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Q9LKP7

- CHSY_DIAMO

UniProt

Q9LKP7 - CHSY_DIAMO

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Protein

Chalcone synthase

Gene

CHS

Organism
Dianthus monspessulanus
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641PROSITE-ProRule annotation

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase
Gene namesi
Name:CHS
OrganismiDianthus monspessulanus
Taxonomic identifieri129769 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesCaryophyllaceaeDianthus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 391391Chalcone synthasePRO_0000215974Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9LKP7.
SMRiQ9LKP7. Positions 3-389.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LKP7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASIEEIRQA QRADGPATIL AIGTATPPNA IYQADYPDYY FRVTKSEHMT
60 70 80 90 100
ELKEKFRRMC DKSMIKKRYM YLTEEILKEN PNLCEYMGSS LDTRQDMVVS
110 120 130 140 150
EVPRLGKEAA VKAIKEWGQP KSKITHVIMC TTSGVDMPGA DYQLTKLLGL
160 170 180 190 200
RPSVRRFMLY QQGCFAGGTV LRLAKDLAEN NKGARVLVVC SEITAICFRG
210 220 230 240 250
PTEAALDSMV GQALFGDGAG ALIVGSDPDL SIERPLFQMA WAGQTLLPDS
260 270 280 290 300
EGAIDGHLRE VGLTFHLLKD VPGIISKNIT NALEEAFSPI GVSDWNNLFW
310 320 330 340 350
IAHPGGPAIL DQVEAKLGLK EEKLAATRNV LSDFGNMSSA CVLFILDEMR
360 370 380 390
KKSLRDGATT TGEGLDWGVL FGFGPGLTVE TVVLHSVPLN C
Length:391
Mass (Da):42,766
Last modified:October 1, 2000 - v1
Checksum:i7C132D24E66C6C5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF267173 mRNA. Translation: AAF81743.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF267173 mRNA. Translation: AAF81743.1 .

3D structure databases

ProteinModelPortali Q9LKP7.
SMRi Q9LKP7. Positions 3-389.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning of chalcone synthase cDNA from Dianthus monspessulanus."
    Yagishita Y., Ohya T., Kaminishi A., Nomura K., Kita N.
    Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiCHSY_DIAMO
AccessioniPrimary (citable) accession number: Q9LKP7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: October 1, 2000
Last modified: October 1, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3