ID   LNK3_ARATH              Reviewed;         269 AA.
AC   Q9LHH5;
DT   13-APR-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   27-MAR-2024, entry version 125.
DE   RecName: Full=Protein LNK3 {ECO:0000303|PubMed:23818596};
DE   AltName: Full=Night light-inducible and clock-regulated 3 {ECO:0000303|PubMed:23818596};
GN   Name=LNK3 {ECO:0000303|PubMed:23818596};
GN   OrderedLocusNames=At3g12320 {ECO:0000312|Araport:AT3G12320};
GN   ORFNames=F28J15.9 {ECO:0000312|EMBL:AAG51066.1}, T2E22.34
GN   {ECO:0000312|EMBL:AAG51013.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|EMBL:BAB03140.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130713; DOI=10.1038/35048706;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA   Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA   Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA   Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA   Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA   Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA   Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA   Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [5]
RP   INDUCTION, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=23818596; DOI=10.1073/pnas.1302170110;
RA   Rugnone M.L., Faigon Soverna A., Sanchez S.E., Schlaen R.G., Hernando C.E.,
RA   Seymour D.K., Mancini E., Chernomoretz A., Weigel D., Mas P.,
RA   Yanovsky M.J.;
RT   "LNK genes integrate light and clock signaling networks at the core of the
RT   Arabidopsis oscillator.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:12120-12125(2013).
RN   [6]
RP   DISRUPTION PHENOTYPE.
RX   PubMed=25012192; DOI=10.1105/tpc.114.126573;
RA   Xie Q., Wang P., Liu X., Yuan L., Wang L., Zhang C., Li Y., Xing H.,
RA   Zhi L., Yue Z., Zhao C., McClung C.R., Xu X.;
RT   "LNK1 and LNK2 are transcriptional coactivators in the Arabidopsis
RT   circadian oscillator.";
RL   Plant Cell 26:2843-2857(2014).
RN   [7]
RP   INTERACTION WITH RVE8.
RX   PubMed=25848001; DOI=10.1073/pnas.1420792112;
RA   Perez-Garcia P., Ma Y., Yanovsky M.J., Mas P.;
RT   "Time-dependent sequestration of RVE8 by LNK proteins shapes the diurnal
RT   oscillation of anthocyanin biosynthesis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 112:5249-5253(2015).
CC   -!- FUNCTION: Probable transcriptional coactivator.
CC       {ECO:0000250|UniProtKB:A8MQN2}.
CC   -!- SUBUNIT: Interacts with REV8. {ECO:0000269|PubMed:25848001}.
CC   -!- INDUCTION: Repressed by members of the TOC1/PRR1 family of clock genes.
CC       {ECO:0000269|PubMed:23818596}.
CC   -!- DISRUPTION PHENOTYPE: No effect on circadian clock.
CC       {ECO:0000269|PubMed:25012192}.
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DR   EMBL; AP002047; BAB03140.1; -; Genomic_DNA.
DR   EMBL; AC069472; AAG51066.1; -; Genomic_DNA.
DR   EMBL; AC069474; AAG51013.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE75183.1; -; Genomic_DNA.
DR   EMBL; CP002686; ANM64652.1; -; Genomic_DNA.
DR   EMBL; AF360337; AAK28634.1; -; mRNA.
DR   EMBL; AY051074; AAK93751.1; -; mRNA.
DR   RefSeq; NP_001326665.1; NM_001337987.1.
DR   RefSeq; NP_566419.1; NM_112067.4.
DR   AlphaFoldDB; Q9LHH5; -.
DR   STRING; 3702.Q9LHH5; -.
DR   iPTMnet; Q9LHH5; -.
DR   PaxDb; 3702-AT3G12320-1; -.
DR   ProteomicsDB; 238476; -.
DR   EnsemblPlants; AT3G12320.1; AT3G12320.1; AT3G12320.
DR   EnsemblPlants; AT3G12320.3; AT3G12320.3; AT3G12320.
DR   GeneID; 820411; -.
DR   Gramene; AT3G12320.1; AT3G12320.1; AT3G12320.
DR   Gramene; AT3G12320.3; AT3G12320.3; AT3G12320.
DR   KEGG; ath:AT3G12320; -.
DR   Araport; AT3G12320; -.
DR   TAIR; AT3G12320; LNK3.
DR   eggNOG; ENOG502R7JN; Eukaryota.
DR   HOGENOM; CLU_954267_0_0_1; -.
DR   InParanoid; Q9LHH5; -.
DR   OMA; YRSDGMW; -.
DR   OrthoDB; 443592at2759; -.
DR   PhylomeDB; Q9LHH5; -.
DR   PRO; PR:Q9LHH5; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LHH5; baseline and differential.
DR   GO; GO:0007623; P:circadian rhythm; IEP:TAIR.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   InterPro; IPR039928; LNK.
DR   PANTHER; PTHR33334; PROTEIN LNK1; 1.
DR   PANTHER; PTHR33334:SF15; PROTEIN LNK3; 1.
PE   1: Evidence at protein level;
KW   Activator; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..269
FT                   /note="Protein LNK3"
FT                   /id="PRO_0000436033"
SQ   SEQUENCE   269 AA;  30554 MW;  52F0D62365FEEE34 CRC64;
     MDCYAEELVV PNYQESSSET YPSTGMWGGW SMSSPEAAEK CFDYDGFNGE GMMYSQMSMR
     TSEEEEESKR SKAFYGASSL HDFEGIEQMD DMFLSSILED VPEDDGDVHR ATSSNNSVGS
     SSMYGGGREV PMFHCHDMSF KEEAPFTISD LSEENMLDSN YGDELSSEEF VLQDLQRASQ
     KLTDETRKCF RDTFYRLARS SQDKSDSVSP NSEELLMQTS RYDYGDGNRF SREEEIESET
     NSIDRAVANL TFNKMESNIS NFPLSERVQ
//