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Protein

ABC transporter B family member 15

Gene

ABCB15

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi394 – 4018ATP 1PROSITE-ProRule annotation
Nucleotide bindingi1030 – 10378ATP 2PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT3G28345-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter B family member 15
Short name:
ABC transporter ABCB.15
Short name:
AtABCB15
Alternative name(s):
Multidrug resistance protein 13
P-glycoprotein 15
Gene namesi
Name:ABCB15
Synonyms:MDR13, PGP15
Ordered Locus Names:At3g28345
ORF Names:MZF16.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G28345.

Subcellular locationi

  • Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei35 – 5521HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei82 – 10221HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei158 – 18023HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei184 – 20623HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei264 – 28421HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei296 – 31621HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei681 – 70121HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei714 – 73421HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei794 – 81320HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei817 – 83923HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei895 – 91521HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei923 – 94321HelicalPROSITE-ProRule annotationAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12401240ABC transporter B family member 15PRO_0000227924Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi542 – 5421N-linked (GlcNAc...)Sequence analysis
Glycosylationi605 – 6051N-linked (GlcNAc...)Sequence analysis
Glycosylationi622 – 6221N-linked (GlcNAc...)Sequence analysis
Glycosylationi646 – 6461N-linked (GlcNAc...)Sequence analysis
Glycosylationi769 – 7691N-linked (GlcNAc...)Sequence analysis
Glycosylationi1015 – 10151N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9LHD1.
PRIDEiQ9LHD1.

PTM databases

iPTMnetiQ9LHD1.

Expressioni

Gene expression databases

GenevisibleiQ9LHD1. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G28345.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LHD1.
SMRiQ9LHD1. Positions 19-598, 707-1237.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini35 – 324290ABC transmembrane type-1 1PROSITE-ProRule annotationAdd
BLAST
Domaini359 – 595237ABC transporter 1PROSITE-ProRule annotationAdd
BLAST
Domaini672 – 960289ABC transmembrane type-1 2PROSITE-ProRule annotationAdd
BLAST
Domaini995 – 1233239ABC transporter 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 ABC transmembrane type-1 domains.PROSITE-ProRule annotation
Contains 2 ABC transporter domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
InParanoidiQ9LHD1.
KOiK05658.
OMAiTFMQSIS.
PhylomeDBiQ9LHD1.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LHD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKEEEKESG RNKMNCFGSV RSIFMHADGV DWLLMGLGLI GAVGDGFTTP
60 70 80 90 100
LVLLITSKLM NNIGGSSFNT DTFMQSISKN SVALLYVACG SWVVCFLEGY
110 120 130 140 150
CWTRTGERQT ARMREKYLRA VLRQDVGYFD LHVTSTSDVI TSVSSDSFVI
160 170 180 190 200
QDVLSEKLPN FLMSASTFVG SYIVGFILLW RLAIVGLPFI VLLVIPGLMY
210 220 230 240 250
GRALISISRK IREEYNEAGF VAEQAISSVR TVYAFSGERK TISKFSTALQ
260 270 280 290 300
GSVKLGIKQG LAKGITIGSN GITFAMWGFM SWYGSRMVMY HGAQGGTVFA
310 320 330 340 350
VAAAIAIGGV SLGGGLSNLK YFFEAASVGE RIMEVINRVP KIDSDNPDGH
360 370 380 390 400
KLEKIRGEVE FKNVKFVYPS RLETSIFDDF CLRVPSGKTV ALVGGSGSGK
410 420 430 440 450
STVISLLQRF YDPLAGEILI DGVSIDKLQV KWLRSQMGLV SQEPALFATT
460 470 480 490 500
IKENILFGKE DASMDDVVEA AKASNAHNFI SQLPNGYETQ VGERGVQMSG
510 520 530 540 550
GQKQRIAIAR AIIKSPTILL LDEATSALDS ESERVVQEAL ENASIGRTTI
560 570 580 590 600
LIAHRLSTIR NADVISVVKN GHIVETGSHD ELMENIDGQY STLVHLQQIE
610 620 630 640 650
KQDINVSVKI GPISDPSKDI RNSSRVSTLS RSSSANSVTG PSTIKNLSED
660 670 680 690 700
NKPQLPSFKR LLAMNLPEWK QALYGCISAT LFGAIQPAYA YSLGSMVSVY
710 720 730 740 750
FLTSHDEIKE KTRIYALSFV GLAVLSFLIN ISQHYNFAYM GEYLTKRIRE
760 770 780 790 800
RMLSKVLTFE VGWFDRDENS SGAICSRLAK DANVVRSLVG DRMALVVQTV
810 820 830 840 850
SAVTIAFTMG LVIAWRLALV MIAVQPVIIV CFYTRRVLLK SMSKKAIKAQ
860 870 880 890 900
DESSKLAAEA VSNVRTITAF SSQERIMKML EKAQESPRRE SIRQSWFAGF
910 920 930 940 950
GLAMSQSLTS CTWALDFWYG GRLIQDGYIT AKALFETFMI LVSTGRVIAD
960 970 980 990 1000
AGSMTTDLAK GSDAVGSVFA VLDRYTSIDP EDPDGYETER ITGQVEFLDV
1010 1020 1030 1040 1050
DFSYPTRPDV IIFKNFSIKI EEGKSTAIVG PSGSGKSTII GLIERFYDPL
1060 1070 1080 1090 1100
KGIVKIDGRD IRSYHLRSLR RHIALVSQEP TLFAGTIREN IIYGGVSDKI
1110 1120 1130 1140 1150
DEAEIIEAAK AANAHDFITS LTEGYDTYCG DRGVQLSGGQ KQRIAIARAV
1160 1170 1180 1190 1200
LKNPSVLLLD EATSALDSQS ERVVQDALER VMVGRTSVVI AHRLSTIQNC
1210 1220 1230 1240
DAIAVLDKGK LVERGTHSSL LSKGPTGIYF SLVSLQTTSG
Length:1,240
Mass (Da):135,641
Last modified:October 1, 2000 - v1
Checksum:iF00F17EBD4709173
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002051, AB026644 Genomic DNA. Translation: BAB02627.1.
CP002686 Genomic DNA. Translation: AEE77436.1.
RefSeqiNP_189475.1. NM_113754.2.
UniGeneiAt.43730.

Genome annotation databases

EnsemblPlantsiAT3G28345.1; AT3G28345.1; AT3G28345.
GeneIDi822463.
GrameneiAT3G28345.1; AT3G28345.1; AT3G28345.
KEGGiath:AT3G28345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002051, AB026644 Genomic DNA. Translation: BAB02627.1.
CP002686 Genomic DNA. Translation: AEE77436.1.
RefSeqiNP_189475.1. NM_113754.2.
UniGeneiAt.43730.

3D structure databases

ProteinModelPortaliQ9LHD1.
SMRiQ9LHD1. Positions 19-598, 707-1237.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G28345.1.

PTM databases

iPTMnetiQ9LHD1.

Proteomic databases

PaxDbiQ9LHD1.
PRIDEiQ9LHD1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G28345.1; AT3G28345.1; AT3G28345.
GeneIDi822463.
GrameneiAT3G28345.1; AT3G28345.1; AT3G28345.
KEGGiath:AT3G28345.

Organism-specific databases

TAIRiAT3G28345.

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
InParanoidiQ9LHD1.
KOiK05658.
OMAiTFMQSIS.
PhylomeDBiQ9LHD1.

Enzyme and pathway databases

BioCyciARA:AT3G28345-MONOMER.

Miscellaneous databases

PROiQ9LHD1.

Gene expression databases

GenevisibleiQ9LHD1. AT.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
    Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.
    DNA Res. 7:217-221(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
    Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
    DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "The Arabidopsis thaliana ABC protein superfamily, a complete inventory."
    Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.
    J. Biol. Chem. 276:30231-30244(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.
  5. Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiAB15B_ARATH
AccessioniPrimary (citable) accession number: Q9LHD1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: October 1, 2000
Last modified: February 17, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.