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Q9LQ95 (Y1164_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
BTB/POZ domain-containing protein At1g01640
Gene names
Ordered Locus Names:At1g01640
ORF Names:T1N6.2
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length207 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Pathway

Protein modification; protein ubiquitination.

Subunit structure

Interacts with CUL3A. Ref.6

Domain

The BTB/POZ-like domain may mediate the interaction with some component of ubiquitin ligase complexes. Ref.5

Sequence similarities

Contains 1 BTB (POZ) domain.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein ubiquitination

Inferred from electronic annotation. Source: UniProtKB-UniPathway

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 207207BTB/POZ domain-containing protein At1g01640
PRO_0000405996

Regions

Domain24 – 9471BTB

Experimental info

Sequence conflict791K → R in AAQ22660. Ref.3
Sequence conflict791K → R in BAF01519. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q9LQ95 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: A108E941AE9221F0

FASTA20723,372
        10         20         30         40         50         60 
MTEAEQKAAF LGGLVVSFKE QMHTDVLVKP GEEAPPIPTH KAVLAARSKV FRNMLDSDEC 

        70         80         90        100        110        120 
KTSPEESITL PDLSHDELKS LLEFLYSGNL KAPYNQYRSL YLAADKYDIS YLQDVCRNHF 

       130        140        150        160        170        180 
IASLSSRNVL DILELASIPC DTILKDAAIN HIVKHMEEVV VPMKYETFVQ RNPDLSVEIT 

       190        200 
RAYLRETKAK AKDHGAPLNG NTRPRIW 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Cullins 3a and 3b assemble with members of the broad complex/tramtrack/bric-a-brac (BTB) protein family to form essential ubiquitin-protein ligases (E3s) in Arabidopsis."
Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L., Vierstra R.D.
J. Biol. Chem. 280:18810-18821(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: DOMAIN BTB.
[6]"Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo."
Figueroa P., Gusmaroli G., Serino G., Habashi J., Ma L., Shen Y., Feng S., Bostick M., Callis J., Hellmann H., Deng X.W.
Plant Cell 17:1180-1195(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH CUL3A.

Web resources

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC009273 Genomic DNA. Translation: AAF78396.1.
CP002684 Genomic DNA. Translation: AEE27315.1.
CP002684 Genomic DNA. Translation: AEE27316.1.
BT010191 mRNA. Translation: AAQ22660.1.
AK229678 mRNA. Translation: BAF01519.1.
PIRC86147.
RefSeqNP_171670.1. NM_100046.3.
NP_849574.1. NM_179243.3.
UniGeneAt.14892.

3D structure databases

ProteinModelPortalQ9LQ95.
SMRQ9LQ95. Positions 7-185.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid24769. 3 interactions.
IntActQ9LQ95. 3 interactions.
STRING3702.AT1G01640.1-P.

Proteomic databases

PaxDbQ9LQ95.
PRIDEQ9LQ95.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G01640.1; AT1G01640.1; AT1G01640.
AT1G01640.2; AT1G01640.2; AT1G01640.
GeneID839534.
KEGGath:AT1G01640.

Organism-specific databases

TAIRAT1G01640.

Phylogenomic databases

eggNOGNOG321590.
HOGENOMHOG000029690.
InParanoidQ9LQ95.
KOK10523.
OMAAINHIVK.
PhylomeDBQ9LQ95.
ProtClustDBCLSN2682872.

Enzyme and pathway databases

UniPathwayUPA00143.

Gene expression databases

GenevestigatorQ9LQ95.

Family and domain databases

Gene3D3.30.710.10. 1 hit.
InterProIPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR013069. BTB_POZ.
[Graphical view]
PfamPF00651. BTB. 1 hit.
[Graphical view]
SMARTSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMSSF54695. SSF54695. 1 hit.
PROSITEPS50097. BTB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY1164_ARATH
AccessionPrimary (citable) accession number: Q9LQ95
Secondary accession number(s): Q7XA69
Entry history
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: October 1, 2000
Last modified: March 19, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names