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Q9LEC8 (DHEB_NICPL) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate dehydrogenase B

Short name=GDH B
EC=1.4.1.3
Gene names
Name:GDHB
OrganismNicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco)
Taxonomic identifier4092 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length411 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.

Sequence similarities

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processcellular amino acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutamate dehydrogenase [NAD(P)+] activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 411411Glutamate dehydrogenase B
PRO_0000182751

Sites

Active site1021 By similarity

Experimental info

Sequence conflict921A → R in CAA69601. Ref.1
Sequence conflict3681A → D in CAA69601. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9LEC8 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 236D4915B8B670AE

FASTA41144,508
        10         20         30         40         50         60 
MNALAATNRN FKLASRLLGL DSKLEQCLLI PFREIKVECT IPKDDGSLAT FIGFRVQHDN 

        70         80         90        100        110        120 
ARGPMKGGIR YHPEVDPDEV NALAQLMTWK TAVANIPYGG AKGGIGCSPS DLSISELERL 

       130        140        150        160        170        180 
TRVFTQKIHD LIGVHTDVPA PDMGTNPQTM AWILDEYSKF HGYSPAVVTG KPIDLGGSLG 

       190        200        210        220        230        240 
RDAATGRGVL FAAEALLRDH GKSIAGQRFV VQGFGNVGSW AAQLITEQGG KIVAVSDITG 

       250        260        270        280        290        300 
AIKNKNGIDI ASLLKHVKEN RGVKGFHGAD SIDPNSILVE DCDVLIPAAL GGVINRDNAK 

       310        320        330        340        350        360 
DIKAKFIVEA ANHPTDPEAD EILAKKGVVI LPDIYANSGG VTVSYFEWVQ NIQGFMWDEE 

       370        380        390        400        410 
RVNTELKAYM NRGFKDVKDM CKTHNCDLRM GAFTLGVNRV ARATTLRGWE A 

« Hide

References

[1]"Isolation and characterization of two cDNA clones encoding for glutamate dehydrogenase in Nicotiana plumbaginifolia."
Ficarelli A., Tassi F., Restivo F.M.
Plant Cell Physiol. 40:339-342(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Leaf.
[2]"Genomic organisation of GDH genes in Nicotiana plumbaginifolia."
Restivo F.M., Panizzi N., De Monte G., Ficarelli A.
Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y08293 Genomic DNA. Translation: CAA69601.2.
AJ277950 Genomic DNA. Translation: CAB94837.1.
PIRT16982.

3D structure databases

ProteinModelPortalQ9LEC8.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

ProMEXQ9LEC8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFPIRSF000185. Glu_DH. 1 hit.
PRINTSPR00082. GLFDHDRGNASE.
SMARTSM00839. ELFV_dehydrog. 1 hit.
[Graphical view]
PROSITEPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDHEB_NICPL
AccessionPrimary (citable) accession number: Q9LEC8
Secondary accession number(s): O24119
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: October 1, 2000
Last modified: July 9, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families