Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q9LI83 (ALA10_ARATH)

Last modified June 16, 2009. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Putative phospholipid-transporting ATPase 10
      Short name=AtALA10
    EC=3.6.3.1
Alternative name(s):
    Aminophospholipid flippase 10
Gene names
Name: ALA10
Ordered Locus Names: At3g25610
ORF Names: T5M7.5
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Hide | Top

Protein attributes

Sequence length1202 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

Hide | Top

General annotation (Comments)

Function

Involved in transport of phospholipids Potential.

Catalytic activity

ATP + H2O + phospholipid(In) = ADP + phosphate + phospholipid(Out).

Subcellular location

Cell membrane; Multi-pass membrane protein Probable.

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. Type IV subfamily.

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12021202Putative phospholipid-transporting ATPase 10
PRO_0000046394

Regions

Topological domain1 – 7373Cytoplasmic Potential
Transmembrane74 – 9522 Potential
Topological domain96 – 994Extracellular Potential
Transmembrane100 – 12223 Potential
Topological domain123 – 305183Cytoplasmic Potential
Transmembrane306 – 32722 Potential
Topological domain328 – 36437Extracellular Potential
Transmembrane365 – 38218 Potential
Topological domain383 – 920538Cytoplasmic Potential
Transmembrane921 – 94020 Potential
Topological domain941 – 95414Extracellular Potential
Transmembrane955 – 97420 Potential
Topological domain975 – 100430Cytoplasmic Potential
Transmembrane1005 – 102723 Potential
Topological domain1028 – 104013Extracellular Potential
Transmembrane1041 – 106323 Potential
Topological domain1064 – 10696Cytoplasmic Potential
Transmembrane1070 – 109021 Potential
Topological domain1091 – 110717Extracellular Potential
Transmembrane1108 – 113225 Potential
Topological domain1133 – 120270Cytoplasmic Potential

Sites

Active site43014-aspartylphosphate intermediate By similarity
Metal binding8651Magnesium By similarity
Metal binding8691Magnesium By similarity

Amino acid modifications

Modified residue311Phosphoserine Ref.2

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q9LI83-1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 5930D14DB7942547

FASTA1,202136,279
        10         20         30         40         50         60 
MAGPSRRRRR LHLSKIYSYT CGKSSFQEDH SNIGGPGFSR VVYCNEPGSP AAERRNYAGN 

        70         80         90        100        110        120 
YVRSTKYTVA SFFPKSLFEQ FRRVANFYFL VTGILSLTDL SPYGAVSALL PLALVISATM 

       130        140        150        160        170        180 
VKEGIEDWRR KQQDIEVNNR KVKVHDGNGI FRQEEWRNLR VGDIVRVEKD EFFPADLLLL 

       190        200        210        220        230        240 
SSSYEDSVCY VETMNLDGET NLKVKQGLEA TSSLLNQDSD FKDFRGVVRC EDPNVNLYVF 

       250        260        270        280        290        300 
VGTLALEEER FPLSIQQILL RDSKLRNTEY VYGAVVFTGH DTKVIQNSTD PPSKRSRIER 

       310        320        330        340        350        360 
TMDKIIYLMF GLVFLMSFVG SIIFGVETRE DKVKNGRTER WYLKPDDADI FFDPERAPMA 

       370        380        390        400        410        420 
AIYHFFTATM LYSYFIPISL YVSIEIVKVL QSIFINRDIH MYYEETDKPA QARTSNLNEE 

       430        440        450        460        470        480 
LGMVDTILSD KTGTLTCNSM EFIKCSIAGK AYGRGITEVE RAMAVRSGGS PLVNEDLDVV 

       490        500        510        520        530        540 
VDQSGPKVKG FNFEDERVMN GNWVRQPEAA VLQKFFRLLA VCHTAIPETD EESGNVSYEA 

       550        560        570        580        590        600 
ESPDEAAFVV AAREFGFEFF NRTQNGISFR ELDLVSGEKV ERVYRLLNVL EFNSTRKRMS 

       610        620        630        640        650        660 
VIVRDDDGKL LLLSKGADNV MFERLAKNGR QFEAKTQEHV NQYADAGLRT LVLAYREVDE 

       670        680        690        700        710        720 
NEYIEFNKSF NEAKASVSED REALIDEITD KMERDLILLG ATAVEDKLQN GVPECIDKLA 

       730        740        750        760        770        780 
QAGIKIWVLT GDKMETAINI GFASSLLRQE MKQIIINLET PQIKSLEKSG GKDEIELASR 

       790        800        810        820        830        840 
ESVVMQLQEG KALLAASGAS SEAFALIIDG KSLTYALEDE IKKMFLDLAT SCASVICCRS 

       850        860        870        880        890        900 
SPKQKALVTR LVKSGTGKTT LAIGDGANDV GMLQEADIGV GISGVEGMQA VMSSDIAIAQ 

       910        920        930        940        950        960 
FRYLERLLLV HGHWCYSRIA SMICYFFYKN ITFGVTVFLY EAYTSFSGQP AYNDWFLSLF 

       970        980        990       1000       1010       1020 
NVFFSSLPVI ALGVFDQDVS ARFCYKFPLL YQEGVQNILF SWKRIIGWMF NGFISALAIF 

      1030       1040       1050       1060       1070       1080 
FLCKESLKHQ LFDPDGKTAG REILGGTMYT CVVWVVNLQM ALSISYFTWV QHIVIWGSIA 

      1090       1100       1110       1120       1130       1140 
FWYIFLMIYG AMTPSFSTDA YMVFLEALAP APSYWLTTLF VMIFALIPYF VYKSVQMRFF 

      1150       1160       1170       1180       1190       1200 
PKYHQMIQWI RYEGHSNDPE FVEMVRQRSI RPTTVGYTAR RAASVRRSAR FHDQIYKDLV 


GV

« Hide

Hide | Top

References

[1]"Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.
DNA Res. 7:217-221(2000) [PubMed: 10907853] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]"Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database."
Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.
Plant Cell 16:2394-2405(2004) [PubMed: 15308754] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-31, SUBCELLULAR LOCATION, MASS SPECTROMETRY.

Hide | Top

Cross-references

Sequence databases

AP001313 Genomic DNA. Translation: BAB03080.1.
IPIIPI00525000.
RefSeqNP_189189.1.
UniGeneAt.49391

3D structure databases

ModBaseSearch...

Proteomic databases

PRIDEQ9LI83.

Genome annotation databases

GeneID822148.
GenomeReviewsGene locus AT3G25610 in contig BA000014_GR.
KEGGath:AT3G25610.
NMPDRfig|3702.1.peg.14817.

Organism-specific databases

TAIRAt3g25610.

Phylogenomic databases

OMAQ9LI83. RIASMIC.

Enzyme and pathway databases

BRENDA3.6.3.1. 302.

Gene expression databases

ArrayExpressQ9LI83.
GermOnlineAT3G25610. Arabidopsis thaliana.

Family and domain databases

InterProIPR008250. ATPase_P-typ_ATPase-assoc-reg.
IPR001757. ATPase_P-typ_ion-transptr.
IPR018303. ATPase_P-typ_phosphor_site.
IPR006539. ATPase_P-typ_Plipid-transl.
IPR005834. Dehalogen-like_hydro.
IPR013200. HAD-SF_hydro-like_3.
[Graphical view]
PANTHERPTHR11939. ATPase_P. 1 hit.
PfamPF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
PF08282. Hydrolase_3. 1 hit.
[Graphical view]
PRINTSPR00119. CATATPASE.
TIGRFAMsTIGR01652. ATPase-Plipid. 1 hit.
TIGR01494. ATPase_P-type. 4 hits.
PROSITEPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry nameALA10_ARATH
AccessionPrimary (citable) accession number: Q9LI83
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: October 1, 2000
Last modified: June 16, 2009
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Hide | Top

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents