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Protein

Ethylene-responsive transcription factor 7

Gene

ERF7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the regulation of gene expression by abscisic acid, stress factors and by components of stress signal transduction pathways. Transcription factor that binds to the GCC-box pathogenesis-related promoter element. Part of a transcriptional repressor complex including a histone deacetylase.2 Publications

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi26 – 8358AP2/ERFPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • sequence-specific DNA binding Source: TAIR
  • transcription factor activity, sequence-specific DNA binding Source: TAIR
  • transcription regulatory region DNA binding Source: TAIR

GO - Biological processi

  • defense response Source: UniProtKB-KW
  • ethylene-activated signaling pathway Source: TAIR
  • negative regulation of transcription, DNA-templated Source: TAIR
  • regulation of transcription, DNA-templated Source: TAIR
  • response to abscisic acid Source: TAIR
  • response to water deprivation Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Ethylene signaling pathway, Plant defense, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ethylene-responsive transcription factor 7
Short name:
AtERF7
Alternative name(s):
Ethylene-responsive element-binding factor 7
Short name:
EREBP-7
Gene namesi
Name:ERF7
Synonyms:ERF-7, ERF083
Ordered Locus Names:At3g20310
ORF Names:MQC12.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G20310.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation1 Publication

GO - Cellular componenti

  • nucleus Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 244244Ethylene-responsive transcription factor 7PRO_0000112557Add
BLAST

Post-translational modificationi

Phosphorylated by PKS3.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9LDE4.
PRIDEiQ9LDE4.

PTM databases

iPTMnetiQ9LDE4.

Expressioni

Gene expression databases

GenevisibleiQ9LDE4. AT.

Interactioni

Subunit structurei

Interacts with SIN3 and HDA19.1 Publication

Protein-protein interaction databases

BioGridi6907. 7 interactions.
IntActiQ9LDE4. 1 interaction.
STRINGi3702.AT3G20310.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LDE4.
SMRiQ9LDE4. Positions 27-84.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi217 – 2237EAR-like (transcriptional repression)

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi193 – 1964Poly-Ser
Compositional biasi206 – 2094Poly-Ser

Domaini

Contains a slightly degenerated ERF-associated amphiphilic repression (EAR) motif, which may be involved in the activity of transcriptional repression.By similarity

Sequence similaritiesi

Contains 1 AP2/ERF DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IZCZ. Eukaryota.
ENOG410YQNQ. LUCA.
HOGENOMiHOG000237624.
KOiK09286.
OMAiHAIKRYP.
PhylomeDBiQ9LDE4.

Family and domain databases

Gene3Di3.30.730.10. 1 hit.
InterProiIPR001471. AP2/ERF_dom.
IPR016177. DNA-bd_dom.
[Graphical view]
PfamiPF00847. AP2. 1 hit.
[Graphical view]
PRINTSiPR00367. ETHRSPELEMNT.
SMARTiSM00380. AP2. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS51032. AP2_ERF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9LDE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKGRGSSVV GPALPVTAGG SVKEPRYRGV RKRPWGRFAA EIRDPLKKSR
60 70 80 90 100
VWLGTFDSAV DAARAYDTAA RNLRGPKAKT NFPIDCSPSS PLQPLTYLHN
110 120 130 140 150
QNLCSPPVIQ NQIDPFMDHR LYGGGNFQEQ QQQQIISRPA SSSMSSTVKS
160 170 180 190 200
CSGPRPMEAA AASSSVAKPL HAIKRYPRTP PVAPEDCHSD CDSSSSVIDD
210 220 230 240
GDDIASSSSR RKTPFQFDLN FPPLDGVDLF AGGIDDLHCT DLRL
Length:244
Mass (Da):26,509
Last modified:October 1, 2000 - v1
Checksum:iB87391FDE706E21C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB032201 mRNA. Translation: BAA96653.1.
AB024036 Genomic DNA. Translation: BAB02811.1.
CP002686 Genomic DNA. Translation: AEE76362.1.
AY037254 mRNA. Translation: AAK59855.1.
AY094001 mRNA. Translation: AAM16262.1.
AY085023 mRNA. Translation: AAM61581.1.
AK228460 mRNA. Translation: BAF00387.1.
RefSeqiNP_188666.1. NM_112922.2.
UniGeneiAt.20161.

Genome annotation databases

EnsemblPlantsiAT3G20310.1; AT3G20310.1; AT3G20310.
GeneIDi821575.
GrameneiAT3G20310.1; AT3G20310.1; AT3G20310.
KEGGiath:AT3G20310.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB032201 mRNA. Translation: BAA96653.1.
AB024036 Genomic DNA. Translation: BAB02811.1.
CP002686 Genomic DNA. Translation: AEE76362.1.
AY037254 mRNA. Translation: AAK59855.1.
AY094001 mRNA. Translation: AAM16262.1.
AY085023 mRNA. Translation: AAM61581.1.
AK228460 mRNA. Translation: BAF00387.1.
RefSeqiNP_188666.1. NM_112922.2.
UniGeneiAt.20161.

3D structure databases

ProteinModelPortaliQ9LDE4.
SMRiQ9LDE4. Positions 27-84.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi6907. 7 interactions.
IntActiQ9LDE4. 1 interaction.
STRINGi3702.AT3G20310.1.

PTM databases

iPTMnetiQ9LDE4.

Proteomic databases

PaxDbiQ9LDE4.
PRIDEiQ9LDE4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G20310.1; AT3G20310.1; AT3G20310.
GeneIDi821575.
GrameneiAT3G20310.1; AT3G20310.1; AT3G20310.
KEGGiath:AT3G20310.

Organism-specific databases

TAIRiAT3G20310.

Phylogenomic databases

eggNOGiENOG410IZCZ. Eukaryota.
ENOG410YQNQ. LUCA.
HOGENOMiHOG000237624.
KOiK09286.
OMAiHAIKRYP.
PhylomeDBiQ9LDE4.

Miscellaneous databases

PROiQ9LDE4.

Gene expression databases

GenevisibleiQ9LDE4. AT.

Family and domain databases

Gene3Di3.30.730.10. 1 hit.
InterProiIPR001471. AP2/ERF_dom.
IPR016177. DNA-bd_dom.
[Graphical view]
PfamiPF00847. AP2. 1 hit.
[Graphical view]
PRINTSiPR00367. ETHRSPELEMNT.
SMARTiSM00380. AP2. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS51032. AP2_ERF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Arabidopsis ERF family."
    Fujimoto S.Y., Ohta M., Usui A., Shinshi H., Ohme-Takagi M.
    Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones."
    Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.
    DNA Res. 7:131-135(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  6. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  7. "Repression domains of class II ERF transcriptional repressors share an essential motif for active repression."
    Ohta M., Matsui K., Hiratsu K., Shinshi H., Ohme-Takagi M.
    Plant Cell 13:1959-1968(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  8. "Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses."
    Song C.-P., Agarwal M., Ohta M., Guo Y., Halfter U., Wang P., Zhu J.-K.
    Plant Cell 17:2384-2396(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, PHOSPHORYLATION, SUBCELLULAR LOCATION, INTERACTION WITH SIN3 AND HDA19.
  9. "Genome-wide analysis of the ERF gene family in Arabidopsis and rice."
    Nakano T., Suzuki K., Fujimura T., Shinshi H.
    Plant Physiol. 140:411-432(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiERF83_ARATH
AccessioniPrimary (citable) accession number: Q9LDE4
Secondary accession number(s): Q0WR62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: October 1, 2000
Last modified: June 8, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.