Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable protein phosphatase 2C 1

Gene

PPC6-6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May act as negative regulator of GCN5.1 Publication

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi95Manganese 1By similarity1
Metal bindingi95Manganese 2By similarity1
Metal bindingi96Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi307Manganese 2By similarity1
Metal bindingi353Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Enzyme and pathway databases

ReactomeiR-ATH-70895 Branched-chain amino acid catabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 1 (EC:3.1.3.16)
Short name:
AtPP2C01
Alternative name(s):
AtPPC6;6
Gene namesi
Name:PPC6-6
Ordered Locus Names:At1g03590
ORF Names:F21B7.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G03590
TAIRilocus:2020863 AT1G03590

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679351 – 462Probable protein phosphatase 2C 1Add BLAST462

Proteomic databases

PaxDbiQ9LR65
PRIDEiQ9LR65

PTM databases

iPTMnetiQ9LR65

Expressioni

Gene expression databases

ExpressionAtlasiQ9LR65 baseline and differential
GenevisibleiQ9LR65 AT

Interactioni

Subunit structurei

Interacts with GCN5.1 Publication

Protein-protein interaction databases

BioGridi24682, 1 interactor
STRINGi3702.AT1G03590.1

Structurei

3D structure databases

ProteinModelPortaliQ9LR65
SMRiQ9LR65
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 362PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST303

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
HOGENOMiHOG000233897
InParanoidiQ9LR65
OMAiFLWEEAF
OrthoDBiEOG09360CO1
PhylomeDBiQ9LR65

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 2 hits
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LR65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGCISKTSW SNEEPMHRPC LGMGCCGSKM GKRGFSDRMV SLHNLVSIPN
60 70 80 90 100
RIIGNGKSRS SCIFTQQGRK GINQDAMIVW EDFMSKDVTF CGVFDGHGPH
110 120 130 140 150
GHLVARKVRD SLPVKLLSLL NSIKSKQNGP IGTRASKSDS LEAEKEESTE
160 170 180 190 200
EDKLNFLWEE AFLKSFNAMD KELRSHPNLE CFCSGCTAVT IIKQGSNLYM
210 220 230 240 250
GNIGDSRAIL GSKDSNDSMI AVQLTVDLKP DLPREAERIK QCKGRVFALQ
260 270 280 290 300
DEPEVSRVWL PFDNAPGLAM ARAFGDFCLK DYGVISIPEF SHRVLTDRDQ
310 320 330 340 350
FIVLASDGVW DVLSNEEVVE VVASATSRAS AARLVVDSAV REWKLKYPTS
360 370 380 390 400
KMDDCAVVCL FLDGRMDSET SDNEEQCFSS ATNAVESDES QGAEPCLQRN
410 420 430 440 450
VTVRSLSTDQ ENNSYGKVIA EADNAEKEKT REGEQNWSGL EGVTRVNSLV
460
QLPRFPGEEP KT
Length:462
Mass (Da):50,975
Last modified:October 1, 2000 - v1
Checksum:iF264E7DA32C7E472
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002560 Genomic DNA Translation: AAF86530.1
CP002684 Genomic DNA Translation: AEE27587.1
AB079670 mRNA Translation: BAB84699.1
PIRiT00901
RefSeqiNP_171856.4, NM_100239.8
UniGeneiAt.42536
At.44796

Genome annotation databases

EnsemblPlantsiAT1G03590.1; AT1G03590.1; AT1G03590
GeneIDi839447
GrameneiAT1G03590.1; AT1G03590.1; AT1G03590
KEGGiath:AT1G03590

Similar proteinsi

Entry informationi

Entry nameiP2C01_ARATH
AccessioniPrimary (citable) accession number: Q9LR65
Secondary accession number(s): Q8SBC2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health