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Protein

Cytochrome c1 1, heme protein, mitochondrial

Gene

CYC11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei103Heme (covalent)PROSITE-ProRule annotation1
Binding sitei106Heme (covalent)PROSITE-ProRule annotation1
Metal bindingi107Iron (heme axial ligand)PROSITE-ProRule annotation1
Metal bindingi226Iron (heme axial ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT3G27240-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c1 1, heme protein, mitochondrial
Alternative name(s):
Complex III subunit 4-1
Complex III subunit IV-1
Cytochrome b-c1 complex subunit 4-1
Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit 1
Short name:
Cytochrome c-1 1
Gene namesi
Name:CYC11
Ordered Locus Names:At3g27240
ORF Names:K17E12.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G27240
TAIRilocus:2086553 AT3G27240

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei268 – 288Helical; Note=Anchors to the membraneSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 64MitochondrionSequence analysisAdd BLAST64
ChainiPRO_000042867265 – 307Cytochrome c1 1, heme protein, mitochondrialAdd BLAST243

Post-translational modificationi

Binds 1 heme group per subunit.By similarity

Proteomic databases

PaxDbiQ9LK29
PRIDEiQ9LK29

Expressioni

Gene expression databases

ExpressionAtlasiQ9LK29 baseline and differential
GenevisibleiQ9LK29 AT

Interactioni

Subunit structurei

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. Associated to the mitochondrial respiratory chain complex III.1 Publication

Protein-protein interaction databases

IntActiQ9LK29, 3 interactors
STRINGi3702.AT3G27240.1

Structurei

3D structure databases

ProteinModelPortaliQ9LK29
SMRiQ9LK29
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini90 – 246Cytochrome cPROSITE-ProRule annotationAdd BLAST157

Sequence similaritiesi

Belongs to the cytochrome c family.Curated

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3052 Eukaryota
COG2857 LUCA
HOGENOMiHOG000003867
InParanoidiQ9LK29
KOiK00413
OMAiSRKIAYR
OrthoDBiEOG09360JHE
PhylomeDBiQ9LK29

Family and domain databases

Gene3Di1.10.760.10, 1 hit
InterProiView protein in InterPro
IPR009056 Cyt_c-like_dom
IPR036909 Cyt_c-like_dom_sf
IPR002326 Cyt_c1
IPR021157 Cyt_c1_TM_anchor_C
PANTHERiPTHR10266 PTHR10266, 1 hit
PfamiView protein in Pfam
PF02167 Cytochrom_C1, 1 hit
PRINTSiPR00603 CYTOCHROMEC1
SUPFAMiSSF46626 SSF46626, 1 hit
SSF81496 SSF81496, 1 hit
PROSITEiView protein in PROSITE
PS51007 CYTC, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9LK29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGGGVIQQI LRRKLHSQSL ATPVLSWFSS KKAHEDAGSS GVRALALLGA
60 70 80 90 100
GVTGLLSFST VASADEAEHG LESPEYPWPH DGILSSYDHA SIRRGHQVYQ
110 120 130 140 150
QVCASCHSMS LISYRDLVGV AYTEEEAKAM AAEIEVVDGP NDEGEMFTRP
160 170 180 190 200
GKLSDRFPQP YANESAARFA NGGAYPPDLS LITKARHNGP NYVFALLTGY
210 220 230 240 250
RDPPAGISIR EGLHYNPYFP GGAIAMPKML NDEAVEYEDG VPATEAQMGK
260 270 280 290 300
DIVSFLAWAA EPEMEERKLM GFKWIFLLSL ALLQAAYYRR LKWSVLKSRK

LVLDVVN
Length:307
Mass (Da):33,650
Last modified:October 1, 2000 - v1
Checksum:iD041537B37D84C03
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti53T → S in AAM65645 (Ref. 4) Curated1
Sequence conflicti123T → A in AAL51110 (PubMed:14593172).Curated1
Sequence conflicti123T → A in AAL06905 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000381 Genomic DNA Translation: BAB02119.1
CP002686 Genomic DNA Translation: AEE77282.1
AF458338 mRNA Translation: AAL51110.1
AY054246 mRNA Translation: AAL06905.1
AY088099 mRNA Translation: AAM65645.1
RefSeqiNP_189360.1, NM_113638.3
UniGeneiAt.25451

Genome annotation databases

EnsemblPlantsiAT3G27240.1; AT3G27240.1; AT3G27240
GeneIDi822343
GrameneiAT3G27240.1; AT3G27240.1; AT3G27240
KEGGiath:AT3G27240

Similar proteinsi

Entry informationi

Entry nameiCYC1A_ARATH
AccessioniPrimary (citable) accession number: Q9LK29
Secondary accession number(s): Q8LA08, Q940N2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 16, 2014
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health