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Q9LMN1 (PI5KA_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphatidylinositol 4-phosphate 5-kinase 10

Short name=AtPIP5K10
EC=2.7.1.68
Alternative name(s):
1-phosphatidylinositol 4-phosphate kinase 10
Diphosphoinositide kinase 10
PtdIns(4)P-5-kinase 10
Gene names
Name:PIP5K10
Ordered Locus Names:At1g01460
ORF Names:F22L4.2
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length427 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

Sequence similarities

Contains 1 PIPK domain.

Sequence caution

The sequence AAF81306.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 427427Phosphatidylinositol 4-phosphate 5-kinase 10
PRO_0000185482

Regions

Domain1 – 419419PIPK
Region379 – 40022Activation loop By similarity
Compositional bias244 – 32986Ser-rich

Sequences

Sequence LengthMass (Da)Tools
Q9LMN1 [UniParc].

Last modified October 25, 2005. Version 2.
Checksum: 87EDC9019FAFC28F

FASTA42748,549
        10         20         30         40         50         60 
MFTREITAKD VKATEKNRIR YSSKHIKHLP PGTITEFEWK DYCPLGFRLI QELEDINHDE 

        70         80         90        100        110        120 
YMKSICNDET LRKLSTSKVG NMFLLSKDDR FLIKILRKSE IKVILEMLPG YFRHIHKYRS 

       130        140        150        160        170        180 
TLLSKNYGAH SVKPIGGVKT YFVVMSNILQ SDVFMNKVYD LKGSSQGRTN KKIKVRDKTI 

       190        200        210        220        230        240 
LKDIDLDFCF YVDSLARHRL IKQTKLDCEL LEDEGIMDYS LMLGLQVKGS CHGSIDELIP 

       250        260        270        280        290        300 
VYDSFTSRGS VDSNSSKFMK TASNSPDRSS STMYSCTPSR NSVDSENSVN IQSVASISPS 

       310        320        330        340        350        360 
PAQTNASDSP YESLVSKTNL TNIFQNSSST NFGMKIPGRA RRVGRGESGS VVGKQSREGG 

       370        380        390        400        410        420 
EEWYDVILYL GIIDIFQDYG VRKRLEHCYK SIQHSSKTIS AVHPKMYSSR FQDFVSQIFL 


PDEDPSH 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of a 40-kb Arabidopsis thaliana genomic region located at the top of chromosome 1."
Terryn N., Gielen J., De Keyser A., Van Den Daele H., Ardiles W., Neyt P., De Clercq R., Coppieters J., Dehais P., Villarroel R., Rouze P., van Montagu M.
Gene 215:11-17(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W., Redman J.C., Wu H.C., Utterback T., Town C.D.
Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C."
Mueller-Roeber B., Pical C.
Plant Physiol. 130:22-46(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y12776 Genomic DNA. Translation: CAA73312.1.
AC061957 Genomic DNA. Translation: AAF81306.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE27290.1.
DQ056443 mRNA. Translation: AAY78600.1.
PIRC86145.
RefSeqNP_171653.2. NM_100028.2.
UniGeneAt.49838.

3D structure databases

ProteinModelPortalQ9LMN1.
SMRQ9LMN1. Positions 10-226.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G01460.1; AT1G01460.1; AT1G01460.
GeneID839469.
KEGGath:AT1G01460.

Organism-specific databases

TAIRAT1G01460.

Phylogenomic databases

eggNOGCOG5253.
HOGENOMHOG000193875.
InParanoidQ9LMN1.
KOK00889.
OMACELLEDE.
PhylomeDBQ9LMN1.

Enzyme and pathway databases

BioCycARA:AT1G01460-MONOMER.
BRENDA2.7.1.68. 399.

Gene expression databases

GenevestigatorQ9LMN1.

Family and domain databases

Gene3D3.30.800.10. 1 hit.
3.30.810.10. 2 hits.
InterProIPR023610. PInositol-4-P-5-kinase.
IPR027483. PInositol-4-P-5-kinase_C.
IPR002498. PInositol-4-P-5-kinase_core.
IPR027484. PInositol-4-P-5-kinase_N.
IPR016034. PInositol-4P-5-kinase_core_sub.
[Graphical view]
PANTHERPTHR23086. PTHR23086. 1 hit.
PfamPF01504. PIP5K. 1 hit.
[Graphical view]
SMARTSM00330. PIPKc. 1 hit.
[Graphical view]
PROSITEPS51455. PIPK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePI5KA_ARATH
AccessionPrimary (citable) accession number: Q9LMN1
Secondary accession number(s): O23705
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 25, 2005
Last modified: May 14, 2014
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names