Reviewed, UniProtKB/Swiss-Prot Q9LQ73 (PX11C_ARATH)

Names and origin

Protein names

Recommended name:
    Peroxisomal membrane protein 11C
Alternative name(s):
    Peroxin-11C
      Short name=AtPEX11c

Gene names

Name:	PEX11C
Synonyms:	PEX11-1
Ordered Locus Names:	At1g01820
ORF Names:	T1N6.24

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	235 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Involved in peroxisomal proliferation. Promotes peroxisomal duplication, aggregation or elongation without fission. Ref.6 Ref.7
Subcellular location	Peroxisome membrane; Multi-pass membrane protein Ref.7.
Tissue specificity	Expressed in roots and developing siliques. Ref.6 Ref.7
Induction	Up-regulated during senescence. Ref.7
Miscellaneous	Can complement the yeast pex11 null mutant.
Sequence similarities	Belongs to the peroxin-11 family.

Ontologies

Keywords
Biological process	Peroxisome biogenesis
Cellular component	Membrane Peroxisome
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	peroxisome fission Ref.7 Inferred from mutant phenotype. Source: TAIR
Cellular component	integral to peroxisomal membrane Ref.7 Inferred from direct assay. Source: TAIR
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 235	235	Peroxisomal membrane protein 11C		PRO_0000330297
Regions
	Topological domain	1 – 91	91	Cytoplasmic Ref.6
	Transmembrane	92 – 108	17	Potential
	Topological domain	109 – 206	98	Lumenal Ref.6
	Transmembrane	207 – 226	20	Potential
	Topological domain	227 – 235	9	Cytoplasmic Ref.6
Experimental info
	Sequence conflict	124	1	R → L in CAD58675. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q9LQ73-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 8DE9422A23181A49	FASTA	235	25,912
	10 20 30 40 50 60 MSTLETTRAE LGLVVVYLNK AEARDKICRA IQYGSKFLSD GQPGTAQNVD KNTSLARKVF 70 80 90 100 110 120 RLFKFVNDLH ALISPVPKGT PLPLVLLGKS KNALLSTFLF LDQIVWLGRT GIYKDKERAE 130 140 150 160 170 180 ILGRISLFCW MGSSVCTSLV EVGELGRLSA SIKKLEKEIG NKDKHQNEQY RAKVEKSNER 190 200 210 220 230 SLALIKAGMD VVVAFGLLQL APKKVTPRVT GAFGFASSLI SCYQLLPSHP KSKMV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Pex 11 homologue." Yamaguchi K., Nishimura M. Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia.
[2]	"AtPEX11 and peroxisome proliferation in Arabidopsis thaliana." El Shami M., Baker A. Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Seedling.
[3]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[4]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[5]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[6]	"Five Arabidopsis peroxin 11 homologs individually promote peroxisome elongation, duplication or aggregation." Lingard M.J., Trelease R.N. J. Cell Sci. 119:1961-1972(2006) [PubMed: 16636080] [Abstract] Cited for: FUNCTION, TOPOLOGY, TISSUE SPECIFICITY, NOMENCLATURE.
[7]	"The PEROXIN11 protein family controls peroxisome proliferation in Arabidopsis." Orth T., Reumann S., Zhang X., Fan J., Wenzel D., Quan S., Hu J. Plant Cell 19:333-350(2007) [PubMed: 17220199] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION, GENE FAMILY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB022861 mRNA. Translation: BAD83578.1. AJ520104 mRNA. Translation: CAD58675.1. AC009273 Genomic DNA. Translation: AAF78415.1. AF332441 mRNA. Translation: AAG48804.1. AY064139 mRNA. Translation: AAL36046.1. AY097406 mRNA. Translation: AAM19922.1. AY086844 mRNA. Translation: AAM63892.1.
IPI	IPI00532575.
PIR	A86150.
RefSeq	NP_563636.1.
UniGene	At.24237
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9LQ73.
Proteomic databases
PRIDE	Q9LQ73.
Genome annotation databases
GeneID	839257.
GenomeReviews	Gene locus AT1G01820 in contig CT485782_GR.
KEGG	ath:AT1G01820.
NMPDR	fig|3702.1.peg.294.
Organism-specific databases
TAIR	At1g01820.
Phylogenomic databases
HOGENOM	HBG318175.
InParanoid	Q9LQ73.
OMA	WLGRTGI.
Gene expression databases
ArrayExpress	Q9LQ73.
Genevestigator	Q9LQ73.
Family and domain databases
InterPro	IPR008733. PEX11. [Graphical view]
PANTHER	PTHR12652. PEX11. 1 hit.
Pfam	PF05648. PEX11. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PX11C_ARATH

Accession

Primary (citable) accession number: Q9LQ73
Secondary accession number(s): Q5QT12

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 29, 2008
Last sequence update:	October 1, 2000
Last modified:	December 15, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)