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Protein

Beta-galactosidase 2

Gene

BGAL2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei185Proton donorSequence analysis1
Active sitei254NucleophileSequence analysis1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Enzyme and pathway databases

BRENDAi3.2.1.23 399

Protein family/group databases

CAZyiGH35 Glycoside Hydrolase Family 35

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase 2 (EC:3.2.1.23)
Short name:
Lactase 2
Gene namesi
Name:BGAL2
Ordered Locus Names:At3g52840
ORF Names:F8J2.10
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G52840
TAIRilocus:2085131 AT3G52840

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500006587828 – 727Beta-galactosidase 2Add BLAST700

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi255N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9LFA6
PRIDEiQ9LFA6

Expressioni

Tissue specificityi

Ubiquitous, with higher expression levels in roots and siliques.2 Publications

Inductioni

By sugar starvation.1 Publication

Gene expression databases

ExpressionAtlasiQ9LFA6 baseline and differential
GenevisibleiQ9LFA6 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G52840.1

Structurei

3D structure databases

ProteinModelPortaliQ9LFA6
SMRiQ9LFA6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 35 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG0496 Eukaryota
COG1874 LUCA
HOGENOMiHOG000239919
InParanoidiQ9LFA6
KOiK12309
OMAiIYNEKKC
OrthoDBiEOG093601RS

Family and domain databases

Gene3Di2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR031330 Gly_Hdrlase_35_cat
IPR019801 Glyco_hydro_35_CS
IPR001944 Glycoside_Hdrlase_35
IPR017853 Glycoside_hydrolase_SF
PANTHERiPTHR23421 PTHR23421, 1 hit
PfamiView protein in Pfam
PF01301 Glyco_hydro_35, 1 hit
PRINTSiPR00742 GLHYDRLASE35
SUPFAMiSSF49785 SSF49785, 3 hits
SSF51445 SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS01182 GLYCOSYL_HYDROL_F35, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9LFA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMHFRNKAW IILAILCFSS LIHSTEAVVT YDHKALIING QRRILISGSI
60 70 80 90 100
HYPRSTPEMW PDLIKKAKEG GLDVIQTYVF WNGHEPSPGN YYFQDRYDLV
110 120 130 140 150
KFTKLVHQAG LYLDLRIGPY VCAEWNFGGF PVWLKYVPGM VFRTDNEPFK
160 170 180 190 200
IAMQKFTKKI VDMMKEEKLF ETQGGPIILS QIENEYGPMQ WEMGAAGKAY
210 220 230 240 250
SKWTAEMALG LSTGVPWIMC KQEDAPYPII DTCNGFYCEG FKPNSDNKPK
260 270 280 290 300
LWTENWTGWF TEFGGAIPNR PVEDIAFSVA RFIQNGGSFM NYYMYYGGTN
310 320 330 340 350
FDRTAGVFIA TSYDYDAPID EYGLLREPKY SHLKELHKVI KLCEPALVSV
360 370 380 390 400
DPTITSLGDK QEIHVFKSKT SCAAFLSNYD TSSAARVMFR GFPYDLPPWS
410 420 430 440 450
VSILPDCKTE YYNTAKIRAP TILMKMIPTS TKFSWESYNE GSPSSNEAGT
460 470 480 490 500
FVKDGLVEQI SMTRDKTDYF WYFTDITIGS DESFLKTGDN PLLTIFSAGH
510 520 530 540 550
ALHVFVNGLL AGTSYGALSN SKLTFSQNIK LSVGINKLAL LSTAVGLPNA
560 570 580 590 600
GVHYETWNTG ILGPVTLKGV NSGTWDMSKW KWSYKIGLRG EAMSLHTLAG
610 620 630 640 650
SSAVKWWIKG FVVKKQPLTW YKSSFDTPRG NEPLALDMNT MGKGQVWVNG
660 670 680 690 700
HNIGRHWPAY TARGNCGRCN YAGIYNEKKC LSHCGEPSQR WYHVPRSWLK
710 720
PFGNLLVIFE EWGGDPSGIS LVKRTAK
Length:727
Mass (Da):82,015
Last modified:May 3, 2011 - v2
Checksum:i21FF54744E67F5C5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti12I → F in AAN60229 (Ref. 5) Curated1
Sequence conflicti220C → S in CAB86888 (PubMed:11130713).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ270298 mRNA Translation: CAB64738.1
AL132969 Genomic DNA Translation: CAB86888.1
CP002686 Genomic DNA Translation: AEE78999.1
AF367327 mRNA Translation: AAK32914.1
BT000511 mRNA Translation: AAN18080.1
AF083670 mRNA Translation: AAN60229.1
PIRiT47541
RefSeqiNP_190852.2, NM_115144.4
UniGeneiAt.702

Genome annotation databases

EnsemblPlantsiAT3G52840.1; AT3G52840.1; AT3G52840
AT3G52840.2; AT3G52840.2; AT3G52840
GeneIDi824450
GrameneiAT3G52840.1; AT3G52840.1; AT3G52840
AT3G52840.2; AT3G52840.2; AT3G52840
KEGGiath:AT3G52840

Similar proteinsi

Entry informationi

Entry nameiBGAL2_ARATH
AccessioniPrimary (citable) accession number: Q9LFA6
Secondary accession number(s): Q8H7H7, Q9SCW0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 3, 2011
Last modified: April 25, 2018
This is version 114 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health