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Protein

Protein HUA2-LIKE 1

Gene

HULK1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Probable transcrition factor that acts with partial redundancy with HULK2 and HULK3. Plays diverse and essential roles in the control of plant development, physiology and flowering time.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Flowering, mRNA processing, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HUA2-LIKE 11 Publication
Alternative name(s):
HUA2-like protein 1Curated
Gene namesi
Name:HULK11 Publication
Ordered Locus Names:At5g08230Imported
ORF Names:T22D6_170
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G08230.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: TAIR
  • plasmodesma Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

No visible phenotype under normal growth conditions, but the triple mutant plants hulk1, hulk2 and hulk3 show delayed flowering.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14451445Protein HUA2-LIKE 1PRO_0000418857Add
BLAST

Proteomic databases

PaxDbiQ9LEY4.
PRIDEiQ9LEY4.

PTM databases

iPTMnetiQ9LEY4.

Expressioni

Tissue specificityi

Expressed throughout young primordia, and vegetative and reproductive apices.1 Publication

Gene expression databases

GenevisibleiQ9LEY4. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G08230.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LEY4.
SMRiQ9LEY4. Positions 21-74.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 7758PWWPPROSITE-ProRule annotationAdd
BLAST
Domaini838 – 979142CIDPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi433 – 4386Poly-Ser
Compositional biasi458 – 4658Poly-Asp
Compositional biasi725 – 7306Poly-Ser
Compositional biasi1119 – 120789Pro-richAdd
BLAST

Sequence similaritiesi

Contains 1 CID domain.PROSITE-ProRule annotation
Contains 1 PWWP domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1904. Eukaryota.
ENOG410Y5WD. LUCA.
HOGENOMiHOG000090612.
InParanoidiQ9LEY4.
OMAiENEERRF.
PhylomeDBiQ9LEY4.

Family and domain databases

InterProiIPR006569. CID_dom.
IPR000313. PWWP_dom.
IPR006903. RNA_pol_II-bd.
[Graphical view]
PfamiPF04818. CTD_bind. 1 hit.
PF00855. PWWP. 1 hit.
[Graphical view]
SMARTiSM00293. PWWP. 1 hit.
SM00582. RPR. 1 hit.
[Graphical view]
PROSITEiPS51391. CID. 1 hit.
PS50812. PWWP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LEY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPGRKRGAN KAMAIGEMRL GDLVLAKVKG FPAWPAKIGQ PEDWNQAPDP
60 70 80 90 100
KKHFVQFYGT GEIGFVTPPD IQPFTSETKK KLSARCQGKT VKYFSQAVEE
110 120 130 140 150
ISAAFEESQK QKSDIVGNEA LLNAVEPSVT KPKYLNQASS DGKSDKFSSR
160 170 180 190 200
ADPCLGKLVE NNGAEINPDV GEQDSSISNN RNTSPSSEPV EHGSPDPILK
210 220 230 240 250
VAVDDKIDNV TCTDHSDGTG NNLVNDQRII RKTTDDSNKR CKDEVRAKRV
260 270 280 290 300
PDSRAATDNH ILGPNQKLKG SIKGQDHGSK KGQDHGCRKE SSDSKVVTDL
310 320 330 340 350
NIASSKKPKE LLKEKKKRFE NELGKSASGA DESKRAAKRP RSEDAKDQKQ
360 370 380 390 400
CKSKRLVPVG EGKAEISDST GVVSIFKREI VLGISALGGK NQFDKDMVAY
410 420 430 440 450
TKRRKQTVEH TSVSSFPGSL VKEGANHPEQ KISSSSDSDI KVQAAQLPKR
460 470 480 490 500
RRAVCIYDDD DDDEDPKTPV HGGLSNIPIA STDAPKSANA SHNTSIKAKL
510 520 530 540 550
LAGSTDSVKT GKVPLYKHNK DASLALPDSV EGYNSRMGKP FKALLQKNIK
560 570 580 590 600
PILRSPKNSY QLVSFKKQVT GQNKTAKVAG AGMPDSVEGP SNSSYMGKPV
610 620 630 640 650
IKLPPQNVKQ TLRSPKKSPQ LFSTKELVAV QNKIAKVSGA GIPKKYHGDS
660 670 680 690 700
SKDVVAGSDR VSSSHSQTAN QRSKPAFGEK PTSTPKVATR LDVEVSRDTF
710 720 730 740 750
VNLSADVIDV NQENGNAPLF SFGMSDSSSS CMKDLIAAAQ AKRKQAHSQF
760 770 780 790 800
SPFVNLDHNS LNIDSMQTSK SPFMVQNVSS PAADATLIVA QEHQEVLTPS
810 820 830 840 850
NHGRQSSSSN QAGTEENEER RFSSGHRSVG GSLSGATEAA ISRDTFEGMI
860 870 880 890 900
ETLSRTKESI RRATRVAIDC AKYGIANEVV ELLIRKLEIE PHFPRKVDLF
910 920 930 940 950
FLLDSIIQSS HSQKGRARSL YIPTVQAALP RLLGAAAPPG TGARENRHQC
960 970 980 990 1000
RKVLRLWLKR KIFPDFLLRR YIGDLGASGD DKTVGFSLRR PSRSERAVDD
1010 1020 1030 1040 1050
PLRDMEGMLV DEYGSNANFQ LPGYLASLTF GDDEEEDLPS TSQEVKNTHM
1060 1070 1080 1090 1100
EVKITHMEEP VLALGKLEAH DSSSDKPHCV VDVNGGLEME DASCQLKDDV
1110 1120 1130 1140 1150
CGIEAKEDSP ATTCATELPS FPAGSPPLPH ESPPSPPPQP PSSPPPPSSP
1160 1170 1180 1190 1200
PQLAPAPPPS DHCLPPPTAP LAPAQSIALP PSSITRPSMP SHPSLPLQPG
1210 1220 1230 1240 1250
FAPPAYPLLQ HEYQISMQRD HSSIATSNQI APVPVNAAHG RHADGGVKSE
1260 1270 1280 1290 1300
YLMPQSSSFA PVGMCSYGEP LPFISSKQLE YGNSDVLFKQ EASSQNQQLR
1310 1320 1330 1340 1350
PINTSFLQRP MIRNLAPAPS SHFPLPCRIV QSEPQRSSFP HPYHFPSQPV
1360 1370 1380 1390 1400
DGRQHMNEEW RMPPNGCSAD PQYGAWIGVR NPFPGSRTVT DGVFQPPPER
1410 1420 1430 1440
PPSGTVRYQL AANNLQGGST ISGNIASQML LSRPDVPSAA QYRPS
Length:1,445
Mass (Da):156,555
Last modified:October 1, 2000 - v1
Checksum:i3969FAF2868AD8FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL357612 Genomic DNA. Translation: CAB93724.1.
CP002688 Genomic DNA. Translation: AED91271.1.
AK229633 mRNA. Translation: BAF01478.1.
PIRiT50508.
RefSeqiNP_196440.1. NM_120906.5.
UniGeneiAt.22840.

Genome annotation databases

EnsemblPlantsiAT5G08230.1; AT5G08230.1; AT5G08230.
GeneIDi830719.
GrameneiAT5G08230.1; AT5G08230.1; AT5G08230.
KEGGiath:AT5G08230.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL357612 Genomic DNA. Translation: CAB93724.1.
CP002688 Genomic DNA. Translation: AED91271.1.
AK229633 mRNA. Translation: BAF01478.1.
PIRiT50508.
RefSeqiNP_196440.1. NM_120906.5.
UniGeneiAt.22840.

3D structure databases

ProteinModelPortaliQ9LEY4.
SMRiQ9LEY4. Positions 21-74.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G08230.1.

PTM databases

iPTMnetiQ9LEY4.

Proteomic databases

PaxDbiQ9LEY4.
PRIDEiQ9LEY4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G08230.1; AT5G08230.1; AT5G08230.
GeneIDi830719.
GrameneiAT5G08230.1; AT5G08230.1; AT5G08230.
KEGGiath:AT5G08230.

Organism-specific databases

TAIRiAT5G08230.

Phylogenomic databases

eggNOGiKOG1904. Eukaryota.
ENOG410Y5WD. LUCA.
HOGENOMiHOG000090612.
InParanoidiQ9LEY4.
OMAiENEERRF.
PhylomeDBiQ9LEY4.

Miscellaneous databases

PROiQ9LEY4.

Gene expression databases

GenevisibleiQ9LEY4. AT.

Family and domain databases

InterProiIPR006569. CID_dom.
IPR000313. PWWP_dom.
IPR006903. RNA_pol_II-bd.
[Graphical view]
PfamiPF04818. CTD_bind. 1 hit.
PF00855. PWWP. 1 hit.
[Graphical view]
SMARTiSM00293. PWWP. 1 hit.
SM00582. RPR. 1 hit.
[Graphical view]
PROSITEiPS51391. CID. 1 hit.
PS50812. PWWP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
    Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
    , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
    Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1317-1445.
    Strain: cv. Columbia.
  4. "A plant-specific HUA2-LIKE (HULK) gene family in Arabidopsis thaliana is essential for development."
    Jali S.S., Rosloski S.M., Janakirama P., Steffen J.G., Zhurov V., Berleth T., Clark R.M., Grbic V.
    Plant J. 80:242-254(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.

Entry informationi

Entry nameiHUAL1_ARATH
AccessioniPrimary (citable) accession number: Q9LEY4
Secondary accession number(s): Q0WN22
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2012
Last sequence update: October 1, 2000
Last modified: May 11, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.