Q9LNF4 (P2C13_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 13
Short name=AtPP2C13
EC=3.1.3.16

Gene names

Ordered Locus Names:	At1g48040
ORF Names:	F21D18.27, T2J15.5

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	383 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.
Sequence caution	The sequence AAF79528.1 differs from that shown. Reason: Erroneous initiation. The sequence AAG51521.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein dephosphorylation Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 383	383	Probable protein phosphatase 2C 13		PRO_0000367944
Regions
	Domain	77 – 342	266	PP2C-like
Sites
	Metal binding	121	1	Manganese 1 By similarity
	Metal binding	121	1	Manganese 2 By similarity
	Metal binding	122	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	297	1	Manganese 2 By similarity
	Metal binding	340	1	Manganese 2 By similarity
Experimental info
	Sequence conflict	160	1	E → G in BAD44439. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q9LNF4 [UniParc]. Last modified April 14, 2009. Version 2. Checksum: 4304B1895B801ECF	FASTA	383	42,106
	10 20 30 40 50 60 MILSQTMVAE AEIRVLDVKC HISAPKDQKN FQIDEVRVSE SVRAEISGSA ETPRFGSGMS 70 80 90 100 110 120 CVTTTIGESA SDFIPTIRSG SFADIRSRET MEDEHICIDD LSAHLGSYNF SVPSAFYGVF 130 140 150 160 170 180 DGHGGPEAAI FMKENLTRLF FQDAVFPEMP SIVDAFFLEE LENSHRKAFA LADLAMADET 190 200 210 220 230 240 IVSGSCGTTA LTALIIGRHL LVANAGDCRA VLCRRGVAVD MSFDHRSTYE PERRRIEDLG 250 260 270 280 290 300 GYFEDGYLNG VLAVTRAIGD WELKNPFTDS SSPLISDPEI GQIILTEDDE FLILACDGIW 310 320 330 340 350 360 DVLSSQNAVS NVRQGLRRHG DPRQCAMELG KEAARLQSSD NMTVIVICFS SVPSSPKQPQ 370 380 RRRLRFCVSD EARARLQAML AGE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs." Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K. Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Arabidopsis ORF clones." Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R. Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-383. Strain: cv. Columbia.
[5]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC023673 Genomic DNA. Translation: AAF79528.1. Different initiation. AC051631 Genomic DNA. Translation: AAG51521.1. Different initiation. CP002684 Genomic DNA. Translation: AEE32241.1. AK176010 mRNA. Translation: BAD43773.1. AK176676 mRNA. Translation: BAD44439.1. BT015400 mRNA. Translation: AAU05523.1.
IPI	IPI00519067.
RefSeq	NP_175238.2. NM_103700.3.
UniGene	At.38490.
3D structure databases
HSSP	HSSP built from PDB template 1A6Q based on UniProtKB P35813.
ProteinModelPortal	Q9LNF4.
SMR	Q9LNF4. Positions 65-349.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G48040.1; AT1G48040.1; AT1G48040.
GeneID	841222.
KEGG	ath:AT1G48040.
Organism-specific databases
TAIR	At1g48040.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233896.
InParanoid	Q67XZ2.
KO	K14803.
OMA	CARELAM.
PhylomeDB	Q9LNF4.
ProtClustDB	CLSN2690996.
Gene expression databases
Genevestigator	Q9LNF4.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR000222. PP2C_Mn2_Asp60_BS. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C13_ARATH

Accession

Primary (citable) accession number: Q9LNF4
Secondary accession number(s): Q67XZ2, Q67ZV7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 14, 2009
Last modified:	May 1, 2013
This is version 73 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program