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Reviewed, UniProtKB/Swiss-Prot Q9LRS0 (GOX1_ARATH)

Last modified February 9, 2010. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable peroxisomal (S)-2-hydroxy-acid oxidase 1
    EC=1.1.3.15
Alternative name(s):
    Glycolate oxidase 1
      Short name=GOX 1
    Short chain alpha-hydroxy acid oxidase 1
Gene names
Ordered Locus Names: At3g14415
ORF Names: MLN21.20
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidsmalvidsBrassicalesBrassicaceaeArabidopsis

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level.

General annotation (Comments)

Catalytic activity

(S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2.

Cofactor

FMN By similarity.

Pathway

Photosynthesis; photorespiration; glycine from 2-phosphoglycolate: step 2/3.

Subunit structure

Homotetramer or homooctamer By similarity.

Subcellular location

Peroxisome By similarity.

Sequence similarities

Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

Contains 1 FMN hydroxy acid dehydrogenase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 367367Probable peroxisomal (S)-2-hydroxy-acid oxidase 1
PRO_0000206323

Regions

Domain1 – 359359FMN hydroxy acid dehydrogenase
Nucleotide binding285 – 30925FMN By similarity
Motif365 – 3673Microbody targeting signal Potential

Sites

Active site2541Proton acceptor By similarity
Binding site241Substrate Potential
Binding site1061FMN By similarity
Binding site1271FMN By similarity
Binding site1291Substrate By similarity
Binding site1551FMN By similarity
Binding site1641Substrate By similarity
Binding site2301FMN By similarity
Binding site2571Substrate Potential

Sequences

Sequence LengthMass (Da)Tools
Q9LRS0-1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: C0B0F9B083F1B6E6

FASTA36740,307
        10         20         30         40         50         60 
MEITNVTEYD AIAKAKLPKM VYDYYASGAE DQWTLQENRN AFARILFRPR ILIDVNKIDM 

        70         80         90        100        110        120 
ATTVLGFKIS MPIMVAPTAF QKMAHPDGEY ATARAASAAG TIMTLSSWAT SSVEEVASTG 

       130        140        150        160        170        180 
PGIRFFQLYV YKNRKVVEQL VRRAEKAGFK AIALTVDTPR LGRRESDIKN RFTLPPNLTL 

       190        200        210        220        230        240 
KNFEGLDLGK MDEANDSGLA SYVAGQIDRT LSWKDIQWLQ TITNMPILVK GVLTGEDARI 

       250        260        270        280        290        300 
AIQAGAAGII VSNHGARQLD YVPATISALE EVVKATQGRV PVFLDGGVRR GTDVFKALAL 

       310        320        330        340        350        360 
GASGIFIGRP VVFALAAEGE AGVKKVLQML RDEFELTMAL SGCRSLSEIT RNHIVTEWDT 


PRHLPRL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB028617, AB022220 Genomic DNA. Translation: BAB01333.1.
AY058095 mRNA. Translation: AAL24203.1.
AY136402 mRNA. Translation: AAM97068.1.
BT002129 mRNA. Translation: AAN72140.1.
IPIIPI00518426.
RefSeqNP_188059.1.
UniGeneAt.20363
At.67927
Rra.4802

3D structure databases

SMRQ9LRS0. Positions 1-359.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9LRS0.

Proteomic databases

PRIDEQ9LRS0.
ProMEXQ9LRS0.

Genome annotation databases

GeneID820664.
GenomeReviewsGene locus AT3G14415 in contig BA000014_GR.
KEGGath:AT3G14415.
NMPDRfig|3702.1.peg.13578.

Organism-specific databases

TAIRAt3g14415.

Phylogenomic databases

HOGENOMHBG517781.
InParanoidQ9LRS0.
OMAMITCREN.
PhylomeDBQ9LRS0.

Enzyme and pathway databases

BRENDA1.1.3.15. 302.

Gene expression databases

ArrayExpressQ9LRS0.
GenevestigatorQ9LRS0.
GermOnlineAT3G14415. Arabidopsis thaliana.

Family and domain databases

InterProIPR012133. a-Hydoxy_acid_DH_FMN.
IPR013785. Aldolase_TIM.
IPR000262. FMN-dep_DH.
IPR008259. FMN_hydac_DH_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PfamPF01070. FMN_dh. 1 hit.
[Graphical view]
PIRSFPIRSF000138. Al-hdrx_acd_dh. 1 hit.
PROSITEPS00557. FMN_HYDROXY_ACID_DH_1. 1 hit.
PS51349. FMN_HYDROXY_ACID_DH_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGOX1_ARATH
AccessionPrimary (citable) accession number: Q9LRS0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: October 1, 2000
Last modified: February 9, 2010
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents