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Protein

Transcription factor MYB21

Gene

MYB21

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcription factor involved in photomorphogenesis in the light. May act downstream of the light receptor network and directly affects transcription of light-induced genes. In darkness, its probable degradation prevent the activation of light-induced genes. Required to activate expression of PAL. Acts redundantly with MYB24 and MYB57 to control stamen filament elongation in the late developed flowers. Contributes with MYB24 to induction of MYB108 by jasmonate. Repressed at the transcript levels by DELLA proteins.5 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi45 – 69H-T-H motifPROSITE-ProRule annotationAdd BLAST25
DNA bindingi97 – 120H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

  • cell differentiation Source: GO_Central
  • gibberellic acid mediated signaling pathway Source: TAIR
  • jasmonic acid mediated signaling pathway Source: TAIR
  • red, far-red light phototransduction Source: UniProtKB-KW
  • regulation of transcription by RNA polymerase II Source: GO_Central
  • response to jasmonic acid Source: TAIR
  • stamen development Source: TAIR
  • stamen filament development Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, DNA-binding
Biological processPhytochrome signaling pathway, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor MYB21
Alternative name(s):
Myb homolog 3
Short name:
AtMyb3
Myb-related protein 21
Short name:
AtMYB21
Gene namesi
Name:MYB21
Synonyms:MYB3
Ordered Locus Names:At3g27810
ORF Names:MGF10.23
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G27810
TAIRilocus:2089159 AT3G27810

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Short anther filaments, delayed anther dehiscence and greatly reduced male fertility. Myb21 and myb24 double mutant is more severely sterile than myb21 mutant and has petals that just grew out of the sepals but ended at a lower level than the stigma. Myb21 and myb57 double mutant has an intermediate sterility phenotype and petals that grew to a final height parallel to the pistil. Myb21, myb24 and myb57 triple mutant has a strongly reduced fertility and an arrested growth of the petals that never grew out of the sepals.2 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001970761 – 226Transcription factor MYB21Add BLAST226

Post-translational modificationi

Probably ubiquitinated by COP1. Ubiquitination takes place in darkness and leads to its subsequent degradation, thereby preventing to activate photomorphogenesis signals (Probable).Curated

Keywords - PTMi

Ubl conjugation

Proteomic databases

PaxDbiQ9LK95

Expressioni

Tissue specificityi

Mainly expressed in floral tissues. expressed in all four whorls of the flower, in the anther vascular tissue and in cells at the junction between anther and stamen filaments. Detected in the nectaries and ovules.3 Publications

Inductioni

Up-regulated by jasmonate.1 Publication

Gene expression databases

ExpressionAtlasiQ9LK95 baseline and differential
GenevisibleiQ9LK95 AT

Interactioni

Subunit structurei

Interacts (via N-terminus) with TIFY10A/JAZ1, TIFY5A/JAZ8 AND TIFY3A/JAZ11.1 Publication

Protein-protein interaction databases

BioGridi7731, 10 interactors
IntActiQ9LK95, 4 interactors
STRINGi3702.AT3G27810.1

Structurei

3D structure databases

ProteinModelPortaliQ9LK95
SMRiQ9LK95
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 69HTH myb-type 1PROSITE-ProRule annotationAdd BLAST53
Domaini70 – 124HTH myb-type 2PROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0048 Eukaryota
COG5147 LUCA
HOGENOMiHOG000237600
InParanoidiQ9LK95
KOiK09422
OMAiADYPVPM
OrthoDBiEOG09360L45
PhylomeDBiQ9LK95

Family and domain databases

CDDicd00167 SANT, 2 hits
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017930 Myb_dom
IPR001005 SANT/Myb
PfamiView protein in Pfam
PF00249 Myb_DNA-binding, 2 hits
SMARTiView protein in SMART
SM00717 SANT, 2 hits
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51294 HTH_MYB, 2 hits

Sequencei

Sequence statusi: Complete.

Q9LK95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKRGGGSSG GSGSSAEAEV RKGPWTMEED LILINYIANH GDGVWNSLAK
60 70 80 90 100
SAGLKRTGKS CRLRWLNYLR PDVRRGNITP EEQLIIMELH AKWGNRWSKI
110 120 130 140 150
AKHLPGRTDN EIKNFWRTRI QKYIKQSDVT TTSSVGSHHS SEINDQAAST
160 170 180 190 200
SSHNVFCTQD QAMETYSPTP TSYQHTNMEF NYGNYSAAAV TATVDYPVPM
210 220
TVDDQTGENY WGMDDIWSSM HLLNGN
Length:226
Mass (Da):25,351
Last modified:October 1, 2000 - v1
Checksum:iD29479EBFD1D59CC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti116W → C in BAA21618 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB005888 mRNA Translation: BAA21618.1
AP000371, AB018114 Genomic DNA Translation: BAB02527.1
CP002686 Genomic DNA Translation: AEE77366.1
AY519589 mRNA Translation: AAS10059.1
AK118439 mRNA Translation: BAC43048.1
AB493635 mRNA Translation: BAH30473.1
AF062870 mRNA Translation: AAC83592.1
PIRiT51642
RefSeqiNP_189418.2, NM_113696.3
UniGeneiAt.226

Genome annotation databases

EnsemblPlantsiAT3G27810.1; AT3G27810.1; AT3G27810
GeneIDi822401
GrameneiAT3G27810.1; AT3G27810.1; AT3G27810
KEGGiath:AT3G27810

Similar proteinsi

Entry informationi

Entry nameiMYB21_ARATH
AccessioniPrimary (citable) accession number: Q9LK95
Secondary accession number(s): C0SVD2, O22684, Q9SBG4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health