Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative ABC transporter B family member 8

Gene

ABCB8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein uncertaini

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi395 – 402ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1033 – 1040ATP 2PROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ABC transporter B family member 8
Short name:
ABC transporter ABCB.8
Short name:
AtABCB8
Alternative name(s):
P-glycoprotein 8
Putative multidrug resistance protein 22
Gene namesi
Name:ABCB8
Synonyms:MDR22, PGP8
Ordered Locus Names:At3g30875
ORF Names:MJI6.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G30875.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 44HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei82 – 102HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei157 – 177HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei183 – 203HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei263 – 283HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei297 – 317HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei686 – 706HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei716 – 736HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei797 – 815HelicalPROSITE-ProRule annotationAdd BLAST19
Transmembranei821 – 838HelicalPROSITE-ProRule annotationAdd BLAST18
Transmembranei899 – 919HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei933 – 953HelicalPROSITE-ProRule annotationAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002279331 – 1241Putative ABC transporter B family member 8Add BLAST1241

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi48N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi571N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi632N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi648N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi773N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi855N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1187N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ9LHK4.
SMRiQ9LHK4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 323ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST291
Domaini360 – 596ABC transporter 1PROSITE-ProRule annotationAdd BLAST237
Domaini676 – 964ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST289
Domaini998 – 1236ABC transporter 2PROSITE-ProRule annotationAdd BLAST239

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ9LHK4.

Family and domain databases

Gene3Di1.20.1560.10. 2 hits.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR036640. ABC1_TM_sf.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9LHK4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSQAKTETV SSKSSRNTHV IFRFADWIDI VLMVLGSVGA IGDGMSTNVS
60 70 80 90 100
LVFVSRIMNT LGYSQHNPSS TNFKEEIQKC SLYFVYLGLA ILGVAFMEGY
110 120 130 140 150
CWSKTSERQV MKIRRTYLEA VLRQEVSFFD SDISTSEIIH TISTDTSLIQ
160 170 180 190 200
QLLSEKVPIF LMHISVFITG LVFSAYFSWR LTVVAIPTLV LLLIPGLIYG
210 220 230 240 250
KYLVHLSKKS FKEYTKANSI VEQALSSIKT ILSFTAETQI IKKYSEVLER
260 270 280 290 300
HKKLGLKQGL AKGLAVGSSG ISFTIWAFLA WYGSRLVMHK QETGGRIYAA
310 320 330 340 350
GISFVLGGIS LGTALTEIRY FSEASVAAAR ICSRIDRISE IDGEDTKKGF
360 370 380 390 400
IPGEKMKGRV EFERVTLVYL SRPETIILKD FTLTVDVGQS VALMGASGSG
410 420 430 440 450
KSTVIALLQR FYDPCEGFVR IDGFDIKTLQ LKWMRQHIGV VSQDHALFGT
460 470 480 490 500
SIMENLMFGK NKASMDEVIS AAKAANAHGF ITQLPNGYDT HIGNRGALLS
510 520 530 540 550
GGQKQRIAIA RAIIRNPVIL LLDEATSALD GESETLIQNA LDQVAAGRTT
560 570 580 590 600
LVVAHKLSTV RGANIIAMLE NGSVRELGSH EDLMTKNNHY AKLVKLQRQF
610 620 630 640 650
GHEHQQDLQD RVNSPEIQQR WSTMNSVIRL SNRSSPDLIV SPITLESNHT
660 670 680 690 700
TKINENIPST SFTRLLPFVS PEWKSSLVGC ISATTFGAIQ PVYALSIGGM
710 720 730 740 750
ISAFFAKSSQ EMQDKIHIYS LIFISLTFLS ITLNLLQHYS FAKMGERLMQ
760 770 780 790 800
RLRLKMLEKI FTFEPAWFDV EENFTSEICS RLNNEVSIVK SLVADRISLL
810 820 830 840 850
VQTISGVTIA MIIGLLISWK LALVMIAVQP LSILCFYTKK VLLSKISNNY
860 870 880 890 900
AYAQNRSSQI ASEAIYNHKI VTSLGSTKKI IEIFDNAQYE AKRKGRKAAW
910 920 930 940 950
LAGFGMGSAQ CLTFLTWALD FWYGGVLVQK GEISAGDVFK TFFVLVSTGK
960 970 980 990 1000
VIAEAGSMTS DLAKGTAAIS SVFNILDRPS SHENTNHGEK MGTIQGRIEL
1010 1020 1030 1040 1050
KNIDFSYPNR PSILVLRDFS LDIKPGTSIG LVGTSGCGKS TVIALIQRFY
1060 1070 1080 1090 1100
DVEIGCVKID SENLRDINIK WYRKHTALVS QEPVVYSGSI QDNIILGRPE
1110 1120 1130 1140 1150
ATEDEVVEAA KAANAHDFIS AMEKGYKTEC GERGVQLSGG QKQRIAIARA
1160 1170 1180 1190 1200
FLRSPIILLL DEVTSSLDSN SEQEVQDALA RIMASRNMTT VVVAHRLNTL
1210 1220 1230 1240
KNLDCIALIV DGTVIETGSY DHLKNIGGQF SRLAHAHDLK S
Length:1,241
Mass (Da):137,112
Last modified:October 1, 2000 - v1
Checksum:iDD3367D1E7F07D28
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002043 Genomic DNA. Translation: BAB02613.1.
CP002686 Genomic DNA. No translation available.

Similar proteinsi

Entry informationi

Entry nameiAB8B_ARATH
AccessioniPrimary (citable) accession number: Q9LHK4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: October 1, 2000
Last modified: October 25, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families