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Q9LRZ4 (P2C41_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 41

Short name=AtPP2C41
EC=3.1.3.16
Gene names
Ordered Locus Names:At3g16800
ORF Names:K20I9.2
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length351 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Ontologies

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9LRZ4-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9LRZ4-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-95: Missing.
     295-315: MWDVMTNNEAVEIVRGVKERR → VIYQTYSAFKSKSRLINHIIV
     316-351: Missing.
Note: May be due to intron retention. No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 351351Probable protein phosphatase 2C 41
PRO_0000367965

Regions

Domain169 – 309141PP2C-like

Sites

Metal binding981Manganese 1 By similarity
Metal binding981Manganese 2 By similarity
Metal binding991Manganese 1; via carbonyl oxygen By similarity
Metal binding2931Manganese 2 By similarity
Metal binding3391Manganese 2 By similarity

Natural variations

Alternative sequence1 – 9595Missing in isoform 2.
VSP_036767
Alternative sequence295 – 31521MWDVM…VKERR → VIYQTYSAFKSKSRLINHII V in isoform 2.
VSP_036768
Alternative sequence316 – 35136Missing in isoform 2.
VSP_036769

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 5161F2EA4314BFD6

FASTA35138,601
        10         20         30         40         50         60 
MVLLPAFLDG LARTVSTKKG KKLSEDEDGG REIAKSMIKD SKKNSTLLGT SGFVSSESSK 

        70         80         90        100        110        120 
RFTSICSNRG EKGINQDRAI VWEGFGCQED ITFCGMFDGH GPWGHVIAKR VKKSFPSSLL 

       130        140        150        160        170        180 
CQWQQTLASL SSSPECSSPF DLWKQACLKT FSIIDLDLKI SPSIDSYCSG CTALTAVLQG 

       190        200        210        220        230        240 
DHLVIANAGD SRAVIATTSD DGNGLVPVQL SVDFKPNIPE EAERIKQSDG RLFCLDDEPG 

       250        260        270        280        290        300 
VYRVGMPNGG SLGLAVSRAF GDYCLKDFGL VSEPEVTYRK ITDKDQFLIL ATDGMWDVMT 

       310        320        330        340        350 
NNEAVEIVRG VKERRKSAKR LVERAVTLWR RKRRSIAMDD ISVLCLFFRP S 

« Hide

Isoform 2 [UniParc].

Checksum: 8581675EA34F603A
Show »

FASTA22023,983

References

« Hide 'large scale' references
[1]"Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Strain: cv. Columbia.
[4]"Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Strain: cv. Columbia.
[5]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[6]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB028608 Genomic DNA. Translation: BAA95773.1.
CP002686 Genomic DNA. Translation: AEE75866.1.
CP002686 Genomic DNA. Translation: AEE75867.1.
AY099831 mRNA. Translation: AAM20682.1.
BT000321 mRNA. Translation: AAN15640.1.
AK317121 mRNA. Translation: BAH19809.1.
AY088376 mRNA. Translation: AAM65915.1.
RefSeqNP_188303.1. NM_112554.2. [Q9LRZ4-1]
NP_850599.2. NM_180268.3. [Q9LRZ4-1]
UniGeneAt.38836.

3D structure databases

ProteinModelPortalQ9LRZ4.
SMRQ9LRZ4. Positions 62-348.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ9LRZ4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G16800.1; AT3G16800.1; AT3G16800. [Q9LRZ4-1]
AT3G16800.2; AT3G16800.2; AT3G16800. [Q9LRZ4-1]
GeneID820933.
KEGGath:AT3G16800.

Organism-specific databases

TAIRAT3G16800.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000233897.
InParanoidQ9LRZ4.
OMARSIAMDD.
PhylomeDBQ9LRZ4.

Enzyme and pathway databases

BioCycARA:AT3G16800-MONOMER.
ARA:GQT-1053-MONOMER.
ARA:GQT-1054-MONOMER.

Gene expression databases

ArrayExpressQ9LRZ4.
GenevestigatorQ9LRZ4.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 1 hit.
ProtoNetSearch...

Entry information

Entry nameP2C41_ARATH
AccessionPrimary (citable) accession number: Q9LRZ4
Secondary accession number(s): Q8LPG8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names