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Protein

Tryptophan aminotransferase-related protein 1

Gene

TAR1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probably involved in auxin production. TAA1, TAR1 and TAR2 are required for proper embryo patterning.1 Publication

Catalytic activityi

L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate.
L-tryptophan + pyruvate = indole-3-pyruvate + L-alanine.

Cofactori

Enzyme regulationi

Inhibited by L-kynurenine.1 Publication

Pathwayi: auxin biosynthesis

This protein is involved in the pathway auxin biosynthesis, which is part of Plant hormone metabolism.
View all proteins of this organism that are known to be involved in the pathway auxin biosynthesis and in Plant hormone metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei59Pyridoxal phosphateBy similarity1
Binding sitei169Pyridoxal phosphateBy similarity1
Binding sitei190Pyridoxal phosphateBy similarity1
Binding sitei224Pyridoxal phosphateBy similarity1

GO - Molecular functioni

  • carbon-sulfur lyase activity Source: InterPro
  • L-tryptophan:2-oxoglutarate aminotransferase activity Source: TAIR
  • L-tryptophan:pyruvate aminotransferase activity Source: TAIR

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase
Biological processAuxin biosynthesis
LigandPyridoxal phosphate

Enzyme and pathway databases

BRENDAi2.6.1.27 399
UniPathwayiUPA00151

Names & Taxonomyi

Protein namesi
Recommended name:
Tryptophan aminotransferase-related protein 1 (EC:2.6.1.27, EC:2.6.1.99)
Gene namesi
Name:TAR1
Ordered Locus Names:At1g23320
ORF Names:F26F24.17
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G23320
TAIRilocus:2028010 AT1G23320

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Disruption phenotypei

No visible phenotype.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004116741 – 388Tryptophan aminotransferase-related protein 1Add BLAST388

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei216N6-(pyridoxal phosphate)lysineSequence analysis1

Proteomic databases

PaxDbiQ9LR29

Expressioni

Tissue specificityi

Very low expression in seedlings.1 Publication

Inductioni

Slightly up-regulated by ethylene.1 Publication

Gene expression databases

ExpressionAtlasiQ9LR29 differential
GenevisibleiQ9LR29 AT

Interactioni

Protein-protein interaction databases

BioGridi24180, 1 interactor
STRINGi3702.AT1G23320.1

Structurei

3D structure databases

ProteinModelPortaliQ9LR29
SMRiQ9LR29
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni101 – 102Pyridoxal phosphate bindingBy similarity2
Regioni190 – 193Pyridoxal phosphate bindingBy similarity4
Regioni213 – 216Pyridoxal phosphate bindingBy similarity4

Sequence similaritiesi

Belongs to the alliinase family.Curated

Phylogenomic databases

eggNOGiENOG410II7N Eukaryota
ENOG41114NM LUCA
HOGENOMiHOG000237549
InParanoidiQ9LR29
KOiK16903
OMAiESVENCR
OrthoDBiEOG09360BJJ

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
InterProiView protein in InterPro
IPR006948 Alliinase_C
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF04864 Alliinase_C, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LR29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMVGCENSKK SDSGSNEDKS LSDDIINLDQ GDPTAFQEYW MKKKDRCTVV
60 70 80 90 100
IPAWDLMSYF SDTKNVCWFL EPELEKAIKA LHGAIGNAAT EERYIVVGTG
110 120 130 140 150
SSQLCQAALF ALSSLSEVKP VSIVAAVPYY STYVEEASYL QSTLYKWEGD
160 170 180 190 200
ARTFDKKGPY IELVTSPNNP DGIMREPVVN RREGGKVIHD LAYYWPHYTP
210 220 230 240 250
ITRRQDHDLM LFTFSKITGH AGSRIGWALV KDIEVAKKMV HYLTINSIGV
260 270 280 290 300
SKESQTRATT ILNELTKTCR TQSESFFEYG YEKMKSRWER LREVVESGDA
310 320 330 340 350
FTLPNYPQDF CNFFGKTLST SPAFAWLGYK EERDLGSLLK EKKVLTRGGD
360 370 380
RCGCNKRYVR VSMLSRDDDF DVSLQRLATI KDLKCVEP
Length:388
Mass (Da):44,064
Last modified:July 27, 2011 - v2
Checksum:i4B5FEA35566BBD12
GO

Sequence cautioni

The sequence AAF87014 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005292 Genomic DNA Translation: AAF87014.1 Different initiation.
CP002684 Genomic DNA Translation: AEE30372.1
RefSeqiNP_173746.1, NM_102181.1
UniGeneiAt.51734

Genome annotation databases

EnsemblPlantsiAT1G23320.1; AT1G23320.1; AT1G23320
GeneIDi838941
GrameneiAT1G23320.1; AT1G23320.1; AT1G23320
KEGGiath:AT1G23320

Similar proteinsi

Entry informationi

Entry nameiTAR1_ARATH
AccessioniPrimary (citable) accession number: Q9LR29
Secondary accession number(s): F4I655
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: July 27, 2011
Last modified: May 23, 2018
This is version 91 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

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