, Tyrosine-protein kinase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT3G15890-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
PTI1-like tyrosine-protein kinase At3g15890 (EC:2.7.10.2)
Gene namesi
Ordered Locus Names:At3g15890
ORF Names:MVC8.1
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G15890.

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: TAIR
  2. plasmodesma Source: GO_Central
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 361361PTI1-like tyrosine-protein kinase At3g15890PRO_0000403326Add
BLAST

Proteomic databases

PaxDbiQ9LSC2.
PRIDEiQ9LSC2.

Expressioni

Gene expression databases

GenevestigatoriQ9LSC2.

Structurei

3D structure databases

ProteinModelPortaliQ9LSC2.
SMRiQ9LSC2. Positions 10-354.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 328290Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Tyr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000116550.
InParanoidiQ9LSC2.
OMAiPEQRPIM.
PhylomeDBiQ9LSC2.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamiPF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LSC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLLNSCCGK GFDGKKKEKE EPSWRVFSLK ELHAATNSFN YDNKLGEGRF
60 70 80 90 100
GSVYWGQLWD GSQIAVKRLK EWSNREEIDF AVEVEILARI RHKNLLSVRG
110 120 130 140 150
YCAEGQERLL VYEYMQNLSL VSHLHGQHSA ECLLDWTKRM KIAISSAQAI
160 170 180 190 200
AYLHDHATPH IVHGDVRASN VLLDSEFEAR VTDFGYGKLM PDDDTGDGAT
210 220 230 240 250
KAKSNNGYIS PECDASGKES ETSDVYSFGI LLMVLVSGKR PLERLNPTTT
260 270 280 290 300
RCITEWVLPL VYERNFGEIV DKRLSEEHVA EKLKKVVLVG LMCAQTDPDK
310 320 330 340 350
RPTMSEVVEM LVNESKEKIS ELEANPLFKN PYSSNENNRE HVAEESSDVI
360
LEDKDHQQQQ E
Length:361
Mass (Da):40,955
Last modified:October 1, 2000 - v1
Checksum:i2211DC8959934CF2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti4 – 41L → F in AAM65900 (Ref. 3) Curated
Sequence conflicti144 – 1441I → M in AAM65900 (Ref. 3) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026653 Genomic DNA. Translation: BAB02873.1.
CP002686 Genomic DNA. Translation: AEE75743.1.
AY088361 mRNA. Translation: AAM65900.1.
RefSeqiNP_566530.1. NM_112459.1.
UniGeneiAt.38974.
At.66462.

Genome annotation databases

EnsemblPlantsiAT3G15890.1; AT3G15890.1; AT3G15890.
GeneIDi820832.
KEGGiath:AT3G15890.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC
Arabidopsis protein tyrosine kinases

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026653 Genomic DNA. Translation: BAB02873.1.
CP002686 Genomic DNA. Translation: AEE75743.1.
AY088361 mRNA. Translation: AAM65900.1.
RefSeqiNP_566530.1. NM_112459.1.
UniGeneiAt.38974.
At.66462.

3D structure databases

ProteinModelPortaliQ9LSC2.
SMRiQ9LSC2. Positions 10-354.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ9LSC2.
PRIDEiQ9LSC2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G15890.1; AT3G15890.1; AT3G15890.
GeneIDi820832.
KEGGiath:AT3G15890.

Organism-specific databases

GeneFarmi2719.
TAIRiAT3G15890.

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000116550.
InParanoidiQ9LSC2.
OMAiPEQRPIM.
PhylomeDBiQ9LSC2.

Enzyme and pathway databases

BioCyciARA:AT3G15890-MONOMER.

Miscellaneous databases

PROiQ9LSC2.

Gene expression databases

GenevestigatoriQ9LSC2.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamiPF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
    Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
    DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiY3589_ARATH
AccessioniPrimary (citable) accession number: Q9LSC2
Secondary accession number(s): Q8L9L7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: October 1, 2000
Last modified: April 29, 2015
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.