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Q9LHJ9

- P2C38_ARATH

UniProt

Q9LHJ9 - P2C38_ARATH

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Protein
Probable protein phosphatase 2C 38
Gene
At3g12620, MMF12.6, T2E22.7
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi88 – 881Manganese 1 By similarity
Metal bindingi88 – 881Manganese 2 By similarity
Metal bindingi89 – 891Manganese 1; via carbonyl oxygen By similarity
Metal bindingi289 – 2891Manganese 2 By similarity
Metal bindingi348 – 3481Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT3G12620-MONOMER.
ARA:GQT-2668-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 38 (EC:3.1.3.16)
Short name:
AtPP2C38
Gene namesi
Ordered Locus Names:At3g12620
ORF Names:MMF12.6, T2E22.7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 3

Organism-specific databases

TAIRiAT3G12620.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 385385Probable protein phosphatase 2C 38
PRO_0000367963Add
BLAST

Proteomic databases

PaxDbiQ9LHJ9.
PRIDEiQ9LHJ9.

Expressioni

Gene expression databases

GenevestigatoriQ9LHJ9.

Interactioni

Protein-protein interaction databases

BioGridi5776. 3 interactions.
IntActiQ9LHJ9. 3 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ9LHJ9.
SMRiQ9LHJ9. Positions 73-362.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini83 – 329247PP2C-like
Add
BLAST

Sequence similaritiesi

Belongs to the PP2C family.
Contains 1 PP2C-like domain.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000238703.
InParanoidiQ9LHJ9.
OMAiRSLHPND.
PhylomeDBiQ9LHJ9.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LHJ9-1 [UniParc]FASTAAdd to Basket

« Hide

MVSSATILRM VAPCWRRPSV KGDHSTRDAN GRCDGLLWYK DSGNHVAGEF    50
SMSVIQANNL LEDHSKLESG PVSMFDSGPQ ATFVGVYDGH GGPEAARFVN 100
KHLFDNIRKF TSENHGMSAN VITKAFLATE EDFLSLVRRQ WQIKPQIASV 150
GACCLVGIIC SGLLYIANAG DSRVVLGRLE KAFKIVKAVQ LSSEHNASLE 200
SVREELRSLH PNDPQIVVLK HKVWRVKGII QVSRSIGDAY LKKAEFNREP 250
LLAKFRVPEV FHKPILRAEP AITVHKIHPE DQFLIFASDG LWEHLSNQEA 300
VDIVNTCPRN GIARKLIKTA LREAAKKREM RYSDLKKIDR GVRRHFHDDI 350
TVIVVFLDSH LVSRSTSRRP LLSISGGGDL AGPST 385
Length:385
Mass (Da):42,851
Last modified:October 1, 2000 - v1
Checksum:i72F7C983DB972D48
GO

Sequence cautioni

The sequence AAG51012.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC069474 Genomic DNA. Translation: AAG51012.1. Different initiation.
AP002044 Genomic DNA. Translation: BAB02253.1.
CP002686 Genomic DNA. Translation: AEE75224.1.
CP002686 Genomic DNA. Translation: AEE75225.1.
BT004824 mRNA. Translation: AAO44090.1.
AK317334 mRNA. Translation: BAH20008.1.
AK317402 mRNA. Translation: BAH20072.1.
AK227879 mRNA. Translation: BAE99854.1.
RefSeqiNP_001030682.1. NM_001035605.1.
NP_187868.2. NM_112097.4.
UniGeneiAt.27990.

Genome annotation databases

EnsemblPlantsiAT3G12620.1; AT3G12620.1; AT3G12620.
AT3G12620.2; AT3G12620.2; AT3G12620.
GeneIDi820442.
KEGGiath:AT3G12620.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC069474 Genomic DNA. Translation: AAG51012.1 . Different initiation.
AP002044 Genomic DNA. Translation: BAB02253.1 .
CP002686 Genomic DNA. Translation: AEE75224.1 .
CP002686 Genomic DNA. Translation: AEE75225.1 .
BT004824 mRNA. Translation: AAO44090.1 .
AK317334 mRNA. Translation: BAH20008.1 .
AK317402 mRNA. Translation: BAH20072.1 .
AK227879 mRNA. Translation: BAE99854.1 .
RefSeqi NP_001030682.1. NM_001035605.1.
NP_187868.2. NM_112097.4.
UniGenei At.27990.

3D structure databases

ProteinModelPortali Q9LHJ9.
SMRi Q9LHJ9. Positions 73-362.
ModBasei Search...

Protein-protein interaction databases

BioGridi 5776. 3 interactions.
IntActi Q9LHJ9. 3 interactions.

Proteomic databases

PaxDbi Q9LHJ9.
PRIDEi Q9LHJ9.

Protocols and materials databases

DNASUi 820442.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT3G12620.1 ; AT3G12620.1 ; AT3G12620 .
AT3G12620.2 ; AT3G12620.2 ; AT3G12620 .
GeneIDi 820442.
KEGGi ath:AT3G12620.

Organism-specific databases

TAIRi AT3G12620.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000238703.
InParanoidi Q9LHJ9.
OMAi RSLHPND.
PhylomeDBi Q9LHJ9.

Enzyme and pathway databases

BioCyci ARA:AT3G12620-MONOMER.
ARA:GQT-2668-MONOMER.

Gene expression databases

Genevestigatori Q9LHJ9.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
    Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.
    , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
    Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.
    DNA Res. 7:217-221(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
    Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
    DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  6. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  7. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C38_ARATH
AccessioniPrimary (citable) accession number: Q9LHJ9
Secondary accession number(s): Q9C7B3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi