Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable protein phosphatase 2C 41

Gene

At3g16800

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi98Manganese 1By similarity1
Metal bindingi98Manganese 2By similarity1
Metal bindingi99Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi293Manganese 2By similarity1
Metal bindingi339Manganese 2By similarity1

GO - Molecular functioni

GO - Biological processi

  • drought recovery Source: TAIR
  • microtubule cytoskeleton organization Source: TAIR
  • negative regulation of growth Source: TAIR
  • protein dephosphorylation Source: TAIR

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Enzyme and pathway databases

ReactomeiR-ATH-70895 Branched-chain amino acid catabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 41 (EC:3.1.3.16)
Short name:
AtPP2C41
Gene namesi
Ordered Locus Names:At3g16800
ORF Names:K20I9.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G16800
TAIRilocus:2086755 AT3G16800

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679651 – 351Probable protein phosphatase 2C 41Add BLAST351

Proteomic databases

PaxDbiQ9LRZ4

Expressioni

Gene expression databases

ExpressionAtlasiQ9LRZ4 baseline and differential
GenevisibleiQ9LRZ4 AT

Interactioni

Protein-protein interaction databases

BioGridi6267, 1 interactor
STRINGi3702.AT3G16800.1

Structurei

3D structure databases

ProteinModelPortaliQ9LRZ4
SMRiQ9LRZ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 348PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST287

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
HOGENOMiHOG000233897
InParanoidiQ9LRZ4
OMAiDDMSAIC
OrthoDBiEOG09360GNF
PhylomeDBiQ9LRZ4

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9LRZ4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MVLLPAFLDG LARTVSTKKG KKLSEDEDGG REIAKSMIKD SKKNSTLLGT
60 70 80 90 100
SGFVSSESSK RFTSICSNRG EKGINQDRAI VWEGFGCQED ITFCGMFDGH
110 120 130 140 150
GPWGHVIAKR VKKSFPSSLL CQWQQTLASL SSSPECSSPF DLWKQACLKT
160 170 180 190 200
FSIIDLDLKI SPSIDSYCSG CTALTAVLQG DHLVIANAGD SRAVIATTSD
210 220 230 240 250
DGNGLVPVQL SVDFKPNIPE EAERIKQSDG RLFCLDDEPG VYRVGMPNGG
260 270 280 290 300
SLGLAVSRAF GDYCLKDFGL VSEPEVTYRK ITDKDQFLIL ATDGMWDVMT
310 320 330 340 350
NNEAVEIVRG VKERRKSAKR LVERAVTLWR RKRRSIAMDD ISVLCLFFRP

S
Length:351
Mass (Da):38,601
Last modified:October 1, 2000 - v1
Checksum:i5161F2EA4314BFD6
GO
Isoform 2 (identifier: Q9LRZ4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-95: Missing.
     295-315: MWDVMTNNEAVEIVRGVKERR → VIYQTYSAFKSKSRLINHIIV
     316-351: Missing.

Note: May be due to intron retention. No experimental confirmation available.
Show »
Length:220
Mass (Da):23,983
Checksum:i8581675EA34F603A
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0367671 – 95Missing in isoform 2. 1 PublicationAdd BLAST95
Alternative sequenceiVSP_036768295 – 315MWDVM…VKERR → VIYQTYSAFKSKSRLINHII V in isoform 2. 1 PublicationAdd BLAST21
Alternative sequenceiVSP_036769316 – 351Missing in isoform 2. 1 PublicationAdd BLAST36

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB028608 Genomic DNA Translation: BAA95773.1
CP002686 Genomic DNA Translation: AEE75866.1
CP002686 Genomic DNA Translation: AEE75867.1
CP002686 Genomic DNA Translation: AEE75868.2
AY099831 mRNA Translation: AAM20682.1
BT000321 mRNA Translation: AAN15640.1
AK317121 mRNA Translation: BAH19809.1
AY088376 mRNA Translation: AAM65915.1
RefSeqiNP_001319572.1, NM_001338260.1 [Q9LRZ4-1]
NP_188303.1, NM_112554.3 [Q9LRZ4-1]
NP_850599.2, NM_180268.4 [Q9LRZ4-1]
UniGeneiAt.38836

Genome annotation databases

EnsemblPlantsiAT3G16800.1; AT3G16800.1; AT3G16800 [Q9LRZ4-1]
AT3G16800.2; AT3G16800.2; AT3G16800 [Q9LRZ4-1]
AT3G16800.3; AT3G16800.3; AT3G16800 [Q9LRZ4-1]
GeneIDi820933
GrameneiAT3G16800.1; AT3G16800.1; AT3G16800 [Q9LRZ4-1]
AT3G16800.2; AT3G16800.2; AT3G16800 [Q9LRZ4-1]
AT3G16800.3; AT3G16800.3; AT3G16800 [Q9LRZ4-1]
KEGGiath:AT3G16800

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiP2C41_ARATH
AccessioniPrimary (citable) accession number: Q9LRZ4
Secondary accession number(s): Q8LPG8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health