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Protein

Beta-glucosidase 19

Gene

BGLU19

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei52 – 521SubstrateBy similarity
Binding sitei155 – 1551SubstrateBy similarity
Binding sitei200 – 2001SubstrateBy similarity
Active sitei201 – 2011Proton donorBy similarity
Binding sitei345 – 3451SubstrateBy similarity
Active sitei418 – 4181NucleophileBy similarity
Binding sitei469 – 4691SubstrateBy similarity

GO - Molecular functioni

  1. beta-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciARA:AT3G21370-MONOMER.

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-glucosidase 19 (EC:3.2.1.21)
Short name:
AtBGLU19
Gene namesi
Name:BGLU19
Ordered Locus Names:At3g21370
ORF Names:MHC9.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 3

Organism-specific databases

TAIRiAT3G21370.

Subcellular locationi

Endoplasmic reticulum lumen PROSITE-ProRule annotation

GO - Cellular componenti

  1. endoplasmic reticulum lumen Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence AnalysisAdd
BLAST
Chaini22 – 527506Beta-glucosidase 19PRO_0000389581Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi183 – 1831N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi220 ↔ 231By similarity
Glycosylationi462 – 4621N-linked (GlcNAc...)Sequence Analysis
Glycosylationi495 – 4951N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9LIF9.
PRIDEiQ9LIF9.

Expressioni

Gene expression databases

ExpressionAtlasiQ9LIF9. baseline and differential.
GenevestigatoriQ9LIF9.

Interactioni

Protein-protein interaction databases

IntActiQ9LIF9. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ9LIF9.
SMRiQ9LIF9. Positions 33-512.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni476 – 4772Substrate bindingBy similarity

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi524 – 5274Prevents secretion from ERPROSITE-ProRule annotation

Sequence similaritiesi

Belongs to the glycosyl hydrolase 1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG2723.
HOGENOMiHOG000088630.
InParanoidiQ9LIF9.
KOiK01188.
OMAiVEYANFT.
PhylomeDBiQ9LIF9.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9LIF9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKIPLLGLLL LISLVGSPTR AEEGPVCPKT ETLSRASFPE GFMFGTATAA
60 70 80 90 100
FQVEGAVNEG CRGPSLWDIY TKKFPHRVKN HNADEAVDFY HRYKEDIQLM
110 120 130 140 150
KKLNTDGFRL SISWPRIFPH GRMEKGISKE GVQFYHDLID ELLKNDITPL
160 170 180 190 200
VTVFHWDTPA DLEDEYGGFL SERIVPDFVE YANFTFHEYG DKVKNWITFN
210 220 230 240 250
EPWVFSRSGY DVGKKAPGRC SPYVKEFGKL CQDGRSGFEP YVVSHNLLVG
260 270 280 290 300
HAEAVDAFRK CEKCKGGKIG IAHSPAWFEP EDVEGGQATV NRVLDFVIGW
310 320 330 340 350
HLDPTTFGDY PQSMKDAVGS RLPRFTKAQK AKLKDSTDFV GINYYTSFFA
360 370 380 390 400
KADQKVDSRN PTWATDALVE FEPKTVDGSI KIGSQPNTAK MAVYAKGLRK
410 420 430 440 450
LMKYIKDRYN SPEIIITENG YGEDLGDKDT DLSVALNDHN RKYYLQRHLL
460 470 480 490 500
ALNEAICEDK VNVTSYFLWS LMDNFEWQDG YTARFGVYYI DFKNNLTRME
510 520
KESAKWLSEF LKPGLKPSKS SKLHEEL
Length:527
Mass (Da):60,015
Last modified:October 1, 2000 - v1
Checksum:iA9EB34BC818BF88A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti349 – 3491F → L in AAL24252. (PubMed:14593172)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001305 Genomic DNA. Translation: BAB03050.1.
CP002686 Genomic DNA. Translation: AEE76501.1.
AY058865 mRNA. Translation: AAL24252.1.
AY064046 mRNA. Translation: AAL36402.1.
AY096383 mRNA. Translation: AAM20024.1.
RefSeqiNP_188774.2. NM_113032.3.
UniGeneiAt.47366.
At.63567.

Genome annotation databases

EnsemblPlantsiAT3G21370.1; AT3G21370.1; AT3G21370.
GeneIDi821691.
KEGGiath:AT3G21370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001305 Genomic DNA. Translation: BAB03050.1.
CP002686 Genomic DNA. Translation: AEE76501.1.
AY058865 mRNA. Translation: AAL24252.1.
AY064046 mRNA. Translation: AAL36402.1.
AY096383 mRNA. Translation: AAM20024.1.
RefSeqiNP_188774.2. NM_113032.3.
UniGeneiAt.47366.
At.63567.

3D structure databases

ProteinModelPortaliQ9LIF9.
SMRiQ9LIF9. Positions 33-512.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9LIF9. 1 interaction.

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Proteomic databases

PaxDbiQ9LIF9.
PRIDEiQ9LIF9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G21370.1; AT3G21370.1; AT3G21370.
GeneIDi821691.
KEGGiath:AT3G21370.

Organism-specific databases

TAIRiAT3G21370.

Phylogenomic databases

eggNOGiCOG2723.
HOGENOMiHOG000088630.
InParanoidiQ9LIF9.
KOiK01188.
OMAiVEYANFT.
PhylomeDBiQ9LIF9.

Enzyme and pathway databases

BioCyciARA:AT3G21370-MONOMER.

Gene expression databases

ExpressionAtlasiQ9LIF9. baseline and differential.
GenevestigatoriQ9LIF9.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
    Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.
    DNA Res. 7:217-221(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiBGL19_ARATH
AccessioniPrimary (citable) accession number: Q9LIF9
Secondary accession number(s): Q93Z07
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: October 1, 2000
Last modified: January 7, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.