Q9LNJ5 (BH013_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transcription factor bHLH13

Alternative name(s):
Basic helix-loop-helix protein 13
Short name=AtbHLH13
Short name=bHLH 13
Transcription factor EN 39
bHLH transcription factor bHLH013

Gene names

Name:	BHLH13
Synonyms:	EN39
Ordered Locus Names:	At1g01260
ORF Names:	F6F3.7

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	590 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subunit structure	Homodimer Probable.
Subcellular location	Nucleus Potential.
Induction	By UV treatment. Ref.1
Sequence similarities	Contains 1 basic helix-loop-helix (bHLH) domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Ligand	DNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Traceable author statement. Source: TAIR transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 590	590	Transcription factor bHLH13		PRO_0000358730
Regions
	Domain	443 – 483	41	Helix-loop-helix motif
	DNA binding	426 – 442	17	Basic motif By similarity
	Compositional bias	275 – 295	21	Gln-rich
Experimental info
	Sequence conflict	134	1	E → K in AAM10932. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q9LNJ5 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 0BCCF4DB5593D95E	FASTA	590	66,002
	10 20 30 40 50 60 MNIGRLVWNE DDKAIVASLL GKRALDYLLS NSVSNANLLM TLGSDENLQN KLSDLVERPN 70 80 90 100 110 120 ASNFSWNYAI FWQISRSKAG DLVLCWGDGY CREPKEGEKS EIVRILSMGR EEETHQTMRK 130 140 150 160 170 180 RVLQKLHDLF GGSEEENCAL GLDRVTDTEM FLLSSMYFSF PRGEGGPGKC FASAKPVWLS 190 200 210 220 230 240 DVVNSGSDYC VRSFLAKSAG IQTVVLVPTD LGVVELGSTS CLPESEDSIL SIRSLFTSSL 250 260 270 280 290 300 PPVRAVALPV TVAEKIDDNR TKIFGKDLHN SGFLQHHQHH QQQQQQPPQQ QQHRQFREKL 310 320 330 340 350 360 TVRKMDDRAP KRLDAYPNNG NRFMFSNPGT NNNTLLSPTW VQPENYTRPI NVKEVPSTDE 370 380 390 400 410 420 FKFLPLQQSS QRLLPPAQMQ IDFSAASSRA SENNSDGEGG GEWADAVGAD ESGNNRPRKR 430 440 450 460 470 480 GRRPANGRAE ALNHVEAERQ RREKLNQRFY ALRSVVPNIS KMDKASLLGD AVSYINELHA 490 500 510 520 530 540 KLKVMEAERE RLGYSSNPPI SLDSDINVQT SGEDVTVRIN CPLESHPASR IFHAFEESKV 550 560 570 580 590 EVINSNLEVS QDTVLHTFVV KSEELTKEKL ISALSREQTN SVQSRTSSGR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity." Heim M.A., Jakoby M., Werber M., Martin C., Weisshaar B., Bailey P.C. Mol. Biol. Evol. 20:735-747(2003) [PubMed: 12679534] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], INDUCTION BY UV LIGHT, GENE FAMILY, NOMENCLATURE. Strain: cv. Columbia. Tissue: Root.
[2]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[4]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[5]	"The Arabidopsis basic/helix-loop-helix transcription factor family." Toledo-Ortiz G., Huq E., Quail P.H. Plant Cell 15:1749-1770(2003) [PubMed: 12897250] [Abstract] Cited for: GENE FAMILY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF251698 mRNA. Translation: AAL55720.1. AC023628 Genomic DNA. Translation: AAF97322.1. CP002684 Genomic DNA. Translation: AEE27262.1. CP002684 Genomic DNA. Translation: AEE27263.1. CP002684 Genomic DNA. Translation: AEE27264.1. AF488559 mRNA. Translation: AAM10932.1. AY079012 mRNA. Translation: AAL84968.1. AY120752 mRNA. Translation: AAM53310.1. BT004517 mRNA. Translation: AAO42763.1.
IPI	IPI00539052.
PIR	H86142.
RefSeq	NP_001077440.1. NM_001083971.1. NP_001184883.1. NM_001197954.1. NP_171634.1. NM_100009.2.
UniGene	At.28312.
3D structure databases
ProteinModelPortal	Q9LNJ5.
SMR	Q9LNJ5. Positions 433-483.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9LNJ5. 5 interactions.
Proteomic databases
PRIDE	Q9LNJ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G01260.1; AT1G01260.1; AT1G01260. AT1G01260.2; AT1G01260.2; AT1G01260. AT1G01260.3; AT1G01260.3; AT1G01260.
GeneID	839545.
GenomeReviews	Gene locus AT1G01260 in contig CT485782_GR.
KEGG	ath:AT1G01260.
NMPDR	fig|3702.1.peg.236.
Organism-specific databases
TAIR	At1g01260.
Phylogenomic databases
GeneTree	EPGT00070000028117.
HOGENOM	HBG596393.
InParanoid	Q9LNJ5.
OMA	QMQIDFS.
PhylomeDB	Q9LNJ5.
ProtClustDB	CLSN2682849.
Gene expression databases
ArrayExpress	Q9LNJ5.
Genevestigator	Q9LNJ5.
Family and domain databases
InterPro	IPR011598. HLH_DNA-bd. [Graphical view]
Gene3D	G3DSA:4.10.280.10. HLH_DNA_bd. 1 hit.
Pfam	PF00010. HLH. 1 hit. [Graphical view]
SMART	SM00353. HLH. 1 hit. [Graphical view]
SUPFAM	SSF47459. HLH_basic. 1 hit.
PROSITE	PS50888. HLH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BH013_ARATH

Accession

Primary (citable) accession number: Q9LNJ5
Secondary accession number(s): Q8S3F5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 16, 2008
Last sequence update:	October 1, 2000
Last modified:	December 14, 2011
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program