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Protein

Probable 6-phosphogluconolactonase 1

Gene

At1g13700

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.By similarity

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage).
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Glucose-6-phosphate 1-dehydrogenase 3, chloroplastic (At1g24280), Glucose-6-phosphate 1-dehydrogenase 1, chloroplastic (APG1), Glucose-6-phosphate 1-dehydrogenase (At3g27300), Glucose-6-phosphate 1-dehydrogenase (AXX17_At3g29760), Glucose-6-phosphate 1-dehydrogenase (G6PD4), Glucose-6-phosphate 1-dehydrogenase 2, chloroplastic (At5g13110), Glucose-6-phosphate 1-dehydrogenase (AXX17_At1g25530), Glucose-6-phosphate 1-dehydrogenase (At5g35790), Glucose-6-phosphate 1-dehydrogenase (AXX17_At5g33080), Glucose-6-phosphate 1-dehydrogenase (AXX17_At5g33080), Glucose-6-phosphate 1-dehydrogenase (AXX17_At5g12520), Glucose-6-phosphate 1-dehydrogenase (G6PD5), Glucose-6-phosphate 1-dehydrogenase (G6PD5), Glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform 2 (ACG12), Glucose-6-phosphate 1-dehydrogenase (At1g09420), Glucose-6-phosphate 1-dehydrogenase (AXX17_At5g38480), Glucose-6-phosphate 1-dehydrogenase (AXX17_At1g09330), Glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform 1 (ACG9), Glucose-6-phosphate 1-dehydrogenase (At5g40760), Glucose-6-phosphate 1-dehydrogenase 4, chloroplastic (At1g09420)
  2. Probable 6-phosphogluconolactonase 5, chloroplastic (EMB2024), Probable 6-phosphogluconolactonase 3 (At5g24420), Probable 6-phosphogluconolactonase 4 (At5g24410), Probable 6-phosphogluconolactonase 1 (At1g13700), Probable 6-phosphogluconolactonase 2 (At3g49360)
  3. 6-phosphogluconate dehydrogenase, decarboxylating (AXX17_At5g39410), 6-phosphogluconate dehydrogenase, decarboxylating (AXX17_At3g01580), 6-phosphogluconate dehydrogenase, decarboxylating 2, chloroplastic (At5g41670), 6-phosphogluconate dehydrogenase, decarboxylating 3 (At3g02360), 6-phosphogluconate dehydrogenase, decarboxylating 1, chloroplastic (At1g64190), 6-phosphogluconate dehydrogenase, decarboxylating (AXX17_At1g57660)
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciARA:AT1G13700-MONOMER
BRENDAi3.1.1.31 399
ReactomeiR-ATH-71336 Pentose phosphate pathway (hexose monophosphate shunt)
UniPathwayiUPA00115; UER00409

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 6-phosphogluconolactonase 1 (EC:3.1.1.31)
Short name:
6PGL 1
Gene namesi
Ordered Locus Names:At1g13700
ORF Names:F21F23.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G13700
TAIRilocus:2023842 AT1G13700

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002886681 – 268Probable 6-phosphogluconolactonase 1Add BLAST268

Proteomic databases

PaxDbiQ9LMX8
PRIDEiQ9LMX8

Expressioni

Gene expression databases

ExpressionAtlasiQ9LMX8 baseline and differential
GenevisibleiQ9LMX8 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G13700.1

Structurei

3D structure databases

ProteinModelPortaliQ9LMX8
SMRiQ9LMX8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3147 Eukaryota
COG0363 LUCA
HOGENOMiHOG000256285
InParanoidiQ9LMX8
KOiK01057
OMAiEMEGYQY
OrthoDBiEOG09360J6V
PhylomeDBiQ9LMX8

Family and domain databases

CDDicd01400 6PGL, 1 hit
InterProiView protein in InterPro
IPR005900 6-phosphogluconolactonase_DevB
IPR006148 Glc/Gal-6P_isomerase
IPR037171 NagB/RpiA_transferase-like
PfamiView protein in Pfam
PF01182 Glucosamine_iso, 1 hit
SUPFAMiSSF100950 SSF100950, 1 hit
TIGRFAMsiTIGR01198 pgl, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LMX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALTWTHKDR GEIRVHENLE ELSIDLVDYI AEISEASIKE HGAFCIVLSG
60 70 80 90 100
GSLISFMGKL IEPPYDKIVD WAKWYVFWAD ERVVAKNHDD SNYKLAKDNL
110 120 130 140 150
LSKVNVFPRH ICSINDTVSA EEAATEYEFA IRQMVRSRTV AASDNSDSPR
160 170 180 190 200
FDLILLGMGS DGHVASLFPN HPALEVKDDW VTFLTDSHKP PPERITFTLP
210 220 230 240 250
VINSAANVVV VATGESKANA IHLAIDDLPL PDSSLSLPAR LVHPSNGNLI
260
WFMDKQAGSK LDRFKFSE
Length:268
Mass (Da):29,887
Last modified:October 1, 2000 - v1
Checksum:iBF11D4FAC1E81294
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC027656 Genomic DNA Translation: AAF81297.1
CP002684 Genomic DNA Translation: AEE29059.1
CP002684 Genomic DNA Translation: ANM59247.1
CP002684 Genomic DNA Translation: ANM59248.1
BT014903 mRNA Translation: AAT46032.1
BT015753 mRNA Translation: AAU84690.1
PIRiD86270
RefSeqiNP_001318995.1, NM_001332082.1
NP_001321621.1, NM_001332083.1
NP_172826.1, NM_101239.4
UniGeneiAt.42014
At.66943

Genome annotation databases

EnsemblPlantsiAT1G13700.1; AT1G13700.1; AT1G13700
AT1G13700.2; AT1G13700.2; AT1G13700
AT1G13700.3; AT1G13700.3; AT1G13700
GeneIDi837931
GrameneiAT1G13700.1; AT1G13700.1; AT1G13700
AT1G13700.2; AT1G13700.2; AT1G13700
AT1G13700.3; AT1G13700.3; AT1G13700
KEGGiath:AT1G13700

Similar proteinsi

Entry informationi

Entry namei6PGL1_ARATH
AccessioniPrimary (citable) accession number: Q9LMX8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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