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Q9LNF4

- P2C13_ARATH

UniProt

Q9LNF4 - P2C13_ARATH

Protein

Probable protein phosphatase 2C 13

Gene

At1g48040

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 2 (14 Apr 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi121 – 1211Manganese 1By similarity
    Metal bindingi121 – 1211Manganese 2By similarity
    Metal bindingi122 – 1221Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi297 – 2971Manganese 2By similarity
    Metal bindingi340 – 3401Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT1G48040-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 13 (EC:3.1.3.16)
    Short name:
    AtPP2C13
    Gene namesi
    Ordered Locus Names:At1g48040
    ORF Names:F21D18.27, T2J15.5
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G48040.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 383383Probable protein phosphatase 2C 13PRO_0000367944Add
    BLAST

    Proteomic databases

    PRIDEiQ9LNF4.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9LNF4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9LNF4.
    SMRiQ9LNF4. Positions 65-349.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini77 – 342266PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233896.
    InParanoidiQ67XZ2.
    KOiK14803.
    OMAiTECGGYI.
    PhylomeDBiQ9LNF4.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9LNF4-1 [UniParc]FASTAAdd to Basket

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    MILSQTMVAE AEIRVLDVKC HISAPKDQKN FQIDEVRVSE SVRAEISGSA    50
    ETPRFGSGMS CVTTTIGESA SDFIPTIRSG SFADIRSRET MEDEHICIDD 100
    LSAHLGSYNF SVPSAFYGVF DGHGGPEAAI FMKENLTRLF FQDAVFPEMP 150
    SIVDAFFLEE LENSHRKAFA LADLAMADET IVSGSCGTTA LTALIIGRHL 200
    LVANAGDCRA VLCRRGVAVD MSFDHRSTYE PERRRIEDLG GYFEDGYLNG 250
    VLAVTRAIGD WELKNPFTDS SSPLISDPEI GQIILTEDDE FLILACDGIW 300
    DVLSSQNAVS NVRQGLRRHG DPRQCAMELG KEAARLQSSD NMTVIVICFS 350
    SVPSSPKQPQ RRRLRFCVSD EARARLQAML AGE 383
    Length:383
    Mass (Da):42,106
    Last modified:April 14, 2009 - v2
    Checksum:i4304B1895B801ECF
    GO

    Sequence cautioni

    The sequence AAF79528.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAG51521.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti160 – 1601E → G in BAD44439. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC023673 Genomic DNA. Translation: AAF79528.1. Different initiation.
    AC051631 Genomic DNA. Translation: AAG51521.1. Different initiation.
    CP002684 Genomic DNA. Translation: AEE32241.1.
    AK176010 mRNA. Translation: BAD43773.1.
    AK176676 mRNA. Translation: BAD44439.1.
    BT015400 mRNA. Translation: AAU05523.1.
    RefSeqiNP_175238.2. NM_103700.3.
    UniGeneiAt.38490.

    Genome annotation databases

    EnsemblPlantsiAT1G48040.1; AT1G48040.1; AT1G48040.
    GeneIDi841222.
    KEGGiath:AT1G48040.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC023673 Genomic DNA. Translation: AAF79528.1 . Different initiation.
    AC051631 Genomic DNA. Translation: AAG51521.1 . Different initiation.
    CP002684 Genomic DNA. Translation: AEE32241.1 .
    AK176010 mRNA. Translation: BAD43773.1 .
    AK176676 mRNA. Translation: BAD44439.1 .
    BT015400 mRNA. Translation: AAU05523.1 .
    RefSeqi NP_175238.2. NM_103700.3.
    UniGenei At.38490.

    3D structure databases

    ProteinModelPortali Q9LNF4.
    SMRi Q9LNF4. Positions 65-349.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q9LNF4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G48040.1 ; AT1G48040.1 ; AT1G48040 .
    GeneIDi 841222.
    KEGGi ath:AT1G48040.

    Organism-specific databases

    TAIRi AT1G48040.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233896.
    InParanoidi Q67XZ2.
    KOi K14803.
    OMAi TECGGYI.
    PhylomeDBi Q9LNF4.

    Enzyme and pathway databases

    BioCyci ARA:AT1G48040-MONOMER.

    Gene expression databases

    Genevestigatori Q9LNF4.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
      Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
      , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
      Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Arabidopsis ORF clones."
      Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.
      Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-383.
      Strain: cv. Columbia.
    5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C13_ARATH
    AccessioniPrimary (citable) accession number: Q9LNF4
    Secondary accession number(s): Q67XZ2, Q67ZV7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: April 14, 2009
    Last modified: October 1, 2014
    This is version 83 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3