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Protein

UDP-glycosyltransferase 78D2

Gene

UGT78D2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes the glycosylation of flavonoids from UDP-glucose. Catalyzes the glycosylation of anthocyanins from UDP-glucose. Possesses high quercetin 3-O-glucosyltransferase activity in vitro. Also active in vitro on benzoates and benzoate derivatives.4 Publications

Catalytic activityi

UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.

Pathwayi: flavonoid biosynthesis

This protein is involved in the pathway flavonoid biosynthesis, which is part of Secondary metabolite biosynthesis.
View all proteins of this organism that are known to be involved in the pathway flavonoid biosynthesis and in Secondary metabolite biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei286UDP-glucoseBy similarity1

GO - Molecular functioni

GO - Biological processi

  • flavonoid biosynthetic process Source: UniProtKB-UniPathway
  • phenylpropanoid metabolic process Source: UniProtKB-KW
  • response to karrikin Source: TAIR

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processPhenylpropanoid metabolism

Enzyme and pathway databases

BioCyciARA:AT5G17050-MONOMER
MetaCyc:AT5G17050-MONOMER
UniPathwayiUPA00154

Protein family/group databases

CAZyiGT1 Glycosyltransferase Family 1

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glycosyltransferase 78D2 (EC:2.4.1.-)
Alternative name(s):
Anthocyanin 3-O-glucosyltransferase
Flavonol 3-O-glucosyltransferase (EC:2.4.1.91)
UDP glucose:flavonoid 3-O-glucosyltransferase
Gene namesi
Name:UGT78D2
Synonyms:AGT
Ordered Locus Names:At5g17050
ORF Names:F2K13.200
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G17050
TAIRilocus:2148126 AT5G17050

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002852751 – 460UDP-glycosyltransferase 78D2Add BLAST460

Proteomic databases

PaxDbiQ9LFJ8
PRIDEiQ9LFJ8

PTM databases

iPTMnetiQ9LFJ8

Expressioni

Inductioni

By PAP1.1 Publication

Gene expression databases

ExpressionAtlasiQ9LFJ8 baseline and differential
GenevisibleiQ9LFJ8 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G17050.1

Structurei

3D structure databases

ProteinModelPortaliQ9LFJ8
SMRiQ9LFJ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni339 – 341UDP-glucose bindingBy similarity3
Regioni356 – 364UDP-glucose bindingBy similarity9
Regioni378 – 381UDP-glucose bindingBy similarity4

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.Curated

Phylogenomic databases

eggNOGiKOG1192 Eukaryota
COG1819 LUCA
HOGENOMiHOG000237564
InParanoidiQ9LFJ8
KOiK10757
OMAiVEVVWEI
OrthoDBiEOG09360BMW
PhylomeDBiQ9LFJ8

Family and domain databases

InterProiView protein in InterPro
IPR002213 UDP_glucos_trans
IPR035595 UDP_glycos_trans_CS
PfamiView protein in Pfam
PF00201 UDPGT, 1 hit
PROSITEiView protein in PROSITE
PS00375 UDPGT, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LFJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKPSDPTRD SHVAVLAFPF GTHAAPLLTV TRRLASASPS TVFSFFNTAQ
60 70 80 90 100
SNSSLFSSGD EADRPANIRV YDIADGVPEG YVFSGRPQEA IELFLQAAPE
110 120 130 140 150
NFRREIAKAE TEVGTEVKCL MTDAFFWFAA DMATEINASW IAFWTAGANS
160 170 180 190 200
LSAHLYTDLI RETIGVKEVG ERMEETIGVI SGMEKIRVKD TPEGVVFGNL
210 220 230 240 250
DSVFSKMLHQ MGLALPRATA VFINSFEDLD PTLTNNLRSR FKRYLNIGPL
260 270 280 290 300
GLLSSTLQQL VQDPHGCLAW MEKRSSGSVA YISFGTVMTP PPGELAAIAE
310 320 330 340 350
GLESSKVPFV WSLKEKSLVQ LPKGFLDRTR EQGIVVPWAP QVELLKHEAT
360 370 380 390 400
GVFVTHCGWN SVLESVSGGV PMICRPFFGD QRLNGRAVEV VWEIGMTIIN
410 420 430 440 450
GVFTKDGFEK CLDKVLVQDD GKKMKCNAKK LKELAYEAVS SKGRSSENFR
460
GLLDAVVNII
Length:460
Mass (Da):50,486
Last modified:October 1, 2000 - v1
Checksum:iE9DEAD19E4E05188
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL391141 Genomic DNA Translation: CAC01718.1
CP002688 Genomic DNA Translation: AED92377.1
AY072325 mRNA Translation: AAL61932.1
AY128739 mRNA Translation: AAM91139.1
PIRiT51560
RefSeqiNP_197207.1, NM_121711.5
UniGeneiAt.27563

Genome annotation databases

EnsemblPlantsiAT5G17050.1; AT5G17050.1; AT5G17050
GeneIDi831568
GrameneiAT5G17050.1; AT5G17050.1; AT5G17050
KEGGiath:AT5G17050

Similar proteinsi

Entry informationi

Entry nameiU78D2_ARATH
AccessioniPrimary (citable) accession number: Q9LFJ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

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