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Protein

Protein NRT1/ PTR FAMILY 8.2

Gene

NPF8.2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Peptide transporter. Mediates the transport of di- and tripeptides. High affinity transporter. Involved in the uptake of peptides during pollen germination and tube growth.1 Publication

GO - Molecular functioni

  • dipeptide transporter activity Source: TAIR
  • transmembrane transporter activity Source: InterPro

GO - Biological processi

  • dipeptide transport Source: TAIR
  • pollen tube growth Source: TAIR
  • protein transport Source: UniProtKB-KW

Keywordsi

Biological processPeptide transport, Protein transport, Transport

Enzyme and pathway databases

BRENDAi3.6.3.43 399
ReactomeiR-ATH-427975 Proton/oligopeptide cotransporters
R-ATH-6798695 Neutrophil degranulation

Protein family/group databases

TCDBi2.A.17.3.8 the proton-dependent oligopeptide transporter (pot/ptr) family

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NRT1/ PTR FAMILY 8.2
Short name:
AtNPF8.2
Alternative name(s):
Peptide transporter PTR5
Gene namesi
Name:NPF8.2
Synonyms:PTR5
Ordered Locus Names:At5g01180
ORF Names:F7J8.160
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G01180
TAIRilocus:2150124 AT5G01180

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Transmembranei136 – 156HelicalSequence analysisAdd BLAST21
Transmembranei182 – 202HelicalSequence analysisAdd BLAST21
Transmembranei210 – 230HelicalSequence analysisAdd BLAST21
Transmembranei335 – 355HelicalSequence analysisAdd BLAST21
Transmembranei370 – 390HelicalSequence analysisAdd BLAST21
Transmembranei414 – 434HelicalSequence analysisAdd BLAST21
Transmembranei454 – 474HelicalSequence analysisAdd BLAST21
Transmembranei493 – 513HelicalSequence analysisAdd BLAST21
Transmembranei537 – 557HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

No visible phenotype.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003783231 – 570Protein NRT1/ PTR FAMILY 8.2Add BLAST570

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei99PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9LFB8

Expressioni

Tissue specificityi

Expressed in developing and germinating pollen grains and ovules.2 Publications

Developmental stagei

Expressed during early seed development.1 Publication

Gene expression databases

ExpressionAtlasiQ9LFB8 baseline and differential
GenevisibleiQ9LFB8 AT

Interactioni

Protein-protein interaction databases

BioGridi17001, 25 interactors
STRINGi3702.AT5G01180.1

Structurei

3D structure databases

ProteinModelPortaliQ9LFB8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1237 Eukaryota
COG3104 LUCA
HOGENOMiHOG000237400
InParanoidiQ9LFB8
OMAiRSMCMAL
OrthoDBiEOG093606MH
PhylomeDBiQ9LFB8

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR000109 POT_fam
IPR018456 PTR2_symporter_CS
PANTHERiPTHR11654 PTHR11654, 1 hit
PfamiView protein in Pfam
PF00854 PTR2, 1 hit
SUPFAMiSSF103473 SSF103473, 2 hits
PROSITEiView protein in PROSITE
PS01022 PTR2_1, 1 hit
PS01023 PTR2_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LFB8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDDKDIYTK DGTLDIHKKP ANKNKTGTWK ACRFILGTEC CERLAYYGMS
60 70 80 90 100
TNLINYLEKQ MNMENVSASK SVSNWSGTCY ATPLIGAFIA DAYLGRYWTI
110 120 130 140 150
ASFVVIYIAG MTLLTISASV PGLTPTCSGE TCHATAGQTA ITFIALYLIA
160 170 180 190 200
LGTGGIKPCV SSFGADQFDD TDEKEKESKS SFFNWFYFVI NVGAMIASSV
210 220 230 240 250
LVWIQMNVGW GWGLGVPTVA MAIAVVFFFA GSNFYRLQKP GGSPLTRMLQ
260 270 280 290 300
VIVASCRKSK VKIPEDESLL YENQDAESSI IGSRKLEHTK ILTFFDKAAV
310 320 330 340 350
ETESDNKGAA KSSSWKLCTV TQVEELKALI RLLPIWATGI VFASVYSQMG
360 370 380 390 400
TVFVLQGNTL DQHMGPNFKI PSASLSLFDT LSVLFWAPVY DKLIVPFARK
410 420 430 440 450
YTGHERGFTQ LQRIGIGLVI SIFSMVSAGI LEVARLNYVQ THNLYNEETI
460 470 480 490 500
PMTIFWQVPQ YFLVGCAEVF TFIGQLEFFY DQAPDAMRSL CSALSLTAIA
510 520 530 540 550
FGNYLSTFLV TLVTKVTRSG GRPGWIAKNL NNGHLDYFFW LLAGLSFLNF
560 570
LVYLWIAKWY TYKKTTGHAL
Length:570
Mass (Da):63,308
Last modified:October 1, 2000 - v1
Checksum:i4603B9B64BB20CF5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti302T → A in AAO64143 (PubMed:14593172).Curated1
Sequence conflicti302T → A in BAF00365 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137189 Genomic DNA Translation: CAB69846.1
CP002688 Genomic DNA Translation: AED90307.1
CP002688 Genomic DNA Translation: ANM69606.1
CP002688 Genomic DNA Translation: ANM69607.1
BT005728 mRNA Translation: AAO64143.1
AK228435 mRNA Translation: BAF00365.1
PIRiT45958
RefSeqiNP_001331271.1, NM_001342576.1
NP_001331272.1, NM_001342577.1
NP_195738.1, NM_120196.4
UniGeneiAt.33937

Genome annotation databases

EnsemblPlantsiAT5G01180.1; AT5G01180.1; AT5G01180
AT5G01180.2; AT5G01180.2; AT5G01180
AT5G01180.3; AT5G01180.3; AT5G01180
GeneIDi831725
GrameneiAT5G01180.1; AT5G01180.1; AT5G01180
AT5G01180.2; AT5G01180.2; AT5G01180
AT5G01180.3; AT5G01180.3; AT5G01180
KEGGiath:AT5G01180

Similar proteinsi

Entry informationi

Entry nameiPTR5_ARATH
AccessioniPrimary (citable) accession number: Q9LFB8
Secondary accession number(s): Q0WR84, Q84TJ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health