Q9LRA7 (TPS9_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 9
EC=2.4.1.15

Alternative name(s):
Trehalose-6-phosphate synthase 9
Short name=AtTPS9

Gene names

Name:	TPS9
Ordered Locus Names:	At1g23870
ORF Names:	T23E23.3

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	867 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.
Sequence similarities	In the N-terminal section; belongs to the glycosyltransferase 20 family. In the C-terminal section; belongs to the trehalose phosphatase family.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	trehalose biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 867	867	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 9		PRO_0000324830
Regions
	Region	59 – 546	488	Glycosyltransferase
Amino acid modifications
	Modified residue	395	1	Phosphoserine Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Q9LRA7 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 606736BC2B78FE81	FASTA	867	98,496
	10 20 30 40 50 60 MVSRSCANFL DLASWDLLDF PQTQRALPRV MTVPGIISEL DGGYSDGSSD VNSSNSSRER 70 80 90 100 110 120 KIIVANMLPL QAKRDTETGQ WCFSWDEDSL LLQLRDGFSS DTEFVYIGSL NADIGISEQE 130 140 150 160 170 180 EVSHKLLLDF NCVPTFLPKE MQEKFYLGFC KHHLWPLFHY MLPMFPDHGD RFDRRLWQAY 190 200 210 220 230 240 VSANKIFSDR VMEVINPEED YVWIHDYHLM VLPTFLRKRF NRIKLGFFLH SPFPSSEIYR 250 260 270 280 290 300 TLPVRDDLLR GLLNCDLIGF HTFDYARHFL SCCSRMLGLD YESKRGHIGL DYFGRTVFIK 310 320 330 340 350 360 ILPVGIHMGR LESVLNLPST AAKMKEIQEQ FKGKKLILGV DDMDIFKGIS LKLIAMERLF 370 380 390 400 410 420 ETYWHMRGKL VLIQIVNPAR ATGKDVEEAK KETYSTAKRI NERYGSAGYQ PVILIDRLVP 430 440 450 460 470 480 RYEKTAYYAM ADCCLVNAVR DGMNLVPYKY IICRQGTPGM DKAMGISHDS ARTSMLVVSE 490 500 510 520 530 540 FIGCSPSLSG AIRVNPWDVD AVAEAVNLAL TMGETEKRLR HEKHYHYVST HDVGYWAKSF 550 560 570 580 590 600 MQDLERACRE HYNKRCWGIG FGLSFRVLSL SPSFRKLSID HIVSTYRNTQ RRAIFLDYDG 610 620 630 640 650 660 TLVPESSIIK TPNAEVLSVL KSLCGDPKNT VFVVSGRGWE SLSDWLSPCE NLGIAAEHGY 670 680 690 700 710 720 FIRWSSKKEW ETCYSSAEAE WKTMVEPVMR SYMDATDGST IEYKESALVW HHQDADPDFG 730 740 750 760 770 780 ACQAKELLDH LESVLANEPV VVKRGQHIVE VKPQGVSKGL AVEKVIHQMV EDGNPPDMVM 790 800 810 820 830 840 CIGDDRSDED MFESILSTVT NPDLPMPPEI FACTVGRKPS KAKYFLDDVS DVLKLLGGLA 850 860 AATSSSKPEY QQQSSSLHTQ VAFESII

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana." Leyman B., Van Dijck P., Thevelein J.M. Trends Plant Sci. 6:510-513(2001) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.
[5]	"Temporal analysis of sucrose-induced phosphorylation changes in plasma membrane proteins of Arabidopsis." Niittylae T., Fuglsang A.T., Palmgren M.G., Frommer W.B., Schulze W.X. Mol. Cell. Proteomics 6:1711-1726(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-395, MASS SPECTROMETRY. Tissue: Seedling.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC002423 Genomic DNA. Translation: AAF87136.1. CP002684 Genomic DNA. Translation: AEE30444.1. AY072210 mRNA. Translation: AAL60031.1. AY096366 mRNA. Translation: AAM20007.1.
IPI	IPI00537349.
RefSeq	NP_173799.1. NM_102235.2.
UniGene	At.41515. At.48224.
3D structure databases
HSSP	HSSP built from PDB template 1UQT based on UniProtKB P31677.
ProteinModelPortal	Q9LRA7.
SMR	Q9LRA7. Positions 137-546.
ModBase	Search...
Protein-protein interaction databases
STRING	3702.AT1G23870.1-P.
Protein family/group databases
CAZy	GT20. Glycosyltransferase Family 20.
Proteomic databases
PaxDb	Q9LRA7.
PRIDE	Q9LRA7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G23870.1; AT1G23870.1; AT1G23870.
GeneID	838998.
KEGG	ath:AT1G23870.
Organism-specific databases
TAIR	At1g23870.
Phylogenomic databases
eggNOG	COG0380.
HOGENOM	HOG000191476.
InParanoid	Q9LRA7.
KO	K16055.
OMA	ACQINEV.
PhylomeDB	Q9LRA7.
ProtClustDB	CLSN2679729.
Gene expression databases
Genevestigator	Q9LRA7.
Family and domain databases
Gene3D	3.40.50.1000. 2 hits.
InterPro	IPR001830. Glyco_trans_20. IPR023214. HAD-like_dom. IPR006379. HAD-SF_hydro_IIB. IPR003337. Trehalose_PPase. [Graphical view]
Pfam	PF00982. Glyco_transf_20. 1 hit. PF02358. Trehalose_PPase. 1 hit. [Graphical view]
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01484. HAD-SF-IIB. 1 hit. TIGR00685. T6PP. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TPS9_ARATH

Accession

Primary (citable) accession number: Q9LRA7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	October 1, 2000
Last modified:	May 1, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program