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Protein

Transcription factor MYB21

Gene

MYB21

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Transcription factor involved in photomorphogenesis in the light. May act downstream of the light receptor network and directly affects transcription of light-induced genes. In darkness, its probable degradation prevent the activation of light-induced genes. Required to activate expression of PAL. Acts redundantly with MYB24 and MYB57 to control stamen filament elongation in the late developed flowers. Contributes with MYB24 to induction of MYB108 by jasmonate. Repressed at the transcript levels by DELLA proteins.5 Publications

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi45 – 6925H-T-H motifPROSITE-ProRule annotationAdd
BLAST
DNA bindingi97 – 12024H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • gibberellic acid mediated signaling pathway Source: TAIR
  • jasmonic acid mediated signaling pathway Source: TAIR
  • red, far-red light phototransduction Source: UniProtKB-KW
  • regulation of transcription, DNA-templated Source: UniProtKB-KW
  • response to jasmonic acid Source: TAIR
  • stamen development Source: TAIR
  • stamen filament development Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Phytochrome signaling pathway, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor MYB21
Alternative name(s):
Myb homolog 3
Short name:
AtMyb3
Myb-related protein 21
Short name:
AtMYB21
Gene namesi
Name:MYB21
Synonyms:MYB3
Ordered Locus Names:At3g27810
ORF Names:MGF10.23
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G27810.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Short anther filaments, delayed anther dehiscence and greatly reduced male fertility. Myb21 and myb24 double mutant is more severely sterile than myb21 mutant and has petals that just grew out of the sepals but ended at a lower level than the stigma. Myb21 and myb57 double mutant has an intermediate sterility phenotype and petals that grew to a final height parallel to the pistil. Myb21, myb24 and myb57 triple mutant has a strongly reduced fertility and an arrested growth of the petals that never grew out of the sepals.2 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226Transcription factor MYB21PRO_0000197076Add
BLAST

Post-translational modificationi

Probably ubiquitinated by COP1. Ubiquitination takes place in darkness and leads to its subsequent degradation, thereby preventing to activate photomorphogenesis signals (Probable).Curated

Keywords - PTMi

Ubl conjugation

Proteomic databases

PaxDbiQ9LK95.

Expressioni

Tissue specificityi

Mainly expressed in floral tissues. expressed in all four whorls of the flower, in the anther vascular tissue and in cells at the junction between anther and stamen filaments. Detected in the nectaries and ovules.3 Publications

Inductioni

Up-regulated by jasmonate.1 Publication

Gene expression databases

GenevisibleiQ9LK95. AT.

Interactioni

Subunit structurei

Interacts (via N-terminus) with TIFY10A/JAZ1, TIFY5A/JAZ8 AND TIFY3A/JAZ11.1 Publication

Protein-protein interaction databases

BioGridi7731. 10 interactions.
STRINGi3702.AT3G27810.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LK95.
SMRiQ9LK95. Positions 19-124.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini17 – 6953HTH myb-type 1PROSITE-ProRule annotationAdd
BLAST
Domaini70 – 12455HTH myb-type 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 HTH myb-type DNA-binding domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0048. Eukaryota.
COG5147. LUCA.
HOGENOMiHOG000237600.
InParanoidiQ9LK95.
KOiK09422.
OMAiADYSIPM.
OrthoDBiEOG09360L45.
PhylomeDBiQ9LK95.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR017930. Myb_dom.
IPR001005. SANT/Myb.
[Graphical view]
PfamiPF00249. Myb_DNA-binding. 2 hits.
[Graphical view]
SMARTiSM00717. SANT. 2 hits.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS51294. HTH_MYB. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LK95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKRGGGSSG GSGSSAEAEV RKGPWTMEED LILINYIANH GDGVWNSLAK
60 70 80 90 100
SAGLKRTGKS CRLRWLNYLR PDVRRGNITP EEQLIIMELH AKWGNRWSKI
110 120 130 140 150
AKHLPGRTDN EIKNFWRTRI QKYIKQSDVT TTSSVGSHHS SEINDQAAST
160 170 180 190 200
SSHNVFCTQD QAMETYSPTP TSYQHTNMEF NYGNYSAAAV TATVDYPVPM
210 220
TVDDQTGENY WGMDDIWSSM HLLNGN
Length:226
Mass (Da):25,351
Last modified:October 1, 2000 - v1
Checksum:iD29479EBFD1D59CC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti116 – 1161W → C in BAA21618 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB005888 mRNA. Translation: BAA21618.1.
AP000371, AB018114 Genomic DNA. Translation: BAB02527.1.
CP002686 Genomic DNA. Translation: AEE77366.1.
AY519589 mRNA. Translation: AAS10059.1.
AK118439 mRNA. Translation: BAC43048.1.
AB493635 mRNA. Translation: BAH30473.1.
AF062870 mRNA. Translation: AAC83592.1.
PIRiT51642.
RefSeqiNP_189418.2. NM_113696.2.
UniGeneiAt.226.

Genome annotation databases

EnsemblPlantsiAT3G27810.1; AT3G27810.1; AT3G27810.
GeneIDi822401.
GrameneiAT3G27810.1; AT3G27810.1; AT3G27810.
KEGGiath:AT3G27810.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB005888 mRNA. Translation: BAA21618.1.
AP000371, AB018114 Genomic DNA. Translation: BAB02527.1.
CP002686 Genomic DNA. Translation: AEE77366.1.
AY519589 mRNA. Translation: AAS10059.1.
AK118439 mRNA. Translation: BAC43048.1.
AB493635 mRNA. Translation: BAH30473.1.
AF062870 mRNA. Translation: AAC83592.1.
PIRiT51642.
RefSeqiNP_189418.2. NM_113696.2.
UniGeneiAt.226.

3D structure databases

ProteinModelPortaliQ9LK95.
SMRiQ9LK95. Positions 19-124.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi7731. 10 interactions.
STRINGi3702.AT3G27810.1.

Proteomic databases

PaxDbiQ9LK95.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G27810.1; AT3G27810.1; AT3G27810.
GeneIDi822401.
GrameneiAT3G27810.1; AT3G27810.1; AT3G27810.
KEGGiath:AT3G27810.

Organism-specific databases

TAIRiAT3G27810.

Phylogenomic databases

eggNOGiKOG0048. Eukaryota.
COG5147. LUCA.
HOGENOMiHOG000237600.
InParanoidiQ9LK95.
KOiK09422.
OMAiADYSIPM.
OrthoDBiEOG09360L45.
PhylomeDBiQ9LK95.

Miscellaneous databases

PROiQ9LK95.

Gene expression databases

GenevisibleiQ9LK95. AT.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR017930. Myb_dom.
IPR001005. SANT/Myb.
[Graphical view]
PfamiPF00249. Myb_DNA-binding. 2 hits.
[Graphical view]
SMARTiSM00717. SANT. 2 hits.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS51294. HTH_MYB. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMYB21_ARATH
AccessioniPrimary (citable) accession number: Q9LK95
Secondary accession number(s): C0SVD2, O22684, Q9SBG4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: October 1, 2000
Last modified: September 7, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.