Q9LGR0 (SSP1A_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
FACT complex subunit SSRP1-A

Alternative name(s):
Early drought-induced protein R1G1A
Facilitates chromatin transcription complex subunit SSRP1-A
Recombination signal sequence recognition protein 1-A

Gene names

Name:	SSRP1-A
Synonyms:	R1G1A
Ordered Locus Names:	Os01g0184900, LOC_Os01g08970
ORF Names:	P0510F03.10

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	641 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Binds specifically to double-stranded DNA By similarity.
Subunit structure	Component of the FACT complex, a stable heterodimer of SPT16 and SSRP1 By similarity.
Subcellular location	Nucleus By similarity. Chromosome By similarity.
Sequence similarities	Belongs to the SSRP1 family. Contains 1 HMG box DNA-binding domain.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication Transcription Transcription regulation
Cellular component	Chromosome Nucleus
Ligand	DNA-binding
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chromosome Inferred from electronic annotation. Source: UniProtKB-SubCell nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 641	641	FACT complex subunit SSRP1-A		PRO_0000245196
Regions
	DNA binding	556 – 624	69	HMG box
	Compositional bias	458 – 507	50	Asp-rich (acidic)
	Compositional bias	515 – 551	37	Lys-rich (basic)
Experimental info
	Sequence conflict	543	1	D → E in AAM46895. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q9LGR0 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 746162D9ED3BF7AD	FASTA	641	71,334
	10 20 30 40 50 60 MTDGHLFNNI LLGGRAGSNP GQFKVYSGGL AWKRQGGGKT IEIEKSDLTS VTWMKVPRAY 70 80 90 100 110 120 QLGVRTKDGL FYKFIGFREQ DVSSLTNFMQ KNMGLSPDEK QLSVSGQNWG GIDINGNMLT 130 140 150 160 170 180 FMVGSKQAFE VSLADVSQTQ MQGKTDVLLE FHVDDTTGGN EKDSLMDLSF HVPTSNTQFL 190 200 210 220 230 240 GDENRTAAQV LWETIMGVAD VDSSEEAVVT FEGIAILTPR GRYSVELHLS FLRLQGQAND 250 260 270 280 290 300 FKIQYSSIVR LFLLPKSNNP HTFVVVTLDP PIRKGQTLYP HIVIQFETEA VVERNLALTK 310 320 330 340 350 360 EVLAEKYKDR LEESYKGLIH EVFTKVLRGL SGAKVTRPGS FRSCQDGYAV KSSLKAEDGL 370 380 390 400 410 420 LYPLEKGFFF LPKPPTLILH EEIEFVEFER HGAGGASISS HYFDLLVKLK NDQEHLFRNI 430 440 450 460 470 480 QRSEYHNLFN FINGKHLKIM NLGDGQGATG GVTAVLRDTD DDAVDPHLER IKNQAGDEES 490 500 510 520 530 540 DEEDEDFVAD KDDSGSPTDD SGGEDSDASE SGGEKEKLSK KEASSSKPPV KRKPKGRDEE 550 560 570 580 590 600 GSDKRKPKKK KDPNAPKRAM TPFMYFSMAE RGNMKNNNPD LPTTEIAKKL GEMWQKMTGE 610 620 630 640 EKQPYIQQSQ VDKKRYEKES AVYRGAAAMD VDSGSGGNES D

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of early drought-induced cDNAs in rice." Klueva N., Tyagi A., Zhang J., Zheng H., Nguyen H. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T. Nature 420:312-316(2002) [PubMed: 12447438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF503585 mRNA. Translation: AAM46895.1. AP002486 Genomic DNA. Translation: BAB03358.1.
RefSeq	NP_001042237.1. NM_001048772.1.
UniGene	Os.7840.
3D structure databases
ProteinModelPortal	Q9LGR0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4325652.
KEGG	osa:4325652.
NMPDR	fig|39947.1.peg.6562.
Organism-specific databases
Gramene	Q9LGR0.
Phylogenomic databases
OMA	CSLKASE.
PhylomeDB	Q9LGR0.
ProtClustDB	CLSN2684068.
Family and domain databases
InterPro	IPR000910. HMG_HMG1/HMG2. IPR009071. HMG_superfamily. IPR000969. SSrcognition. [Graphical view]
Gene3D	G3DSA:1.10.30.10. HMG-box. 1 hit.
KO	K09272.
Pfam	PF00505. HMG_box. 1 hit. PF03531. SSrecog. 1 hit. [Graphical view]
PRINTS	PR00887. SSRCOGNITION.
SMART	SM00398. HMG. 1 hit. [Graphical view]
SUPFAM	SSF47095. HMG-box. 1 hit.
PROSITE	PS50118. HMG_BOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SSP1A_ORYSJ

Accession

Primary (citable) accession number: Q9LGR0
Secondary accession number(s): Q8LKS8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2006
Last sequence update:	October 1, 2000
Last modified:	November 16, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program