Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9LQ48 (GSTUF_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase U15

Short name=AtGSTU15
EC=2.5.1.18
Alternative name(s):
GST class-tau member 15
Gene names
Name:GSTU15
Ordered Locus Names:At1g59670
ORF Names:T30E16.25
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides By similarity.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subcellular location

Cytoplasmcytosol Probable.

Sequence similarities

Belongs to the GST superfamily. Tau family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Sequence caution

The sequence ABK28444.1 differs from that shown. Reason: Erroneous termination at position 234. Translated as stop.

Ontologies

Keywords
   Biological processDetoxification
   Cellular componentCytoplasm
   Molecular functionTransferase
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processresponse to toxic substance

Inferred from electronic annotation. Source: UniProtKB-KW

toxin catabolic process

Traceable author statement Ref.5. Source: TAIR

   Cellular_componentcytoplasm

Non-traceable author statement Ref.5. Source: TAIR

cytosol

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 233233Glutathione S-transferase U15
PRO_0000413561

Regions

Domain5 – 8581GST N-terminal
Domain92 – 219128GST C-terminal
Region15 – 162Glutathione binding By similarity
Region42 – 432Glutathione binding By similarity
Region56 – 572Glutathione binding By similarity
Region69 – 702Glutathione binding By similarity

Amino acid modifications

Modified residue1581Phosphothreonine By similarity

Experimental info

Sequence conflict61E → Q in AAM61551. Ref.4
Sequence conflict241A → D in AAM61551. Ref.4
Sequence conflict381D → N in AAM61551. Ref.4
Sequence conflict53 – 542IF → VY in AAM61551. Ref.4
Sequence conflict1411E → D in AAM61551. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q9LQ48 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 8722CA2CE7AEC09D

FASTA23326,535
        10         20         30         40         50         60 
MGEREEVKLL GTWYSPVVIR AKIALRLKSV DYDYVEEDLF GSKSELLLKS NPIFKKVPVL 

        70         80         90        100        110        120 
IHNTKPVCVS LNIVEYIDET WNSSGSSILP SHPYDRALAR FWSVFVDDKW LPTLMAAVVA 

       130        140        150        160        170        180 
KSEEAKAKGM EEVEEGLLQL EAAFIALSKG KSFFGGETIG FIDICLGSFL VLLKAREKLK 

       190        200        210        220        230 
NEKILDELKT PSLYRWANQF LSNEMVKNVV PDIDKVAKFI EEFEDRAQYI RCF 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations."
Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.
Plant Biotechnol. J. 4:317-324(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]"Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
Wagner U., Edwards R., Dixon D.P., Mauch F.
Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC009317 Genomic DNA. Translation: AAF79758.1.
CP002684 Genomic DNA. Translation: AEE33601.1.
DQ446376 mRNA. Translation: ABE65725.1.
DQ652904 mRNA. Translation: ABK28444.1. Sequence problems.
AY084992 mRNA. Translation: AAM61551.1.
PIRD96620.
RefSeqNP_176176.1. NM_104660.2.
UniGeneAt.36811.

3D structure databases

ProteinModelPortalQ9LQ48.
SMRQ9LQ48. Positions 5-224.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT1G59670.1-P.

Proteomic databases

PRIDEQ9LQ48.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G59670.1; AT1G59670.1; AT1G59670.
GeneID842257.
KEGGath:AT1G59670.

Organism-specific databases

TAIRAT1G59670.

Phylogenomic databases

eggNOGNOG287605.
HOGENOMHOG000125749.
InParanoidQ9LQ48.
KOK00799.
OMAMAIWVEE.
PhylomeDBQ9LQ48.
ProtClustDBCLSN2679688.

Enzyme and pathway databases

BioCycARA:AT1G59670-MONOMER.

Gene expression databases

GenevestigatorQ9LQ48.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTUF_ARATH
AccessionPrimary (citable) accession number: Q9LQ48
Secondary accession number(s): A0MED4, Q8LF83
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: October 1, 2000
Last modified: March 19, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names