Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9LQ95

- Y1164_ARATH

UniProt

Q9LQ95 - Y1164_ARATH

Protein

BTB/POZ domain-containing protein At1g01640

Gene

At1g01640

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

    Pathwayi

    GO - Molecular functioni

    1. protein binding Source: TAIR

    GO - Biological processi

    1. protein ubiquitination Source: UniProtKB-UniPathway

    Keywords - Biological processi

    Ubl conjugation pathway

    Enzyme and pathway databases

    UniPathwayiUPA00143.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    BTB/POZ domain-containing protein At1g01640
    Gene namesi
    Ordered Locus Names:At1g01640
    ORF Names:T1N6.2
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G01640.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 207207BTB/POZ domain-containing protein At1g01640PRO_0000405996Add
    BLAST

    Proteomic databases

    PaxDbiQ9LQ95.
    PRIDEiQ9LQ95.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9LQ95.

    Interactioni

    Subunit structurei

    Interacts with CUL3A.1 Publication

    Protein-protein interaction databases

    BioGridi24769. 3 interactions.
    IntActiQ9LQ95. 3 interactions.
    STRINGi3702.AT1G01640.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9LQ95.
    SMRiQ9LQ95. Positions 11-182.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini24 – 9471BTBPROSITE-ProRule annotationAdd
    BLAST

    Domaini

    The BTB/POZ-like domain may mediate the interaction with some component of ubiquitin ligase complexes.1 Publication

    Sequence similaritiesi

    Contains 1 BTB (POZ) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG321590.
    HOGENOMiHOG000029690.
    InParanoidiQ9LQ95.
    KOiK10523.
    OMAiAINHIVK.
    PhylomeDBiQ9LQ95.

    Family and domain databases

    Gene3Di3.30.710.10. 1 hit.
    InterProiIPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR013069. BTB_POZ.
    [Graphical view]
    PfamiPF00651. BTB. 1 hit.
    [Graphical view]
    SMARTiSM00225. BTB. 1 hit.
    [Graphical view]
    SUPFAMiSSF54695. SSF54695. 1 hit.
    PROSITEiPS50097. BTB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9LQ95-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTEAEQKAAF LGGLVVSFKE QMHTDVLVKP GEEAPPIPTH KAVLAARSKV    50
    FRNMLDSDEC KTSPEESITL PDLSHDELKS LLEFLYSGNL KAPYNQYRSL 100
    YLAADKYDIS YLQDVCRNHF IASLSSRNVL DILELASIPC DTILKDAAIN 150
    HIVKHMEEVV VPMKYETFVQ RNPDLSVEIT RAYLRETKAK AKDHGAPLNG 200
    NTRPRIW 207
    Length:207
    Mass (Da):23,372
    Last modified:October 1, 2000 - v1
    Checksum:iA108E941AE9221F0
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti79 – 791K → R in AAQ22660. (PubMed:14593172)Curated
    Sequence conflicti79 – 791K → R in BAF01519. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC009273 Genomic DNA. Translation: AAF78396.1.
    CP002684 Genomic DNA. Translation: AEE27315.1.
    CP002684 Genomic DNA. Translation: AEE27316.1.
    BT010191 mRNA. Translation: AAQ22660.1.
    AK229678 mRNA. Translation: BAF01519.1.
    PIRiC86147.
    RefSeqiNP_171670.1. NM_100046.3.
    NP_849574.1. NM_179243.3.
    UniGeneiAt.14892.

    Genome annotation databases

    EnsemblPlantsiAT1G01640.1; AT1G01640.1; AT1G01640.
    AT1G01640.2; AT1G01640.2; AT1G01640.
    GeneIDi839534.
    KEGGiath:AT1G01640.

    Cross-referencesi

    Web resourcesi

    PlantsUBQ

    A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC009273 Genomic DNA. Translation: AAF78396.1 .
    CP002684 Genomic DNA. Translation: AEE27315.1 .
    CP002684 Genomic DNA. Translation: AEE27316.1 .
    BT010191 mRNA. Translation: AAQ22660.1 .
    AK229678 mRNA. Translation: BAF01519.1 .
    PIRi C86147.
    RefSeqi NP_171670.1. NM_100046.3.
    NP_849574.1. NM_179243.3.
    UniGenei At.14892.

    3D structure databases

    ProteinModelPortali Q9LQ95.
    SMRi Q9LQ95. Positions 11-182.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 24769. 3 interactions.
    IntActi Q9LQ95. 3 interactions.
    STRINGi 3702.AT1G01640.1-P.

    Proteomic databases

    PaxDbi Q9LQ95.
    PRIDEi Q9LQ95.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G01640.1 ; AT1G01640.1 ; AT1G01640 .
    AT1G01640.2 ; AT1G01640.2 ; AT1G01640 .
    GeneIDi 839534.
    KEGGi ath:AT1G01640.

    Organism-specific databases

    TAIRi AT1G01640.

    Phylogenomic databases

    eggNOGi NOG321590.
    HOGENOMi HOG000029690.
    InParanoidi Q9LQ95.
    KOi K10523.
    OMAi AINHIVK.
    PhylomeDBi Q9LQ95.

    Enzyme and pathway databases

    UniPathwayi UPA00143 .

    Gene expression databases

    Genevestigatori Q9LQ95.

    Family and domain databases

    Gene3Di 3.30.710.10. 1 hit.
    InterProi IPR000210. BTB/POZ-like.
    IPR011333. BTB/POZ_fold.
    IPR013069. BTB_POZ.
    [Graphical view ]
    Pfami PF00651. BTB. 1 hit.
    [Graphical view ]
    SMARTi SM00225. BTB. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54695. SSF54695. 1 hit.
    PROSITEi PS50097. BTB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
      Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
      , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
      Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Cullins 3a and 3b assemble with members of the broad complex/tramtrack/bric-a-brac (BTB) protein family to form essential ubiquitin-protein ligases (E3s) in Arabidopsis."
      Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L., Vierstra R.D.
      J. Biol. Chem. 280:18810-18821(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: DOMAIN BTB.
    6. "Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo."
      Figueroa P., Gusmaroli G., Serino G., Habashi J., Ma L., Shen Y., Feng S., Bostick M., Callis J., Hellmann H., Deng X.W.
      Plant Cell 17:1180-1195(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH CUL3A.

    Entry informationi

    Entry nameiY1164_ARATH
    AccessioniPrimary (citable) accession number: Q9LQ95
    Secondary accession number(s): Q7XA69
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 8, 2011
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3