Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9LG11 (HAC4_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Histone acetyltransferase HAC4

EC=2.3.1.48
Gene names
Name:HAC4
Synonyms:PCAT3
Ordered Locus Names:At1g55970
ORF Names:F14J16.27, T6H22.22
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length1470 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation By similarity.

Catalytic activity

Acetyl-CoA + [histone] = CoA + acetyl-[histone].

Subcellular location

Nucleus Probable.

Tissue specificity

Rosette leaves, stems and flowers. Ref.5

Developmental stage

Expressed in young seedlings. Ref.5

Sequence similarities

Contains 1 PHD-type zinc finger.

Contains 2 TAZ-type zinc fingers.

Contains 2 ZZ-type zinc fingers.

Sequence caution

The sequence AAF02849.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence AAF79331.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence AAK73519.1 differs from that shown. Reason: Frameshift at position 988.

The sequence AEE33326.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 14701470Histone acetyltransferase HAC4
PRO_0000269742

Regions

Zinc finger416 – 49580TAZ-type 1
Zinc finger764 – 84178PHD-type
Zinc finger1174 – 122148ZZ-type 1
Zinc finger1294 – 134148ZZ-type 2
Zinc finger1358 – 143679TAZ-type 2
Compositional bias54 – 8734Gln-rich
Compositional bias323 – 39573Gln-rich

Sequences

Sequence LengthMass (Da)Tools
Q9LG11 [UniParc].

Last modified January 9, 2007. Version 2.
Checksum: C1583E17D19C06CD

FASTA1,470166,802
        10         20         30         40         50         60 
MNNNKEVPQN SVAVSSSSSA PITVISPQQD ANNFIKKRRT ALRNRIYAIV RHKQKQHQIF 

        70         80         90        100        110        120 
LDKKNQQQQQ RVDDATQRAL LEKQDQQCIA ATRMIEEELL KSSRSFEEYF DLRTFDARVR 

       130        140        150        160        170        180 
TILQQLGTML SQRRAAAAAM NNGEAQCITS TRAVHTSISV SNSFQCGRSL VPINCTTATA 

       190        200        210        220        230        240 
GAFSIGPDMQ THHSTGANHQ MVEVNRPNMN QITCGISSPL ITGFNGNCVP VSANIPMTSQ 

       250        260        270        280        290        300 
DLFNATHFST LPQPFLQPPP DQSHMHRYSM SNVASFGQSN PYPCGVVMSS GSMAVAQNSI 

       310        320        330        340        350        360 
PWNNPNPMQG LDPTVTSYHS NLQPMQQTPL PKRQLHHPLW NTNFQSAPNN RDNLPQVSQQ 

       370        380        390        400        410        420 
LSNHGSRQHR GQHSQNLYPG QLQNQDRLLP NLTQQAMALA APVMHVPSKQ VNEDCGQTSS 

       430        440        450        460        470        480 
NTVLRWIPFM FHARHCKAKK DKCASKFCFQ ARKIVKHIDC CKVPNCKYRY CLGTRMWLDH 

       490        500        510        520        530        540 
FKQCKSISCR TCVAVREYME KNKYTIVPLR RAKCSSASSK CQPKKSSKSR QAYKKGGAEA 

       550        560        570        580        590        600 
PSVDADLQRS IKRPKLHRPS QNITPETKSI SVTGCGVVCK PHSLMNMQEK DGLQSLKVEA 

       610        620        630        640        650        660 
MPMDIDVPGA SEIPVTRELV KHVAEDTPKG NNCGGFAMVE KTSCLLAQGK SKCMNEMSAP 

       670        680        690        700        710        720 
KEENVKQSVE VVDASKMEIS SLVELFTPEQ VKEHIRSLRQ WVGQSKTKAE KNKAMGCSMS 

       730        740        750        760        770        780 
VNSCQLCAVE WLVFEPVPIY CSPCGIRIKK NALHYSIAVG ESRHYVCAPC YNEAREKLVF 

       790        800        810        820        830        840 
LDGTSIPKTR LQKKKNDEQV PEGWVQCDKC EAWQHIICAL FNSRRNHGES TKYTCPSCYI 

       850        860        870        880        890        900 
QEVEQRERRP LPLSAVPGAT SLPVTSLSKH LEERLFKKLK EERQERARLQ GKTYEEVPGA 

       910        920        930        940        950        960 
ESLTVRVVAS VDKVLEVKER FLELFREENY PSEFPYKSKA IFLFQKIENV EVCLFGMFVQ 

       970        980        990       1000       1010       1020 
EFGTDSGPPN ERRVYLSYLD SVKYFRPTFR TVSGEALRTF VYHEILIGYL DYCKKRGFTS 

      1030       1040       1050       1060       1070       1080 
CYIWACPPLK GDDYILYCHP EIQKTPKTDK LREWYLAMLR KASKEDVVVE CTNLYNHFFV 

      1090       1100       1110       1120       1130       1140 
QSGECRANVT AARLPYFDGD YWPSAAEDLL RQMNQEDDGE TKLHRKGLTK KVISKRALKA 

      1150       1160       1170       1180       1190       1200 
VGQLDLSLNA SKDRLMMQKL GETICPMKED FIMVHLQHCC KHCTTLMVSG NRWVCNHCKN 

      1210       1220       1230       1240       1250       1260 
FQICDKCYEV EQNRINIERH PINQKEKHAL FPVAIKDVPT KIEDKDNNLE SEFFHNRQAF 

      1270       1280       1290       1300       1310       1320 
LNLCQGNNYQ YETLRRAKHS SMMILYHLHN PTAPAFATVC TICQQEVENS QGWHCEVCPG 

      1330       1340       1350       1360       1370       1380 
YDVCSACYSK DSINHSHKLT SRSSSTDSTV VQQNGQASQS YQVKLEKLKK LLVHAATCRS 

      1390       1400       1410       1420       1430       1440 
TQCQYQGCRK SKMLFRHCID CTTGDCPICK GLWSLLKLHA RNCRDSKCTV PKCSGLRAIS 

      1450       1460       1470 
RRKQQQADKR RRAAVMEMMR ERAAEATRTG 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes."
Pandey R., Mueller A., Napoli C.A., Selinger D.A., Pikaard C.S., Richards E.J., Bender J., Mount D.W., Jorgensen R.A.
Nucleic Acids Res. 30:5036-5055(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 10-760 AND 1086-1470, NOMENCLATURE.
[4]Richards E.J.
Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 772-1470.
[5]"Plant orthologs of p300/CBP: conservation of a core domain in metazoan p300/CBP acetyltransferase-related proteins."
Bordoli L., Netsch M., Luethi U., Lutz W., Eckner R.
Nucleic Acids Res. 29:589-597(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: DEVELOPMENTAL STAGE, TISSUE SPECIFICITY.

Web resources

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC002304 Genomic DNA. Translation: AAF79331.1. Sequence problems.
AC009894 Genomic DNA. Translation: AAF02849.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE33326.1. Sequence problems.
AF512559 mRNA. Translation: AAM34789.1.
AF512560 mRNA. Translation: AAM34790.1.
AF389513 mRNA. Translation: AAK73519.1. Frameshift.
RefSeqNP_564706.1. NM_104475.2.
UniGeneAt.26162.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID842048.
KEGGath:AT1G55970.

Organism-specific databases

TAIRAT1G55970.

Phylogenomic databases

eggNOGNOG257281.
InParanoidQ9LG11.
KOK04498.
PhylomeDBQ9LG11.

Enzyme and pathway databases

BioCycARA:AT1G55970-MONOMER.

Gene expression databases

GenevestigatorQ9LG11.

Family and domain databases

Gene3D1.20.1020.10. 2 hits.
3.30.40.10. 1 hit.
InterProIPR013178. Histone_H3-K56_AcTrfase_RTT109.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
IPR000197. Znf_TAZ.
IPR000433. Znf_ZZ.
[Graphical view]
PfamPF08214. KAT11. 1 hit.
PF00628. PHD. 1 hit.
PF02135. zf-TAZ. 2 hits.
PF00569. ZZ. 1 hit.
[Graphical view]
SMARTSM00249. PHD. 1 hit.
SM00551. ZnF_TAZ. 2 hits.
SM00291. ZnF_ZZ. 2 hits.
[Graphical view]
SUPFAMSSF57903. SSF57903. 1 hit.
SSF57933. SSF57933. 2 hits.
PROSITEPS01359. ZF_PHD_1. 1 hit.
PS50134. ZF_TAZ. 2 hits.
PS01357. ZF_ZZ_1. 2 hits.
PS50135. ZF_ZZ_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHAC4_ARATH
AccessionPrimary (citable) accession number: Q9LG11
Secondary accession number(s): F4I3I0 expand/collapse secondary AC list , Q8LRK3, Q8LRK4, Q94EW2, Q9SGS6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: January 9, 2007
Last modified: April 16, 2014
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names