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Q9LRZ4

- P2C41_ARATH

UniProt

Q9LRZ4 - P2C41_ARATH

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Protein

Probable protein phosphatase 2C 41

Gene

At3g16800

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi98 – 981Manganese 1By similarity
Metal bindingi98 – 981Manganese 2By similarity
Metal bindingi99 – 991Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi293 – 2931Manganese 2By similarity
Metal bindingi339 – 3391Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT3G16800-MONOMER.
ARA:GQT-1053-MONOMER.
ARA:GQT-1054-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 41 (EC:3.1.3.16)
Short name:
AtPP2C41
Gene namesi
Ordered Locus Names:At3g16800
ORF Names:K20I9.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 3

Organism-specific databases

TAIRiAT3G16800.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: TAIR
  2. nucleus Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 351351Probable protein phosphatase 2C 41PRO_0000367965Add
BLAST

Proteomic databases

PRIDEiQ9LRZ4.

Expressioni

Gene expression databases

ExpressionAtlasiQ9LRZ4. baseline and differential.
GenevestigatoriQ9LRZ4.

Structurei

3D structure databases

ProteinModelPortaliQ9LRZ4.
SMRiQ9LRZ4. Positions 62-348.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini169 – 309141PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233897.
InParanoidiQ9LRZ4.
OMAiRSIAMDD.
PhylomeDBiQ9LRZ4.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9LRZ4-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MVLLPAFLDG LARTVSTKKG KKLSEDEDGG REIAKSMIKD SKKNSTLLGT
60 70 80 90 100
SGFVSSESSK RFTSICSNRG EKGINQDRAI VWEGFGCQED ITFCGMFDGH
110 120 130 140 150
GPWGHVIAKR VKKSFPSSLL CQWQQTLASL SSSPECSSPF DLWKQACLKT
160 170 180 190 200
FSIIDLDLKI SPSIDSYCSG CTALTAVLQG DHLVIANAGD SRAVIATTSD
210 220 230 240 250
DGNGLVPVQL SVDFKPNIPE EAERIKQSDG RLFCLDDEPG VYRVGMPNGG
260 270 280 290 300
SLGLAVSRAF GDYCLKDFGL VSEPEVTYRK ITDKDQFLIL ATDGMWDVMT
310 320 330 340 350
NNEAVEIVRG VKERRKSAKR LVERAVTLWR RKRRSIAMDD ISVLCLFFRP

S
Length:351
Mass (Da):38,601
Last modified:October 1, 2000 - v1
Checksum:i5161F2EA4314BFD6
GO
Isoform 2 (identifier: Q9LRZ4-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-95: Missing.
     295-315: MWDVMTNNEAVEIVRGVKERR → VIYQTYSAFKSKSRLINHIIV
     316-351: Missing.

Note: May be due to intron retention. No experimental confirmation available.

Show »
Length:220
Mass (Da):23,983
Checksum:i8581675EA34F603A
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 9595Missing in isoform 2. 1 PublicationVSP_036767Add
BLAST
Alternative sequencei295 – 31521MWDVM…VKERR → VIYQTYSAFKSKSRLINHII V in isoform 2. 1 PublicationVSP_036768Add
BLAST
Alternative sequencei316 – 35136Missing in isoform 2. 1 PublicationVSP_036769Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB028608 Genomic DNA. Translation: BAA95773.1.
CP002686 Genomic DNA. Translation: AEE75866.1.
CP002686 Genomic DNA. Translation: AEE75867.1.
AY099831 mRNA. Translation: AAM20682.1.
BT000321 mRNA. Translation: AAN15640.1.
AK317121 mRNA. Translation: BAH19809.1.
AY088376 mRNA. Translation: AAM65915.1.
RefSeqiNP_188303.1. NM_112554.2. [Q9LRZ4-1]
NP_850599.2. NM_180268.3. [Q9LRZ4-1]
UniGeneiAt.38836.

Genome annotation databases

EnsemblPlantsiAT3G16800.1; AT3G16800.1; AT3G16800. [Q9LRZ4-1]
AT3G16800.2; AT3G16800.2; AT3G16800. [Q9LRZ4-1]
GeneIDi820933.
KEGGiath:AT3G16800.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB028608 Genomic DNA. Translation: BAA95773.1 .
CP002686 Genomic DNA. Translation: AEE75866.1 .
CP002686 Genomic DNA. Translation: AEE75867.1 .
AY099831 mRNA. Translation: AAM20682.1 .
BT000321 mRNA. Translation: AAN15640.1 .
AK317121 mRNA. Translation: BAH19809.1 .
AY088376 mRNA. Translation: AAM65915.1 .
RefSeqi NP_188303.1. NM_112554.2. [Q9LRZ4-1 ]
NP_850599.2. NM_180268.3. [Q9LRZ4-1 ]
UniGenei At.38836.

3D structure databases

ProteinModelPortali Q9LRZ4.
SMRi Q9LRZ4. Positions 62-348.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q9LRZ4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT3G16800.1 ; AT3G16800.1 ; AT3G16800 . [Q9LRZ4-1 ]
AT3G16800.2 ; AT3G16800.2 ; AT3G16800 . [Q9LRZ4-1 ]
GeneIDi 820933.
KEGGi ath:AT3G16800.

Organism-specific databases

TAIRi AT3G16800.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000233897.
InParanoidi Q9LRZ4.
OMAi RSIAMDD.
PhylomeDBi Q9LRZ4.

Enzyme and pathway databases

BioCyci ARA:AT3G16800-MONOMER.
ARA:GQT-1053-MONOMER.
ARA:GQT-1054-MONOMER.

Gene expression databases

ExpressionAtlasi Q9LRZ4. baseline and differential.
Genevestigatori Q9LRZ4.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
    Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
    DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Strain: cv. Columbia.
  4. "Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
    Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
    DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: cv. Columbia.
  5. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  6. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C41_ARATH
AccessioniPrimary (citable) accession number: Q9LRZ4
Secondary accession number(s): Q8LPG8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: October 29, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3